Most cited biochemistry, genetics and molecular biology papers
- Verified
Chimeric nucleases stimulate gene targeting in human cells
Porteus, M. H., & Baltimore, D. (2003) · Science
CRISPR and Genetic EngineeringDNA Repair Mechanisms
Cited by 741
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Estrogen, cytokines, and pathogenesis of postmenopausal osteoporosis
Pacifici, R. (1996) · Journal of Bone and Mineral Research
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 741
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A positive-feedback-based bistable ‘memory module’ that governs a cell fate decision.
Xiong, W., & Ferrell, J. E. (2003) · Nature
Gene Regulatory Network AnalysisDevelopmental Biology and Gene Regulation
Cited by 741
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Impact of Omega-3 Fatty Acids on the Gut Microbiota
Costantini, L., Molinari, R., Farinon, B., & Merendino, N. (2017) · International Journal of Molecular Sciences
Gut microbiota and healthFatty Acid Research and Health
Cited by 741
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Catastrophic nuclear envelope collapse in cancer cell micronuclei
Hatch, E. M., Fischer, A. H., Deerinck, T. J., & Hetzer, M. W. (2013) · Cell
Nuclear Structure and FunctionMicrotubule and mitosis dynamics
Cited by 741
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Recombinant AAV Viral Vectors Pseudotyped with Viral Capsids from Serotypes 1, 2, and 5 Display Differential Efficiency and Cell Tropism after Delivery to Different Regions of the Central Nervous System
Burger, C., Gorbatyuk, O. S., Velardo, M. J., Peden, C. S., Williams, P., Zolotukhin, S., Reier, P. J., Mandel, R. J., & Muzyczka, N. (2004) · Molecular Therapy
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 741
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Small-molecule–induced DNA damage identifies alternative DNA structures in human genes
Rodriguez, R., Miller, K. M., Forment, J. V., Bradshaw, C. R., Nikan, M., Britton, S., Oelschlaegel, T., Xhemalce, B., Balasubramanian, S., & Jackson, S. P. (2012) · Nature Chemical Biology
DNA and Nucleic Acid ChemistryMetal complexes synthesis and properties
Cited by 741
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Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis
Vujkovic, M., Keaton, J. M., Lynch, J. A., Miller, D. R., Zhou, J., Tcheandjieu, C., Huffman, J. E., Assimes, T. L., Lorenz, K., Zhu, X., et al. (2020) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 741
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The intestinal microbiota: Antibiotics, colonization resistance, and enteric pathogens
Kim, S., Covington, A., & Pamer, E. G. (2017) · Immunological Reviews
Gut microbiota and healthClostridium difficile and Clostridium perfringens research
Cited by 741
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The limits of selection during maize domestication
Wang, R.-L., Stec, A., Hey, J., Lukens, L., & Doebley, J. (1999) · Nature
Genetic Mapping and Diversity in Plants and AnimalsGenetic diversity and population structure
Cited by 740
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p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis
Vaseva, A. V., Marchenko, N. D., Ji, K., Tsirka, S. E., Holzmann, S., & Moll, U. M. (2012) · Cell
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 740
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Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: Comparison with 2′,7′-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2′,7′-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123
Hempel, S. L., Buettner, G. R., O’Malley, Y. Q., Wessels, D. A., & Flaherty, D. M. (1999) · Free Radical Biology and Medicine
Redox biology and oxidative stressMolecular Sensors and Ion Detection
Cited by 740
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HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo
Zhang, Y., Li, N., Caron, C., Matthias, G., Hess, D., Khochbin, S., & Matthias, P. (2003) · The EMBO Journal
Histone Deacetylase Inhibitors ResearchMicrotubule and mitosis dynamics
Cited by 740
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MicroRNA-Mediated Feedback and Feedforward Loops Are Recurrent Network Motifs in Mammals
Tsang, J., Zhu, J., & van Oudenaarden, A. (2007) · Molecular Cell
MicroRNA in disease regulationGene Regulatory Network Analysis
Cited by 740
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Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors
Lemos, D. R., Babaeijandaghi, F., Low, M., Chang, C.-K., Lee, S. T., Fiore, D., Zhang, R.-H., Natarajan, A., Nedospasov, S. A., & Rossi, F. M. V. (2015) · Nature Medicine
Muscle Physiology and DisordersCardiac Fibrosis and Remodeling
Cited by 740
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Control of Cell Morphogenesis in Bacteria
Daniel, R. A., & Errington, J. (2003) · Cell
Bacterial Genetics and BiotechnologyBiochemical and Structural Characterization
Cited by 740
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Regulation of Muscle Growth and Regeneration by the Immune System
Tidball, J. G. (2017) · Nature Reviews Immunology
Muscle Physiology and DisordersWound Healing and Treatments
Cited by 740
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Drugs from the deep: Marine natural products as drug candidates
Haefner, B. (2003) · Drug Discovery Today
Marine Sponges and Natural ProductsMicrobial Natural Products and Biosynthesis
Cited by 740
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Biochemical and cellular properties of insulin receptor signalling
Haeusler, R. A., McGraw, T. E., & Accili, D. (2018) · Nature Reviews Molecular Cell Biology
Metabolism, Diabetes, and CancerPancreatic function and diabetes
Cited by 739
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Correlation Between Deoxyribonucleic Acid Excision-Repair and Life-Span in a Number of Mammalian Species
Hart, R. W., & Setlow, R. B. (1974) · Proceedings of the National Academy of Sciences
DNA Repair MechanismsGenetics, Aging, and Longevity in Model Organisms
Cited by 739
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Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain
Mo, A., Mukamel, E. A., Davis, F. P., Luo, C., Henry, G. L., Picard, S., Urich, M. A., Nery, J. R., Sejnowski, T. J., Lister, R., et al. (2015) · Neuron
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 739
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Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1
Ben-Sahra, I., Howell, J. J., Asara, J. M., & Manning, B. D. (2013) · Science
Biochemical and Molecular ResearchPI3K/AKT/mTOR signaling in cancer
Cited by 739
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The emerging role of ferroptosis in inflammation
Sun, Y., Chen, P., Zhai, B., Zhang, M., Xiang, Y., Fang, J., Xu, S., Gao, Y., Chen, X., Sui, X., et al. (2020) · Biomedicine & Pharmacotherapy
Ferroptosis and cancer prognosisIron Metabolism and Disorders
Cited by 739
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Data-analysis strategies for image-based cell profiling
Caicedo, J. C., Cooper, S., Heigwer, F., Warchal, S., Qiu, P., Molnar, C., Vasilevich, A. S., Barry, J. D., Bansal, H. S., Kraus, O., et al. (2017) · Nature Methods
Cell Image Analysis TechniquesSingle-cell and spatial transcriptomics
Cited by 739
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