Most cited biochemistry, genetics and molecular biology papers
- Verified
Human iPSC-Derived Oligodendrocyte Progenitor Cells Can Myelinate and Rescue a Mouse Model of Congenital Hypomyelination
Wang, S., Bates, J., Li, X., Schanz, S., Chandler-Militello, D., Levine, C., Maherali, N., Studer, L., Hochedlinger, K., Windrem, M., et al. (2013) · Cell Stem Cell
Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms
Cited by 586
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Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease
Gregor, M. F., & Hotamisligil, G. S. (2007) · Journal of Lipid Research
Endoplasmic Reticulum Stress and DiseaseAdipokines, Inflammation, and Metabolic Diseases
Cited by 586
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De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data
Grün, D., Muraro, M. J., Boisset, J.-C., Wiebrands, K., Lyubimova, A., Dharmadhikari, G., van den Born, M., van Es, J., Jansen, E., Clevers, H., et al. (2016) · Cell Stem Cell
Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation
Cited by 586
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Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy
Du, R., Huang, C., Liu, K., Li, X., & Dong, Z. (2021) · Molecular Cancer
Microtubule and mitosis dynamicsCancer Mechanisms and Therapy
Cited by 586
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Gut Microbiota and Cancer: From Pathogenesis to Therapy
Vivarelli, S., Salemi, R., Candido, S., Falzone, L., Santagati, M., Stefani, S., Torino, F., Banna, G. L., Tonini, G., & Libra, M. (2019) · Cancers
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 586
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The transcription factor NF-ATc is essential for cardiac valve formation
Ranger, A. M., Grusby, M. J., Hodge, M. R., Gravallese, E. M., de la Brousse, F. C., Hoey, T., Mickanin, C., Baldwin, H. S., & Glimcher, L. H. (1998) · Nature
Congenital heart defects researchSignaling Pathways in Disease
Cited by 586
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Statistical methods for analysis of high-throughput RNA interference screens
Birmingham, A., Selfors, L. M., Forster, T., Wrobel, D., Kennedy, C. J., Shanks, E., Santoyo-Lopez, J., Dunican, D. J., Long, A., Kelleher, D., et al. (2009) · Nature Methods
RNA Interference and Gene DeliveryGene expression and cancer classification
Cited by 586
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Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis
Deniaud, A., Sharaf el dein, O., Maillier, E., Poncet, D., Kroemer, G., Lemaire, C., & Brenner, C. (2008) · Oncogene
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 586
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Progressive Cactus is a multiple-genome aligner for the thousand-genome era
Armstrong, J., Hickey, G., Diekhans, M., Fiddes, I. T., Novak, A. M., Deran, A., Fang, Q., Xie, D., Feng, S., Stiller, J., et al. (2020) · Nature
Genomics and Phylogenetic StudiesGenome Rearrangement Algorithms
Cited by 586
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Role of receptor activator of nuclear factor-κB ligand and osteoprotegerin in bone cell biology
Hofbauer, L. C., & Heufelder, A. E. (2001) · Journal of Molecular Medicine
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 586
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Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth
Sun, Q., Chen, X., Ma, J., Peng, H., Wang, F., Zha, X., Wang, Y., Jing, Y., Yang, H., Chen, R., et al. (2011) · Proceedings of the National Academy of Sciences
Cancer, Hypoxia, and MetabolismPI3K/AKT/mTOR signaling in cancer
Cited by 586
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The role of lipoproteins in steroidogenesis and cholesterol metabolism in steroidogenic glands
GWYNNE, J. T., & STRAUSS, J. F. (1982) · Endocrine Reviews
Cholesterol and Lipid MetabolismSteroid Chemistry and Biochemistry
Cited by 586
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Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort
Qin, Y., Havulinna, A. S., Liu, Y., Jousilahti, P., Ritchie, S. C., Tokolyi, A., Sanders, J. G., Valsta, L., Brożyńska, M., Zhu, Q., et al. (2022) · Nature Genetics
Gut microbiota and healthGenetic Associations and Epidemiology
Cited by 586
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Mitochondrial Energetics in the Heart in Obesity-Related Diabetes
Boudina, S., Sena, S., Theobald, H., Sheng, X., Wright, J. J., Hu, X. X., Aziz, S., Johnson, J. I., Bugger, H., Zaha, V. G., et al. (2007) · Diabetes
Mitochondrial Function and PathologyCardiovascular Function and Risk Factors
Cited by 586
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Common genetic variation drives molecular heterogeneity in human iPSCs
Kilpinen, H., Goncalves, A., Leha, A., Afzal, V., Alasoo, K., Ashford, S., Bala, S., Bensaddek, D., Casale, F. P., Culley, O. J., et al. (2017) · Nature
Pluripotent Stem Cells ResearchGenetic Associations and Epidemiology
Cited by 586
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Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling
Adam, J., Hatipoglu, E., O'Flaherty, L., Ternette, N., Sahgal, N., Lockstone, H., Baban, D., Nye, E., Stamp, G. W., Wolhuter, K., et al. (2011) · Cancer Cell
Genomics, phytochemicals, and oxidative stressCancer, Hypoxia, and Metabolism
Cited by 585
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Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells
Jones, C. L., Stevens, B. M., D'Alessandro, A., Reisz, J. A., Culp-Hill, R., Nemkov, T., Pei, S., Khan, N., Adane, B., Ye, H., et al. (2018) · Cancer Cell
Cancer, Hypoxia, and MetabolismAcute Myeloid Leukemia Research
Cited by 585
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Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
Fleishman, S. J., Whitehead, T. A., Ekiert, D. C., Dreyfus, C., Corn, J. E., Strauch, E.-M., Wilson, I. A., & Baker, D. (2011) · Science
Protein Structure and DynamicsInfluenza Virus Research Studies
Cited by 585
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The fibronectin type III domain as a scaffold for novel binding proteins
Koide, A., Bailey, C. W., Huang, X., & Koide, S. (1998) · Journal of Molecular Biology
Protein Structure and DynamicsBiochemical and Structural Characterization
Cited by 585
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Rapid disuse and denervation atrophy involve transcriptional changes similar to those of muscle wasting during systemic diseases
Sacheck, J. M., Hyatt, J. K., Raffaello, A., Thomas Jagoe, R., Roy, R. R., Reggie Edgerton, V., Lecker, S. H., & Goldberg, A. L. (2007) · The FASEB Journal
Muscle Physiology and DisordersNutrition and Health in Aging
Cited by 585
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Review on Strategies and Technologies for Exosome Isolation and Purification
Chen, J., Li, P., Zhang, T., Xu, Z., Huang, X., Wang, R., & Du, L. (2022) · Frontiers in Bioengineering and Biotechnology
Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery
Cited by 585
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Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions
Mohammad, S., & Thiemermann, C. (2021) · Frontiers in Immunology
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 585
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Tumor adaptation and resistance to RAF inhibitors
Lito, P., Rosen, N., & Solit, D. B. (2013) · Nature Medicine
Melanoma and MAPK PathwaysLung Cancer Treatments and Mutations
Cited by 585
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Reversible compartmentalization of de novo purine biosynthetic complexes in living cells
An, S., Kumar, R., Sheets, E. D., & Benkovic, S. J. (2008) · Science
Biochemical and Molecular ResearchGout, Hyperuricemia, Uric Acid
Cited by 585
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