Most cited biochemistry, genetics and molecular biology papers
- Verified
FGF19 as a Postprandial, Insulin-Independent Activator of Hepatic Protein and Glycogen Synthesis
Kir, S., Beddow, S. A., Samuel, V. T., Miller, P., Previs, S. F., Suino-Powell, K., Xu, H. E., Shulman, G. I., Kliewer, S. A., & Mangelsdorf, D. J. (2011) · Science
Fibroblast Growth Factor ResearchMetabolism, Diabetes, and Cancer
Cited by 637
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Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment
Priller, J., Flügel, A., Wehner, T., Boentert, M., Haas, C. A., Prinz, M., Fernández-Klett, F., Prass, K., Bechmann, I., de Boer, B. A., et al. (2001) · Nature Medicine
Virus-based gene therapy researchBarrier Structure and Function Studies
Cited by 637
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A synaptic trek to autism
Bourgeron, T. (2009) · Current Opinion in Neurobiology
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 637
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Genomic and personalized medicine: foundations and applications
Ginsburg, G. S., & Willard, H. F. (2009) · Translational Research
Genomics and Rare DiseasesPharmacogenetics and Drug Metabolism
Cited by 637
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Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development
Wess, J., Eglen, R. M., & Gautam, D. (2007) · Nature Reviews Drug Discovery
Receptor Mechanisms and SignalingNeuroscience and Neuropharmacology Research
Cited by 637
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Collagen-based cell migration models in vitro and in vivo
Wolf, K., Alexander, S., Schacht, V., Coussens, L. M., von Andrian, U. H., van Rheenen, J., Deryugina, E., & Friedl, P. (2009) · Seminars in Cell & Developmental Biology
Cellular Mechanics and InteractionsCollagen: Extraction and Characterization
Cited by 637
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Oxidative Stress, Molecular Inflammation and Sarcopenia
Meng, S.-J., & Yu, L.-J. (2010) · International Journal of Molecular Sciences
Muscle Physiology and DisordersNutrition and Health in Aging
Cited by 637
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USP10 Regulates p53 Localization and Stability by Deubiquitinating p53
Yuan, J., Luo, K., Zhang, L., Cheville, J. C., & Lou, Z. (2010) · Cell
Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways
Cited by 637
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An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics
Angelidis, I., Simon, L. M., Fernandez, I. E., Strunz, M., Mayr, C. H., Greiffo, F. R., Tsitsiridis, G., Ansari, M., Graf, E., Strom, T.-M., et al. (2019) · Nature Communications
Single-cell and spatial transcriptomicsGenetics, Aging, and Longevity in Model Organisms
Cited by 637
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Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains
Cuddapah, S., Jothi, R., Schones, D. E., Roh, T.-Y., Cui, K., & Zhao, K. (2009) · Genome Research
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 637
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Independent Regulation of Collagenase, 72-kDa Progelatinase, and Metalloendoproteinase Inhibitor Expression in Human Fibroblasts by Transforming Growth Factor-β
Overall, C. M., Wrana, J. L., & Sodek, J. (1989) · Journal of Biological Chemistry
Protease and Inhibitor MechanismsTGF-β signaling in diseases
Cited by 636
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The major genetic risk factor for severe COVID-19 is inherited from Neanderthals
Zeberg, H., & Pääbo, S. (2020) · Nature
Genetic Associations and EpidemiologySARS-CoV-2 and COVID-19 Research
Cited by 636
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Energy Metabolic Phenotype of the Cardiomyocyte During Development, Differentiation, and Postnatal Maturation
Lopaschuk, G. D., & Jaswal, J. S. (2010) · Journal of Cardiovascular Pharmacology
Congenital heart defects researchCardiovascular Function and Risk Factors
Cited by 636
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Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?
Sfeir, A., & Symington, L. S. (2015) · Trends in Biochemical Sciences
DNA Repair MechanismsCRISPR and Genetic Engineering
Cited by 636
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Senescent cells as a source of inflammatory factors for tumor progression
Davalos, A. R., Coppe, J.-P., Campisi, J., & Desprez, P.-Y. (2010) · Cancer and Metastasis Reviews
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 636
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Circular RNA (circRNA) in Alzheimer’s disease (AD)
Lukiw, W. J. (2013) · Frontiers in Genetics
Circular RNAs in diseasesAlzheimer's disease research and treatments
Cited by 636
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Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering
Billingsley, M. M., Singh, N., Ravikumar, P., Zhang, R., June, C. H., & Mitchell, M. J. (2020) · Nano Letters
RNA Interference and Gene DeliveryCAR-T cell therapy research
Cited by 636
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Highly Expressed Genes in Yeast Evolve Slowly
Pál, C., Papp, B., & Hurst, L. D. (2001) · Genetics
Evolution and Genetic DynamicsFungal and yeast genetics research
Cited by 635
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Mitophagy in human health, ageing and disease
Picca, A., Faitg, J., Auwerx, J., Ferrucci, L., & D’Amico, D. (2023) · Nature Metabolism
Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms
Cited by 635
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Regulation of prefrontal cortex myelination by the microbiota
Hoban, A. E., Stilling, R. M., Ryan, F. J., Shanahan, F., Dinan, T. G., Claesson, M. J., Clarke, G., & Cryan, J. F. (2016) · Translational Psychiatry
Gut microbiota and healthNeurogenesis and neuroplasticity mechanisms
Cited by 635
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Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism
Sette, A., & Sidney, J. (1999) · Immunogenetics
vaccines and immunoinformatics approachesImmunotherapy and Immune Responses
Cited by 635
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Aging and neurodegeneration are associated with increased mutations in single human neurons
Lodato, M. A., Rodin, R. E., Bohrson, C. L., Coulter, M. E., Barton, A. R., Kwon, M., Sherman, M. A., Vitzthum, C. M., Luquette, L. J., Yandava, C. N., et al. (2018) · Science
Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics
Cited by 635
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Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy
Wright, G. L., Mayer Grob, B., Haley, C., Grossman, K., Newhall, K., Petrylak, D., Troyer, J., Konchuba, A., Schellhammer, P. F., & Moriarty, R. (1996) · Urology
Prostate Cancer Treatment and ResearchProstate Cancer Diagnosis and Treatment
Cited by 635
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Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomics
Schneekloth, A. R., Pucheault, M., Tae, H. S., & Crews, C. M. (2008) · Bioorganic & Medicinal Chemistry Letters
Protein Degradation and InhibitorsProstate Cancer Treatment and Research
Cited by 635
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