Most cited biochemistry, genetics and molecular biology papers
- Verified
miR-33 links SREBP-2 induction to repression of sterol transporters
Marquart, T. J., Allen, R. M., Ory, D. S., & Baldán, Á. (2010) · Proceedings of the National Academy of Sciences
Cholesterol and Lipid MetabolismMicroRNA in disease regulation
Cited by 562
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RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3
Dillon, C. P., Weinlich, R., Rodriguez, D. A., Cripps, J. G., Quarato, G., Gurung, P., Verbist, K. C., Brewer, T. L., Llambi, F., Gong, Y.-N., et al. (2014) · Cell
Cell death mechanisms and regulationNF-κB Signaling Pathways
Cited by 562
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Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
Hernando, E., Nahlé, Z., Juan, G., Diaz-Rodriguez, E., Alaminos, M., Hemann, M., Michel, L., Mittal, V., Gerald, W., Benezra, R., et al. (2004) · Nature
Microtubule and mitosis dynamicsCancer-related Molecular Pathways
Cited by 562
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MGnify: the microbiome analysis resource in 2020
Mitchell, A. L., Almeida, A., Beracochea, M., Boland, M., Burgin, J., Cochrane, G., Crusoe, M. R., Kale, V., Potter, S. C., Richardson, L. J., et al. (2019) · Nucleic Acids Research
Genomics and Phylogenetic StudiesScientific Computing and Data Management
Cited by 562
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A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses
Ripatti, S., Tikkanen, E., Orho-Melander, M., Havulinna, A. S., Silander, K., Sharma, A., Guiducci, C., Perola, M., Jula, A., Sinisalo, J., et al. (2010) · The Lancet
Genetic Associations and EpidemiologyNutrition, Genetics, and Disease
Cited by 562
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The binding cascade of SecB to SecA to SecYE mediates preprotein targeting to the E. coli plasma membrane
Hartl, F.-U., Lecker, S., Schiebel, E., Hendrick, J. P., & Wickner, W. (1990) · Cell
Bacterial Genetics and BiotechnologyHeat shock proteins research
Cited by 562
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Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism
Reitman, Z. J., & Yan, H. (2010) · JNCI Journal of the National Cancer Institute
Cancer, Hypoxia, and MetabolismGlioma Diagnosis and Treatment
Cited by 562
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Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS
Yao, Z., Yaeger, R., Rodrik-Outmezguine, V. S., Tao, A., Torres, N. M., Chang, M. T., Drosten, M., Zhao, H., Cecchi, F., Hembrough, T., et al. (2017) · Nature
Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling
Cited by 562
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Genome-Scale Imaging of the 3D Organization and Transcriptional Activity of Chromatin
Su, J.-H., Zheng, P., Kinrot, S. S., Bintu, B., & Zhuang, X. (2020) · Cell
Genomics and Chromatin DynamicsAdvanced Fluorescence Microscopy Techniques
Cited by 562
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Sequence, Structure, and Context Preferences of Human RNA Binding Proteins
Dominguez, D., Freese, P., Alexis, M. S., Su, A., Hochman, M., Palden, T., Bazile, C., Lambert, N. J., Van Nostrand, E. L., Pratt, G. A., et al. (2018) · Molecular Cell
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 562
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BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
Farnaby, W., Koegl, M., Roy, M. J., Whitworth, C., Diers, E., Trainor, N., Zollman, D., Steurer, S., Karolyi-Oezguer, J., Riedmueller, C., et al. (2019) · Nature Chemical Biology
Protein Degradation and InhibitorsChromatin Remodeling and Cancer
Cited by 562
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Plant terpenes: defense responses, phylogenetic analysis, regulation and clinical applications
Singh, B., & Sharma, R. A. (2015) · 3 Biotech
Plant biochemistry and biosynthesisPlant tissue culture and regeneration
Cited by 562
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ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade
Shen, J., Ju, Z., Zhao, W., Wang, L., Peng, Y., Ge, Z., Nagel, Z. D., Zou, J., Wang, C., Kapoor, P., et al. (2018) · Nature Medicine
Chromatin Remodeling and CancerCancer Immunotherapy and Biomarkers
Cited by 562
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Vitamin A metabolism: An update
D’Ambrosio, D. N., Clugston, R. D., & Blaner, W. S. (2011) · Nutrients
Retinoids in leukemia and cellular processesCholesterol and Lipid Metabolism
Cited by 562
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Mammalian NET-Seq Reveals Genome-wide Nascent Transcription Coupled to RNA Processing
Nojima, T., Gomes, T., Grosso, A. R. F., Kimura, H., Dye, M. J., Dhir, S., Carmo-Fonseca, M., & Proudfoot, N. J. (2015) · Cell
Genomics and Chromatin DynamicsRNA Research and Splicing
Cited by 562
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The genome of a Late Pleistocene human from a Clovis burial site in western Montana
Rasmussen, M., Anzick, S. L., Waters, M. R., Skoglund, P., DeGiorgio, M., Stafford, T. W., Rasmussen, S., Moltke, I., Albrechtsen, A., Doyle, S. M., et al. (2014) · Nature
Forensic and Genetic ResearchPleistocene-Era Hominins and Archaeology
Cited by 562
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X-linked adrenoleukodystrophy (X-ALD): clinical presentation and guidelines for diagnosis, follow-up and management
Engelen, M., Kemp, S., de Visser, M., van Geel, B. M., Wanders, R. J., Aubourg, P., & Poll-The, B. (2012) · Orphanet Journal of Rare Diseases
Metabolism and Genetic DisordersLysosomal Storage Disorders Research
Cited by 562
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Increased Activation of the Mammalian Target of Rapamycin Pathway in Liver and Skeletal Muscle of Obese Rats: Possible Involvement in Obesity-Linked Insulin Resistance
Khamzina, L., Veilleux, A., Bergeron, S., & Marette, A. (2005) · Endocrinology
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 562
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Sequence locally, think globally: the Darwin Tree of Life Project
The Darwin Tree of Life Project Consortium, Blaxter, M., Mieszkowska, N., Di Palma, F., Holland, P., Durbin, R., Richards, T., Berriman, M., Kersey, P., Hollingsworth, P., et al. (2022) · Proceedings of the National Academy of Sciences
Genomics and Phylogenetic StudiesEnvironmental DNA in Biodiversity Studies
Cited by 562
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Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells
Lewis, C. A., Parker, S. J., Fiske, B. P., McCloskey, D., Gui, D. Y., Green, C. R., Vokes, N. I., Feist, A. M., Vander Heiden, M. G., & Metallo, C. M. (2014) · Molecular Cell
Redox biology and oxidative stressCancer, Hypoxia, and Metabolism
Cited by 562
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Direct Conversion of Fibroblasts to Neurons by Reprogramming PTB-Regulated MicroRNA Circuits
Xue, Y., Ouyang, K., Huang, J., Zhou, Y., Ouyang, H., Li, H., Wang, G., Wu, Q., Wei, C., Bi, Y., et al. (2013) · Cell
Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms
Cited by 562
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Relief of profound feedback inhibition of mitogenic signaling by RAF inhibitors attenuates their activity in BRAFV600E melanomas
Lito, P., Pratilas, C. A., Joseph, E. W., Tadi, M., Halilovic, E., Zubrowski, M., Huang, A., Wong, W. L., Callahan, M. K., Merghoub, T., et al. (2012) · Cancer Cell
Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling
Cited by 562
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The Human Glucocorticoid Receptor β Isoform
Oakley, R. H., Sar, M., & Cidlowski, J. A. (1996) · Journal of Biological Chemistry
Estrogen and related hormone effectsRNA Research and Splicing
Cited by 562
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Identification of senescent cells in the bone microenvironment
Farr, J. N., Fraser, D. G., Wang, H., Jaehn, K., Ogrodnik, M. B., Weivoda, M. M., Drake, M. T., Tchkonia, T., LeBrasseur, N. K., Kirkland, J. L., et al. (2016) · Journal of Bone and Mineral Research
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 562
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