Most cited biochemistry, genetics and molecular biology papers
- Verified
Reactive Oxygen Species in the Regulation of Synaptic Plasticity and Memory
Massaad, C. A., & Klann, E. (2011) · Antioxidants & Redox Signaling
Redox biology and oxidative stressNeuroscience and Neuropharmacology Research
Cited by 635
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AlphaFold and Implications for Intrinsically Disordered Proteins
Ruff, K. M., & Pappu, R. V. (2021) · Journal of Molecular Biology
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 635
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RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer
Wolfe, A. L., Singh, K., Zhong, Y., Drewe, P., Rajasekhar, V. K., Sanghvi, V. R., Mavrakis, K. J., Jiang, M., Roderick, J. E., Van der Meulen, J., et al. (2014) · Nature
RNA and protein synthesis mechanismsDNA and Nucleic Acid Chemistry
Cited by 635
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Decontamination of ambient RNA in single-cell RNA-seq with DecontX
Yang, S., Corbett, S. E., Koga, Y., Wang, Z., Johnson, W. E., Yajima, M., & Campbell, J. D. (2020) · Genome Biology
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 635
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In Silico Labeling: Predicting Fluorescent Labels in Unlabeled Images
Christiansen, E. M., Yang, S. J., Ando, D. M., Javaherian, A., Skibinski, G., Lipnick, S., Mount, E., O’Neil, A., Shah, K., Lee, A. K., et al. (2018) · Cell
Cell Image Analysis TechniquesAdvanced Fluorescence Microscopy Techniques
Cited by 635
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Nuclear Factor (NF)-κB–regulated X-chromosome–linked iap Gene Expression Protects Endothelial Cells from Tumor Necrosis Factor α–induced Apoptosis
Stehlik, C., de Martin, R., Kumabashiri, I., Schmid, J. A., Binder, B. R., & Lipp, J. (1998) · The Journal of Experimental Medicine
NF-κB Signaling PathwaysCell death mechanisms and regulation
Cited by 635
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Current approaches and challenges for the metabolite profiling of complex natural extracts
Wolfender, J.-L., Marti, G., Thomas, A., & Bertrand, S. (2015) · Journal of Chromatography A
Metabolomics and Mass Spectrometry StudiesChromatography in Natural Products
Cited by 635
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Searching for missing heritability: Designing rare variant association studies
Zuk, O., Schaffner, S. F., Samocha, K., Do, R., Hechter, E., Kathiresan, S., Daly, M. J., Neale, B. M., Sunyaev, S. R., & Lander, E. S. (2014) · Proceedings of the National Academy of Sciences
Genetic Associations and EpidemiologyGenomics and Rare Diseases
Cited by 635
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Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood
Lee, S. H., Yang, J., Goddard, M. E., Visscher, P. M., & Wray, N. R. (2012) · Bioinformatics
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 635
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Missing data and technical variability in single-cell RNA-sequencing experiments
Hicks, S. C., Townes, F. W., Teng, M., & Irizarry, R. A. (2018) · Biostatistics
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 635
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Tumour hypoxia causes DNA hypermethylation by reducing TET activity
Thienpont, B., Steinbacher, J., Zhao, H., D’Anna, F., Kuchnio, A., Ploumakis, A., Ghesquière, B., Van Dyck, L., Boeckx, B., Schoonjans, L., et al. (2016) · Nature
Epigenetics and DNA MethylationCancer, Hypoxia, and Metabolism
Cited by 635
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Language models enable zero-shot prediction of the effects of mutations on protein function
Meier, J., Rao, R., Verkuil, R., Liu, J., Sercu, T., & Rives, A. (2021) · bioRxiv (Cold Spring Harbor Laboratory)
Machine Learning in BioinformaticsProtein Structure and Dynamics
Cited by 635
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Transposable Elements, Epigenetics, and Genome Evolution
Fedoroff, N. V. (2012) · Science
Chromosomal and Genetic VariationsPlant Genetic and Mutation Studies
Cited by 634
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Comparison and evaluation of statistical error models for scRNA-seq
Choudhary, S., & Satija, R. (2022) · Genome Biology
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 634
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Organ aging signatures in the plasma proteome track health and disease
Oh, H. S.-H., Rutledge, J., Nachun, D., Pálovics, R., Abiose, O., Moran-Losada, P., Channappa, D., Urey, D. Y., Kim, K., Sung, Y. J., et al. (2023) · Nature
Genetics, Aging, and Longevity in Model OrganismsDementia and Cognitive Impairment Research
Cited by 634
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Adipose-specific deletion of autophagy-related gene 7 ( atg7 ) in mice reveals a role in adipogenesis
Zhang, Y., Goldman, S., Baerga, R., Zhao, Y., Komatsu, M., & Jin, S. (2009) · Proceedings of the National Academy of Sciences
Autophagy in Disease and TherapyAdipose Tissue and Metabolism
Cited by 634
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The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation
Hashizume, R., Fukuda, M., Maeda, I., Nishikawa, H., Oyake, D., Yabuki, Y., Ogata, H., & Ohta, T. (2001) · Journal of Biological Chemistry
Ubiquitin and proteasome pathwaysBRCA gene mutations in cancer
Cited by 634
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Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers
Kinsey, C. G., Camolotto, S. A., Boespflug, A. M., Guillen, K. P., Foth, M., Truong, A., Schuman, S. S., Shea, J. E., Seipp, M. T., Yap, J. T., et al. (2019) · Nature Medicine
Autophagy in Disease and TherapyProtein Kinase Regulation and GTPase Signaling
Cited by 634
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Gavage of Fecal Samples From Patients With Colorectal Cancer Promotes Intestinal Carcinogenesis in Germ-Free and Conventional Mice
Wong, S. H., Zhao, L., Zhang, X., Nakatsu, G., Han, J., Xu, W., Xiao, X., Kwong, T. N. Y., Tsoi, H., Wu, W. K. K., et al. (2017) · Gastroenterology
Gut microbiota and healthGenetic factors in colorectal cancer
Cited by 634
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Biosynthesis of fungal melanins and their importance for human pathogenic fungi
Langfelder, K., Streibel, M., Jahn, B., Haase, G., & Brakhage, A. A. (2003) · Fungal Genetics and Biology
Fungal and yeast genetics researchFungal Infections and Studies
Cited by 634
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Mechanism of oligonucleotide release from cationic liposomes.
Zelphati, O., & Szoka, F. C. (1996) · Proceedings of the National Academy of Sciences
RNA Interference and Gene DeliveryLipid Membrane Structure and Behavior
Cited by 634
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The gut microbiome and liver cancer: mechanisms and clinical translation
Yu, L.-X., & Schwabe, R. F. (2017) · Nature Reviews Gastroenterology & Hepatology
Gut microbiota and healthHepatocellular Carcinoma Treatment and Prognosis
Cited by 634
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CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences
Lin, Y., Cradick, T. J., Brown, M. T., Deshmukh, H., Ranjan, P., Sarode, N., Wile, B. M., Vertino, P. M., Stewart, F. J., & Bao, G. (2014) · Nucleic Acids Research
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 634
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Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR
Reaper, P. M., Griffiths, M. R., Long, J. M., Charrier, J.-D., MacCormick, S., Charlton, P. A., Golec, J. M. C., & Pollard, J. R. (2011) · Nature Chemical Biology
DNA Repair MechanismsPARP inhibition in cancer therapy
Cited by 633
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