Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species

Shen, H.-M., & Liu, Z.-G. (2006) · Free Radical Biology and Medicine

Redox biology and oxidative stressCell death mechanisms and regulation

Cited by 629

Transactivation and Inhibitory Domains of Hypoxia-inducible Factor 1α

Jiang, B.-H., Zheng, J. Z., Leung, S. W., Roe, R., & Semenza, G. L. (1997) · Journal of Biological Chemistry

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 629

De novo protein design by deep network hallucination

Anishchenko, I., Chidyausiku, T. M., Ovchinnikov, S., Pellock, S. J., & Baker, D. (2020) · Nature

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 629

Phyutility: A phyloinformatics tool for trees, alignments and molecular data

Smith, S. A., & Dunn, C. W. (2008) · Bioinformatics

Genomics and Phylogenetic StudiesGenetics, Bioinformatics, and Biomedical Research

Cited by 629

Defining the role of the tumor vasculature in antitumor immunity and immunotherapy

Schaaf, M. B., Garg, A. D., & Agostinis, P. (2018) · Cell Death & Disease

Angiogenesis and VEGF in CancerCancer Immunotherapy and Biomarkers

Cited by 629

Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

Lovejoy, C. A., Li, W., Reisenweber, S., Thongthip, S., Bruno, J., de Lange, T., De, S., Petrini, J. H. J., Sung, P. A., Jasin, M., et al. (2012) · PLoS Genetics

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 629

An ionizable lipid toolbox for RNA delivery

Han, X., Zhang, H., Butowska, K., Swingle, K. L., Alameh, M.-G., Weissman, D., & Mitchell, M. J. (2021) · Nature Communications

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 628

Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11.

Karayiorgou, M., Morris, M. A., Morrow, B., Shprintzen, R. J., Goldberg, R., Borrow, J., Gos, A., Nestadt, G., Wolyniec, P. S., & Lasseter, V. K. (1995) · Proceedings of the National Academy of Sciences

Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment

Cited by 628

Target RNA–Directed Trimming and Tailing of Small Silencing RNAs

Ameres, S. L., Horwich, M. D., Hung, J.-H., Xu, J., Ghildiyal, M., Weng, Z., & Zamore, P. D. (2010) · Science

RNA Interference and Gene DeliveryMicroRNA in disease regulation

Cited by 628

β-Catenin destruction complex: insights and questions from a structural perspective

Kimelman, D., & Xu, W. (2006) · Oncogene

Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease

Cited by 628

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

Schwickart, M., Huang, X., Lill, J. R., Liu, J., Ferrando, R., French, D. M., Maecker, H., O’Rourke, K., Bazan, F., Eastham-Anderson, J., et al. (2010) · Nature

Ubiquitin and proteasome pathwaysCell death mechanisms and regulation

Cited by 628

Age-related remodelling of oesophageal epithelia by mutated cancer drivers

Yokoyama, A., Kakiuchi, N., Yoshizato, T., Nannya, Y., Suzuki, H., Takeuchi, Y., Shiozawa, Y., Sato, Y., Aoki, K., Kim, S. K., et al. (2019) · Nature

Cancer Genomics and DiagnosticsEsophageal Cancer Research and Treatment

Cited by 628

A comparison of automatic cell identification methods for single-cell RNA sequencing data

Abdelaal, T., Michielsen, L., Cats, D., Hoogduin, D., Mei, H., Reinders, M. J. T., & Mahfouz, A. (2019) · Genome Biology

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 628

Notochord repression of endodermal Sonic hedgehog permits pancreas development

Hebrok, M., Kim, S. K., & Melton, D. A. (1998) · Genes & Development

Hedgehog Signaling Pathway StudiesDevelopmental Biology and Gene Regulation

Cited by 628

Adiposity, gut microbiota and faecal short chain fatty acids are linked in adult humans

Fernandes, J., Su, W., Rahat-Rozenbloom, S., Wolever, T. M. S., & Comelli, E. M. (2014) · Nutrition & Diabetes

Gut microbiota and healthNutritional Studies and Diet

Cited by 628

Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors

Ahola-Olli, A. V., Würtz, P., Havulinna, A. S., Aalto, K., Pitkänen, N., Lehtimäki, T., Kähönen, M., Lyytikäinen, L.-P., Raitoharju, E., Seppälä, I., et al. (2017) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 628

CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer

Griffith, M., Spies, N. C., Krysiak, K., McMichael, J. F., Coffman, A. C., Danos, A. M., Ainscough, B. J., Ramirez, C. A., Rieke, D. T., Kujan, L., et al. (2017) · Nature Genetics

Genomics and Rare DiseasesCancer Genomics and Diagnostics

Cited by 628

TGFβ1 Inhibits the Formation of Benign Skin Tumors, but Enhances Progression to Invasive Spindle Carcinomas in Transgenic Mice

Cui, W., Fowlis, D. J., Bryson, S., Duffie, E., Ireland, H., Balmain, A., & Akhurst, R. J. (1996) · Cell

TGF-β signaling in diseasesCancer Cells and Metastasis

Cited by 628

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase‐1 and p70 S6 kinase

Alessi, D. R., Barry Caudwell, F., Andjelkovic, M., Hemmings, B. A., & Cohen, P. (1996) · FEBS Letters

Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer

Cited by 628

Assessing the evolutionary impact of amino acid mutations in the human genome.

Boyko, A. R., Williamson, S. H., Indap, A. R., Degenhardt, J. D., Hernandez, R. D., Lohmueller, K. E., Adams, M. D., Schmidt, S., Sninsky, J. J., Sunyaev, S. R., et al. (2008) · PLoS Genetics

Evolution and Genetic DynamicsForensic and Genetic Research

Cited by 628

The Salvador–Warts–Hippo pathway — an emerging tumour-suppressor network

Harvey, K., & Tapon, N. (2007) · Nature Reviews Cancer

Hippo pathway signaling and YAP/TAZPI3K/AKT/mTOR signaling in cancer

Cited by 628

Akt Forms an Intracellular Complex with Heat Shock Protein 90 (Hsp90) and Cdc37 and Is Destabilized by Inhibitors of Hsp90 Function

Basso, A. D., Solit, D. B., Chiosis, G., Giri, B., Tsichlis, P., & Rosen, N. (2002) · Journal of Biological Chemistry

Heat shock proteins researchPI3K/AKT/mTOR signaling in cancer

Cited by 628

Structure and mechanogating mechanism of the Piezo1 channel

Zhao, Q., Zhou, H., Chi, S., Wang, Y., Wang, J., Geng, J., Wu, K., Liu, W., Zhang, T., Dong, M.-Q., et al. (2018) · Nature

Ion channel regulation and functionIon Channels and Receptors

Cited by 628

Large-scale foundation model on single-cell transcriptomics

Hao, M., Gong, J., Zeng, X., Liu, C., Guo, Y., Cheng, X., Wang, T., Ma, J., Zhang, X., & Song, L. (2024) · Nature Methods

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 628