Most cited biochemistry, genetics and molecular biology papers
- Verified
Identification of senescent cells in the bone microenvironment
Farr, J. N., Fraser, D. G., Wang, H., Jaehn, K., Ogrodnik, M. B., Weivoda, M. M., Drake, M. T., Tchkonia, T., LeBrasseur, N. K., Kirkland, J. L., et al. (2016) · Journal of Bone and Mineral Research
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 562
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Concise review: dissecting a discrepancy in the literature: do mesenchymal stem cells support or suppress tumor growth?
Klopp, A. H., Gupta, A., Spaeth, E., Andreeff, M., & Marini, F. (2011) · Stem Cells
Mesenchymal stem cell researchCancer Cells and Metastasis
Cited by 562
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Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex
Castellano, B. M., Thelen, A. M., Moldavski, O., Feltes, M., van der Welle, R. E. N., Mydock-McGrane, L., Jiang, X., van Eijkeren, R. J., Davis, O. B., Louie, S. M., et al. (2017) · Science
PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy
Cited by 562
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Necroptosis: A Specialized Pathway of Programmed Necrosis
Galluzzi, L., & Kroemer, G. (2008) · Cell
Cell death mechanisms and regulationNF-κB Signaling Pathways
Cited by 561
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Connecting Chromosomes, Crisis, and Cancer
Maser, R. S., & DePinho, R. A. (2002) · Science
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 561
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Exome sequencing and characterization of 49,960 individuals in the UK Biobank
Van Hout, C. V., Tachmazidou, I., Backman, J. D., Hoffman, J. D., Liu, D., Pandey, A. K., Gonzaga-Jauregui, C., Khalid, S., Ye, B., Banerjee, N., et al. (2020) · Nature
Genomics and Rare DiseasesGenetic Associations and Epidemiology
Cited by 561
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Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
Ivan, M., Haberberger, T., Gervasi, D. C., Michelson, K. S., Günzler, V., Kondo, K., Yang, H., Sorokina, I., Conaway, R. C., Conaway, J. W., et al. (2002) · Proceedings of the National Academy of Sciences
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 561
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Diabetes Mellitus and the Risk of Cancer: Results From a Large-Scale Population-Based Cohort Study in Japan
Inoue, M. (2006) · Archives of Internal Medicine
Metabolism, Diabetes, and CancerCancer Risks and Factors
Cited by 561
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Endometrial stem/progenitor cells: the first 10 years
Gargett, C. E., Schwab, K. E., & Deane, J. A. (2015) · Human Reproduction Update
Mesenchymal stem cell researchCancer Cells and Metastasis
Cited by 561
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Nongenomic steroid action: controversies, questions, and answers
LÖSEL, R. M., FALKENSTEIN, E., FEURING, M., SCHULTZ, A., TILLMANN, H.-C., ROSSOL-HASEROTH, K., & WEHLING, M. (2003) · Physiological Reviews
Estrogen and related hormone effectsReceptor Mechanisms and Signaling
Cited by 561
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Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites
Guo, H., Chou, W.-C., Lai, Y., Liang, K., Tam, J. W., Brickey, W. J., Chen, L., Montgomery, N. D., Li, X., Bohannon, L. M., et al. (2020) · Science
Gut microbiota and healthEffects of Radiation Exposure
Cited by 561
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An integrated expression atlas of miRNAs and their promoters in human and mouse
The FANTOM Consortium, de Rie, D., Abugessaisa, I., Alam, T., Arner, E., Arner, P., Ashoor, H., Åström, G., Babina, M., Bertin, N., et al. (2017) · Nature Biotechnology
MicroRNA in disease regulationGenomics and Chromatin Dynamics
Cited by 561
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Self-organization and symmetry breaking in intestinal organoid development
Serra, D., Mayr, U., Boni, A., Lukonin, I., Rempfler, M., Challet Meylan, L., Stadler, M. B., Strnad, P., Papasaikas, P., Vischi, D., et al. (2019) · Nature
Hippo pathway signaling and YAP/TAZDevelopmental Biology and Gene Regulation
Cited by 561
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MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression
Ivanovska, I., Ball, A. S., Diaz, R. L., Magnus, J. F., Kibukawa, M., Schelter, J. M., Kobayashi, S. V., Lim, L., Burchard, J., Jackson, A. L., et al. (2008) · Molecular and Cellular Biology
MicroRNA in disease regulationCancer-related Molecular Pathways
Cited by 561
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Transport of Extracellular Vesicles across the Blood-Brain Barrier: Brain Pharmacokinetics and Effects of Inflammation
Banks, W. A., Sharma, P., Bullock, K. M., Hansen, K. M., Ludwig, N., & Whiteside, T. L. (2020) · International Journal of Molecular Sciences
Extracellular vesicles in diseaseBarrier Structure and Function Studies
Cited by 561
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Parental influence on human germline de novo mutations in 1,548 trios from Iceland
Jónsson, H., Sulem, P., Kehr, B., Kristmundsdottir, S., Zink, F., Hjartarson, E., Hardarson, M. T., Hjorleifsson, K. E., Eggertsson, H. P., Gudjonsson, S. A., et al. (2017) · Nature
Genomics and Rare DiseasesGenomic variations and chromosomal abnormalities
Cited by 561
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Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis
Bergeron, R., Ren, J. M., Cadman, K. S., Moore, I. K., Perret, P., Pypaert, M., Young, L. H., Semenkovich, C. F., & Shulman, G. I. (2001) · American Journal of Physiology-Endocrinology and Metabolism
Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism
Cited by 561
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Extracellular ATP or ADP Induce Chemotaxis of Cultured Microglia through Gi/o-Coupled P2Y Receptors
Honda, S., Sasaki, Y., Ohsawa, K., Imai, Y., Nakamura, Y., Inoue, K., & Kohsaka, S. (2001) · The Journal of Neuroscience
Adenosine and Purinergic SignalingNeuroinflammation and Neurodegeneration Mechanisms
Cited by 561
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Parallel SUMOylation-Dependent Pathways Mediate Gene- and Signal-Specific Transrepression by LXRs and PPARγ
Ghisletti, S., Huang, W., Ogawa, S., Pascual, G., Lin, M.-E., Willson, T. M., Rosenfeld, M. G., & Glass, C. K. (2007) · Molecular Cell
Peroxisome Proliferator-Activated ReceptorsNuclear Receptors and Signaling
Cited by 561
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Single-stranded DNA library preparation for the sequencing of ancient or damaged DNA
Gansauge, M.-T., & Meyer, M. (2013) · Nature Protocols
Genomics and Phylogenetic StudiesForensic and Genetic Research
Cited by 561
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Abnormal Development of Dendritic Spines in FMR1 Knock-Out Mice
Nimchinsky, E. A., Oberlander, A. M., & Svoboda, K. (2001) · The Journal of Neuroscience
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 560
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Etiology of Type 1 Diabetes
Todd, J. A. (2010) · Immunity
Diabetes and associated disordersGenetic Associations and Epidemiology
Cited by 560
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How Ligands Illuminate GPCR Molecular Pharmacology
Wacker, D., Stevens, R. C., & Roth, B. L. (2017) · Cell
Receptor Mechanisms and SignalingNeuroscience and Neuropharmacology Research
Cited by 560
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Clathrin
Kirchhausen, T. (2000) · Annual Review of Biochemistry
Cellular transport and secretionReceptor Mechanisms and Signaling
Cited by 560
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