Most cited biochemistry, genetics and molecular biology papers
- Verified
Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians
Sato, Y., Atarashi, K., Plichta, D. R., Arai, Y., Sasajima, S., Kearney, S. M., Suda, W., Takeshita, K., Sasaki, T., Okamoto, S., et al. (2021) · Nature
Gut microbiota and healthSteroid Chemistry and Biochemistry
Cited by 632
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Calorie restriction extends yeast life span by lowering the level of NADH
Lin, S.-J., Ford, E., Haigis, M., Liszt, G., & Guarente, L. (2004) · Genes & Development
Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine
Cited by 632
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Gastrointestinal microbiota in children with autism in Slovakia
Tomova, A., Husarova, V., Lakatosova, S., Bakos, J., Vlkova, B., Babinska, K., & Ostatnikova, D. (2015) · Physiology & Behavior
Gut microbiota and healthAutism Spectrum Disorder Research
Cited by 632
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Endothelial Progenitor Cells Control the Angiogenic Switch in Mouse Lung Metastasis
Gao, D., Nolan, D. J., Mellick, A. S., Bambino, K., McDonnell, K., & Mittal, V. (2008) · Science
Angiogenesis and VEGF in CancerCancer Cells and Metastasis
Cited by 632
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Revealing the vectors of cellular identity with single-cell genomics
Wagner, A., Regev, A., & Yosef, N. (2016) · Nature Biotechnology
Single-cell and spatial transcriptomicsGene Regulatory Network Analysis
Cited by 632
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Multilineage Transcriptional Priming and Determination of Alternate Hematopoietic Cell Fates
Laslo, P., Spooner, C. J., Warmflash, A., Lancki, D. W., Lee, H.-J., Sciammas, R., Gantner, B. N., Dinner, A. R., & Singh, H. (2006) · Cell
Gene Regulatory Network AnalysisHematopoietic Stem Cell Transplantation
Cited by 632
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PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation
Lin, Q., Li, S., Jiang, N., Shao, X., Zhang, M., Jin, H., Zhang, Z., Shen, J., Zhou, Y., Zhou, W., et al. (2019) · Redox Biology
Autophagy in Disease and TherapyAcute Kidney Injury Research
Cited by 632
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Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer
Shu, S., Lin, C. Y., He, H. H., Witwicki, R. M., Tabassum, D. P., Roberts, J. M., Janiszewska, M., Jin Huh, S., Liang, Y., Ryan, J., et al. (2016) · Nature
Protein Degradation and InhibitorsChromatin Remodeling and Cancer
Cited by 632
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Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors
Kwon, J., Lee, S.-R., Yang, K.-S., Ahn, Y., Kim, Y. J., Stadtman, E. R., & Rhee, S. G. (2004) · Proceedings of the National Academy of Sciences
Redox biology and oxidative stressPI3K/AKT/mTOR signaling in cancer
Cited by 631
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HIF-1 as a target for drug development
Giaccia, A., Siim, B. G., & Johnson, R. S. (2003) · Nature Reviews Drug Discovery
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 631
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Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits
Brandl, K., Plitas, G., Mihu, C. N., Ubeda, C., Jia, T., Fleisher, M., Schnabl, B., DeMatteo, R. P., & Pamer, E. G. (2008) · Nature
Gut microbiota and healthAntibiotic Resistance in Bacteria
Cited by 631
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The role of TGF-β/SMAD4 signaling in cancer
Zhao, M., Mishra, L., & Deng, C.-X. (2018) · International Journal of Biological Sciences
TGF-β signaling in diseasesSignaling Pathways in Disease
Cited by 631
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Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase
LINDSTEDT, S. (1992) · The Lancet
Metabolism and Genetic DisordersPorphyrin Metabolism and Disorders
Cited by 631
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Mechanical compression drives cancer cells toward invasive phenotype
Tse, J. M., Cheng, G., Tyrrell, J. A., Wilcox-Adelman, S. A., Boucher, Y., Jain, R. K., & Munn, L. L. (2012) · Proceedings of the National Academy of Sciences
Cellular Mechanics and InteractionsCancer Cells and Metastasis
Cited by 631
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Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario
Chipuk, J. E., Bouchier-Hayes, L., & Green, D. R. (2006) · Cell Death & Differentiation
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 631
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The immune epitope database 2.0
Vita, R., Zarebski, L., Greenbaum, J. A., Emami, H., Hoof, I., Salimi, N., Damle, R., Sette, A., & Peters, B. (2010) · Nucleic Acids Research
vaccines and immunoinformatics approachesImmunotherapy and Immune Responses
Cited by 631
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Transcriptional activation and nuclear targeting signals of the human androgen receptor.
Simental, J. A., Sar, M., Lane, M. V., French, F. S., & Wilson, E. M. (1991) · Journal of Biological Chemistry
Estrogen and related hormone effectsProstate Cancer Treatment and Research
Cited by 631
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Cellular senescence: a key therapeutic target in aging and diseases
Zhang, L., Pitcher, L. E., Yousefzadeh, M. J., Niedernhofer, L. J., Robbins, P. D., & Zhu, Y. (2022) · Journal of Clinical Investigation
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 631
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Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair
Auer, T. O., Duroure, K., De Cian, A., Concordet, J.-P., & Del Bene, F. (2014) · Genome Research
CRISPR and Genetic EngineeringZebrafish Biomedical Research Applications
Cited by 631
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Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation
Parrinello, S., Coppe, J.-P., Krtolica, A., & Campisi, J. (2005) · Journal of Cell Science
Telomeres, Telomerase, and SenescenceTGF-β signaling in diseases
Cited by 631
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Implication of Trimethylamine N-Oxide (TMAO) in Disease: Potential Biomarker or New Therapeutic Target
Janeiro, M., Ramírez, M., Milagro, F., Martínez, J., & Solas, M. (2018) · Nutrients
Gut microbiota and healthPolyamine Metabolism and Applications
Cited by 631
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THE SMALL NUCLEOLAR RNAs
Maxwell, E., & Fournier, M. (1995) · Annual Review of Biochemistry
Nuclear Structure and FunctionRNA and protein synthesis mechanisms
Cited by 631
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Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells
Xian, L., Wu, X., Pang, L., Lou, M., Rosen, C. J., Qiu, T., Crane, J., Frassica, F., Zhang, L., Rodriguez, J. P., et al. (2012) · Nature Medicine
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 631
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Regulated necrosis: disease relevance and therapeutic opportunities
Conrad, M., Angeli, J. P. F., Vandenabeele, P., & Stockwell, B. R. (2016) · Nature Reviews Drug Discovery
Cell death mechanisms and regulationFerroptosis and cancer prognosis
Cited by 630
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