Most cited biochemistry, genetics and molecular biology papers
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Chromosome conformation elucidates regulatory relationships in developing human brain
Won, H., de la Torre-Ubieta, L., Stein, J. L., Parikshak, N. N., Huang, J., Opland, C. K., Gandal, M. J., Sutton, G. J., Hormozdiari, F., Lu, D., et al. (2016) · Nature
Genomics and Chromatin DynamicsGenomic variations and chromosomal abnormalities
Cited by 584
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Siderophore-mediated signaling regulates virulence factor production in Pseudomonas aeruginosa
Lamont, I. L., Beare, P. A., Ochsner, U., Vasil, A. I., & Vasil, M. L. (2002) · Proceedings of the National Academy of Sciences
Bacterial Genetics and BiotechnologyBacterial biofilms and quorum sensing
Cited by 584
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Variation in alternative splicing across human tissues
Yeo, G., Holste, D., Kreiman, G., & Burge, C. B. (2004) · Genome Biology
RNA Research and SplicingRNA regulation and disease
Cited by 584
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Lysophosphatidic Acid, a Multifunctional Phospholipid Messenger
Moolenaar, W. H. (1995) · Journal of Biological Chemistry
Sphingolipid Metabolism and SignalingLipid metabolism and biosynthesis
Cited by 584
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Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
Sciacovelli, M., Gonçalves, E., Johnson, T. I., Zecchini, V. R., da Costa, A. S. H., Gaude, E., Drubbel, A. V., Theobald, S. J., Abbo, S. R., Tran, M. G. B., et al. (2016) · Nature
Cancer, Hypoxia, and MetabolismEpigenetics and DNA Methylation
Cited by 584
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Polysialic acid in the plasticity of the developing and adult vertebrate nervous system
Rutishauser, U. (2008) · Nature Reviews Neuroscience
Glycosylation and Glycoproteins ResearchNeurogenesis and neuroplasticity mechanisms
Cited by 584
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Sexual-dimorphism in human immune system aging
Márquez, E. J., Chung, C.-H., Marches, R., Rossi, R. J., Nehar-Belaid, D., Eroglu, A., Mellert, D. J., Kuchel, G. A., Banchereau, J., & Ucar, D. (2020) · Nature Communications
Genetics, Aging, and Longevity in Model OrganismsT-cell and B-cell Immunology
Cited by 584
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Mitochondrial diversity and the origins of African and European cattle
Bradley, D. G., MacHugh, D. E., Cunningham, P., & Loftus, R. T. (1996) · Proceedings of the National Academy of Sciences
Genetic and phenotypic traits in livestockForensic and Genetic Research
Cited by 584
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Targeting the Wnt/β-Catenin Pathway to Regulate Bone Formation in the Adult Skeleton
Baron, R., & Rawadi, G. (2007) · Endocrinology
Wnt/β-catenin signaling in development and cancerBone Metabolism and Diseases
Cited by 584
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Colonic Secretion of Water and Electrolytes Induced by Bile Acids: Perfusion Studies in Man
Mekhjian, H. S., Phillips, S. F., & Hofmann, A. F. (1971) · Journal of Clinical Investigation
Ion Transport and Channel RegulationDrug Transport and Resistance Mechanisms
Cited by 584
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Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize
Fukumura, D., & Jain, R. K. (2007) · Journal of Cellular Biochemistry
Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism
Cited by 584
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SOS Response Induction by ß-Lactams and Bacterial Defense Against Antibiotic Lethality
Miller, C., Thomsen, L. E., Gaggero, C., Mosseri, R., Ingmer, H., & Cohen, S. N. (2004) · Science
Bacterial Genetics and BiotechnologyDNA Repair Mechanisms
Cited by 584
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A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease
Brehme, M., Voisine, C., Rolland, T., Wachi, S., Soper, J. H., Zhu, Y., Orton, K., Villella, A., Garza, D., Vidal, M., et al. (2014) · Cell Reports
Heat shock proteins researchGenetics, Aging, and Longevity in Model Organisms
Cited by 584
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The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1
Chan, E. H. Y., Nousiainen, M., Chalamalasetty, R. B., Schäfer, A., Nigg, E. A., & Silljé, H. H. W. (2005) · Oncogene
Hippo pathway signaling and YAP/TAZProtein Kinase Regulation and GTPase Signaling
Cited by 584
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Antidiabetic Therapies Affect Risk of Pancreatic Cancer
Li, D., Yeung, S. J., Hassan, M. M., Konopleva, M., & Abbruzzese, J. L. (2009) · Gastroenterology
Metabolism, Diabetes, and CancerPancreatic and Hepatic Oncology Research
Cited by 584
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The Fos family of transcription factors and their role in tumourigenesis
Milde-Langosch, K. (2005) · European Journal of Cancer
Cancer Mechanisms and TherapyProtein Kinase Regulation and GTPase Signaling
Cited by 583
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Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer
Hon, G. C., Hawkins, R. D., Caballero, O. L., Lo, C., Lister, R., Pelizzola, M., Valsesia, A., Ye, Z., Kuan, S., Edsall, L. E., et al. (2012) · Genome Research
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 583
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Quantitative analysis of the packaging capacity of recombinant adeno-associated virus
Dong, J.-Y., Fan, P.-D., & Frizzell, R. A. (1996) · Human Gene Therapy
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 583
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Large-scale plasma proteomics comparisons through genetics and disease associations
Eldjarn, G. H., Ferkingstad, E., Lund, S. H., Helgason, H., Magnusson, O. T., Gunnarsdottir, K., Olafsdottir, T. A., Halldorsson, B. V., Olason, P. I., Zink, F., et al. (2023) · Nature
Genetic Associations and EpidemiologyBioinformatics and Genomic Networks
Cited by 583
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An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
Zanoni, I., Tan, Y., Di Gioia, M., Broggi, A., Ruan, J., Shi, J., Donado, C. A., Shao, F., Wu, H., Springstead, J. R., et al. (2016) · Science
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 583
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JNK Activity in Somatic Stem Cells Causes Loss of Tissue Homeostasis in the Aging Drosophila Gut
Biteau, B., Hochmuth, C. E., & Jasper, H. (2008) · Cell Stem Cell
Genetics, Aging, and Longevity in Model OrganismsDevelopmental Biology and Gene Regulation
Cited by 583
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Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake
Meslier, V., Laiola, M., Roager, H. M., De Filippis, F., Roume, H., Quinquis, B., Giacco, R., Mennella, I., Ferracane, R., Pons, N., et al. (2020) · Gut
Gut microbiota and healthNutritional Studies and Diet
Cited by 583
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Chromothripsis as an on-target consequence of CRISPR–Cas9 genome editing
Leibowitz, M. L., Papathanasiou, S., Doerfler, P. A., Blaine, L. J., Sun, L., Yao, Y., Zhang, C.-Z., Weiss, M. J., & Pellman, D. (2021) · Nature Genetics
CRISPR and Genetic EngineeringDNA Repair Mechanisms
Cited by 583
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Glutathione S-transferases as antioxidant defence agents confer pyrethroid resistance in Nilaparvata lugens
VONTAS, J. G., SMALL, G. J., & HEMINGWAY, J. (2001) · Biochemical Journal
Insect Resistance and GeneticsGlutathione Transferases and Polymorphisms
Cited by 583
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