Most cited biochemistry, genetics and molecular biology papers
- Verified
Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes
Lang, P., Gesbert, F., Delespine‐Carmagnat, M., Stancou, R., Pouchelet, M., & Bertoglio, J. (1996) · The EMBO Journal
Protein Kinase Regulation and GTPase SignalingReceptor Mechanisms and Signaling
Cited by 558
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Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation
Prendergast, G. C., Lawe, D., & Ziff, E. B. (1991) · Cell
Genomics and Chromatin DynamicsCancer-related Molecular Pathways
Cited by 558
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Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival
Fung, C., Lock, R., Gao, S., Salas, E., & Debnath, J. (2008) · Molecular Biology of the Cell
Autophagy in Disease and TherapyCell death mechanisms and regulation
Cited by 558
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History of CRISPR-Cas from Encounter with a Mysterious Repeated Sequence to Genome Editing Technology
Ishino, Y., Krupovic, M., & Forterre, P. (2018) · Journal of Bacteriology
CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology
Cited by 558
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Autophagy Protects against Sindbis Virus Infection of the Central Nervous System
Orvedahl, A., MacPherson, S., Sumpter, R., Tallóczy, Z., Zou, Z., & Levine, B. (2010) · Cell Host & Microbe
Autophagy in Disease and TherapyMosquito-borne diseases and control
Cited by 558
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Diabetes and gender
Gale, E. A. M., & Gillespie, K. M. (2001) · Diabetologia
Diabetes and associated disordersSex and Gender in Healthcare
Cited by 558
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PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer
Dupuy, F., Tabariès, S., Andrzejewski, S., Dong, Z., Blagih, J., Annis, M. G., Omeroglu, A., Gao, D., Leung, S., Amir, E., et al. (2015) · Cell Metabolism
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 558
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Both alpha- and beta-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors
Luetje, C., & Patrick, J. (1991) · The Journal of Neuroscience
Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research
Cited by 558
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GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.
Laverriere, A. C., MacNeill, C., Mueller, C., Poelmann, R. E., Burch, J. B., & Evans, T. (1994) · Journal of Biological Chemistry
Congenital heart defects researchDevelopmental Biology and Gene Regulation
Cited by 558
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Endogenous hydrogen sulfide production is essential for dietary restriction benefits
Hine, C., Harputlugil, E., Zhang, Y., Ruckenstuhl, C., Lee, B. C., Brace, L., Longchamp, A., Treviño-Villarreal, J. H., Mejia, P., Ozaki, C. K., et al. (2015) · Cell
Sulfur Compounds in BiologyGenetics, Aging, and Longevity in Model Organisms
Cited by 558
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MCOLN1 is a ROS sensor in lysosomes that regulates autophagy
Zhang, X., Cheng, X., Yu, L., Yang, J., Calvo, R., Patnaik, S., Hu, X., Gao, Q., Yang, M., Lawas, M., et al. (2016) · Nature Communications
Calcium signaling and nucleotide metabolismAutophagy in Disease and Therapy
Cited by 558
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Varenicline Is a Partial Agonist at α4β2 and a Full Agonist at α7 Neuronal Nicotinic Receptors
Mihalak, K. B., Carroll, F. I., & Luetje, C. W. (2006) · Molecular Pharmacology
Nicotinic Acetylcholine Receptors StudySmoking Behavior and Cessation
Cited by 558
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Coordination of Growth Rate, Cell Cycle, Stress Response, and Metabolic Activity in Yeast
Brauer, M. J., Huttenhower, C., Airoldi, E. M., Rosenstein, R., Matese, J. C., Gresham, D., Boer, V. M., Troyanskaya, O. G., & Botstein, D. (2008) · Molecular Biology of the Cell
Fungal and yeast genetics researchGene Regulatory Network Analysis
Cited by 558
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Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis
Greninger, A. L., Naccache, S. N., Federman, S., Yu, G., Mbala, P., Bres, V., Stryke, D., Bouquet, J., Somasekar, S., Linnen, J. M., et al. (2015) · Genome Medicine
Genomics and Phylogenetic StudiesViral Infections and Outbreaks Research
Cited by 558
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Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma
Tardito, S., Oudin, A., Ahmed, S. U., Fack, F., Keunen, O., Zheng, L., Miletic, H., Sakariassen, P. Ø., Weinstock, A., Wagner, A., et al. (2015) · Nature Cell Biology
Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism
Cited by 557
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Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism
Bota, D. A., & Davies, K. J. A. (2002) · Nature Cell Biology
Heat shock proteins researchMitochondrial Function and Pathology
Cited by 557
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Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test
Lionel, A. C., Costain, G., Monfared, N., Walker, S., Reuter, M. S., Hosseini, S. M., Thiruvahindrapuram, B., Merico, D., Jobling, R., Nalpathamkalam, T., et al. (2018) · Genetics in Medicine
Genomics and Rare DiseasesPrenatal Screening and Diagnostics
Cited by 557
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Coupling of bone resorption and formation by RANKL reverse signalling
Ikebuchi, Y., Aoki, S., Honma, M., Hayashi, M., Sugamori, Y., Khan, M., Kariya, Y., Kato, G., Tabata, Y., Penninger, J. M., et al. (2018) · Nature
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 557
- Verified
Coenzyme Q 10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects
Matthews, R. T., Yang, L., Browne, S., Baik, M., & Beal, M. F. (1998) · Proceedings of the National Academy of Sciences
Coenzyme Q10 studies and effectsMitochondrial Function and Pathology
Cited by 557
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deFuse: An Algorithm for Gene Fusion Discovery in Tumor RNA-Seq Data
McPherson, A., Hormozdiari, F., Zayed, A., Giuliany, R., Ha, G., Sun, M. G. F., Griffith, M., Heravi Moussavi, A., Senz, J., Melnyk, N., et al. (2011) · PLoS Computational Biology
Cancer Genomics and DiagnosticsGenomics and Phylogenetic Studies
Cited by 557
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A Disulfide Relay System in the Intermembrane Space of Mitochondria that Mediates Protein Import
Mesecke, N., Terziyska, N., Kozany, C., Baumann, F., Neupert, W., Hell, K., & Herrmann, J. M. (2005) · Cell
Mitochondrial Function and PathologyRedox biology and oxidative stress
Cited by 557
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Deep Learning Automates the Quantitative Analysis of Individual Cells in Live-Cell Imaging Experiments
Van Valen, D. A., Kudo, T., Lane, K. M., Macklin, D. N., Quach, N. T., DeFelice, M. M., Maayan, I., Tanouchi, Y., Ashley, E. A., & Covert, M. W. (2016) · PLoS Computational Biology
Cell Image Analysis TechniquesAdvanced Neural Network Applications
Cited by 557
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A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
Ng, K. P., Hillmer, A. M., Chuah, C. T. H., Juan, W. C., Ko, T. K., Teo, A. S. M., Ariyaratne, P. N., Takahashi, N., Sawada, K., Fei, Y., et al. (2012) · Nature Medicine
Cell death mechanisms and regulationLung Cancer Treatments and Mutations
Cited by 557
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Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway
Mo, J.-S., Meng, Z., Kim, Y. C., Park, H. W., Hansen, C. G., Kim, S., Lim, D.-S., & Guan, K.-L. (2015) · Nature Cell Biology
Hippo pathway signaling and YAP/TAZMetabolism, Diabetes, and Cancer
Cited by 557
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