Most cited biochemistry, genetics and molecular biology papers
- Verified
Circulating microRNAs as novel biomarkers for diabetes mellitus
Guay, C., & Regazzi, R. (2013) · Nature Reviews Endocrinology
MicroRNA in disease regulationExtracellular vesicles in disease
Cited by 563
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Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone.
Laurin, N., Brown, J. P., Morissette, J., & Raymond, V. (2002) · The American Journal of Human Genetics
Bone Metabolism and DiseasesAlkaline Phosphatase Research Studies
Cited by 563
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Hypoxia and drug resistance
Teicher, B. A. (1994) · Cancer and Metastasis Reviews
Cancer, Hypoxia, and MetabolismBioactive Compounds and Antitumor Agents
Cited by 563
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Molecular mechanisms of ATP secretion during immunogenic cell death
Martins, I., Wang, Y., Michaud, M., Ma, Y., Sukkurwala, A. Q., Shen, S., Kepp, O., Métivier, D., Galluzzi, L., Perfettini, J.-L., et al. (2014) · Cell Death & Differentiation
Cell death mechanisms and regulationAdenosine and Purinergic Signaling
Cited by 563
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Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer
Liang, J., Nagahashi, M., Kim, E. Y., Harikumar, K. B., Yamada, A., Huang, W.-C., Hait, N. C., Allegood, J. C., Price, M. M., Avni, D., et al. (2013) · Cancer Cell
Sphingolipid Metabolism and SignalingCytokine Signaling Pathways and Interactions
Cited by 563
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A High-Efficiency System for the Generation and Study of Human Induced Pluripotent Stem Cells
Maherali, N., Ahfeldt, T., Rigamonti, A., Utikal, J., Cowan, C., & Hochedlinger, K. (2008) · Cell Stem Cell
Pluripotent Stem Cells ResearchMesenchymal stem cell research
Cited by 563
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Molecular architecture of the developing mouse brain
La Manno, G., Siletti, K., Furlan, A., Gyllborg, D., Vinsland, E., Mossi Albiach, A., Mattsson Langseth, C., Khven, I., Lederer, A. R., Dratva, L. M., et al. (2021) · Nature
Single-cell and spatial transcriptomicsNeurogenesis and neuroplasticity mechanisms
Cited by 563
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Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions
Lopes, M., Foiani, M., & Sogo, J. M. (2006) · Molecular Cell
DNA Repair MechanismsFungal and yeast genetics research
Cited by 563
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Abnormal angiogenesis but intact hematopoietic potential in TGF‐β type I receptor‐deficient mice
Larsson, J., Goumans, M., Sjöstrand, L. J., van Rooijen, M. A., Ward, D., Levéen, P., Xu, X., ten Dijke, P., Mummery, C. L., & Karlsson, S. (2001) · The EMBO Journal
TGF-β signaling in diseasesAngiogenesis and VEGF in Cancer
Cited by 563
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Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation
Berkel, S., Marshall, C. R., Weiss, B., Howe, J., Roeth, R., Moog, U., Endris, V., Roberts, W., Szatmari, P., Pinto, D., et al. (2010) · Nature Genetics
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 563
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Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts
Nicholls, D. G., & Ward, M. W. (2000) · Trends in Neurosciences
Mitochondrial Function and PathologyCell death mechanisms and regulation
Cited by 563
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Dosage‐sensitive requirement for mouse Dll4 in artery development
Duarte, A., Hirashima, M., Benedito, R., Trindade, A., Diniz, P., Bekman, E., Costa, L., Henrique, D., & Rossant, J. (2004) · Genes & Development
Developmental Biology and Gene RegulationAngiogenesis and VEGF in Cancer
Cited by 563
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Ferroptosis Inhibition: Mechanisms and Opportunities
Angeli, J. P. F., Shah, R., Pratt, D. A., & Conrad, M. (2017) · Trends in Pharmacological Sciences
Ferroptosis and cancer prognosisCell death mechanisms and regulation
Cited by 563
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Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation
Lee, J. V., Carrer, A., Shah, S., Snyder, N. W., Wei, S., Venneti, S., Worth, A. J., Yuan, Z.-F., Lim, H.-W., Liu, S., et al. (2014) · Cell Metabolism
Cancer, Lipids, and MetabolismCancer, Hypoxia, and Metabolism
Cited by 563
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Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets
Bedford, L., Lowe, J., Dick, L. R., Mayer, R. J., & Brownell, J. E. (2011) · Nature Reviews Drug Discovery
Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors
Cited by 563
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Gut microbiota dysbiosis in patients with non-alcoholic fatty liver disease
Shen, F., Zheng, R.-D., Sun, X.-Q., Ding, W.-J., Wang, X.-Y., & Fan, J.-G. (2017) · Hepatobiliary & Pancreatic Diseases International
Gut microbiota and healthLiver Disease Diagnosis and Treatment
Cited by 563
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Gut microbe-generated metabolite trimethylamine-N-oxide as cardiovascular risk biomarker: a systematic review and dose-response meta-analysis
Schiattarella, G. G., Sannino, A., Toscano, E., Giugliano, G., Gargiulo, G., Franzone, A., Trimarco, B., Esposito, G., & Perrino, C. (2017) · European Heart Journal
Gut microbiota and healthNutritional Studies and Diet
Cited by 563
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Relationship between the Heat Tolerance of Photosynthesis and the Thermal Stability of Rubisco Activase in Plants from Contrasting Thermal Environments
Salvucci, M. E., & Crafts-Brandner, S. J. (2004) · Plant Physiology
Photosynthetic Processes and MechanismsPlant Stress Responses and Tolerance
Cited by 563
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Autophagy balances inflammation in innate immunity
Deretic, V., & Levine, B. (2018) · Autophagy
Autophagy in Disease and TherapyInflammasome and immune disorders
Cited by 563
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Nonclassical IL-1β Secretion Stimulated by P2X7 Receptors Is Dependent on Inflammasome Activation and Correlated with Exosome Release in Murine Macrophages
Qu, Y., Franchi, L., Nunez, G., & Dubyak, G. R. (2007) · The Journal of Immunology
Inflammasome and immune disordersAdenosine and Purinergic Signaling
Cited by 563
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The genetic code is one in a million
Freeland, S. J., & Hurst, L. D. (1998) · Journal of Molecular Evolution
RNA and protein synthesis mechanismsEvolution and Genetic Dynamics
Cited by 563
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Obese-type gut microbiota induce neurobehavioral changes in the absence of obesity
Bruce-Keller, A. J., Salbaum, J. M., Luo, M., Blanchard, E., Taylor, C. M., Welsh, D. A., & Berthoud, H.-R. (2015) · Biological Psychiatry
Gut microbiota and healthTryptophan and brain disorders
Cited by 563
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Oxidative Stress Increased Respiration and Generation of Reactive Oxygen Species, Resulting in ATP Depletion, Opening of Mitochondrial Permeability Transition, and Programmed Cell Death
Tiwari, B. S., Belenghi, B., & Levine, A. (2002) · Plant Physiology
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 563
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Gene therapy for Wiskott-Aldrich syndrome–long-term efficacy and genotoxicity
Braun, C. J., Boztug, K., Paruzynski, A., Witzel, M., Schwarzer, A., Rothe, M., Modlich, U., Beier, R., Göhring, G., Steinemann, D., et al. (2014) · Science Translational Medicine
Virus-based gene therapy researchImmunodeficiency and Autoimmune Disorders
Cited by 562
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