Most cited biochemistry, genetics and molecular biology papers
- Verified
Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3
Pioletti, M., Schlünzen, F., Harms, J., Zarivach, R., Glühmann, M., Avila, H., Bashan, A., Bartels, H., Auerbach, T., Jacobi, C., et al. (2001) · The EMBO Journal
RNA and protein synthesis mechanismsRNA modifications and cancer
Cited by 527
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Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis
WIEMANN, S. U., SATYANARAYANA, A., TSAHURIDU, M., TILLMANN, H. L., ZENDER, L., KLEMPNAUER, J., FLEMMING, P., FRANCO, S., BLASCO, M. A., MANNS, M. P., et al. (2002) · The FASEB Journal
Telomeres, Telomerase, and SenescenceLiver physiology and pathology
Cited by 527
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Analysis of neocortex in three males with the Fragile X syndrome
Hinton, V. J., Brown, W. T., Wisniewski, K., & Rudelli, R. D. (1991) · American Journal of Medical Genetics
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 527
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Clinical Acquired Resistance to KRASG12C Inhibition through a Novel KRAS Switch-II Pocket Mutation and Polyclonal Alterations Converging on RAS–MAPK Reactivation
Tanaka, N., Lin, J. J., Li, C., Ryan, M. B., Zhang, J., Kiedrowski, L. A., Michel, A. G., Syed, M. U., Fella, K. A., Sakhi, M., et al. (2021) · Cancer Discovery
Protein Kinase Regulation and GTPase SignalingLung Cancer Treatments and Mutations
Cited by 527
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Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals
Buck, J., Sinclair, M. L., Schapal, L., Cann, M. J., & Levin, L. R. (1999) · Proceedings of the National Academy of Sciences
Receptor Mechanisms and SignalingPhosphodiesterase function and regulation
Cited by 527
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Itraconazole, a Commonly Used Antifungal that Inhibits Hedgehog Pathway Activity and Cancer Growth
Kim, J., Tang, J. Y., Gong, R., Kim, J., Lee, J. J., Clemons, K. V., Chong, C. R., Chang, K. S., Fereshteh, M., Gardner, D., et al. (2010) · Cancer Cell
Hedgehog Signaling Pathway StudiesHippo pathway signaling and YAP/TAZ
Cited by 527
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Alveolar Cell Senescence in Patients with Pulmonary Emphysema
Tsuji, T., Aoshiba, K., & Nagai, A. (2006) · American Journal of Respiratory and Critical Care Medicine
Telomeres, Telomerase, and SenescenceChronic Obstructive Pulmonary Disease (COPD) Research
Cited by 527
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Alternative splicing in disease and therapy
Garcia-Blanco, M. A., Baraniak, A. P., & Lasda, E. L. (2004) · Nature Biotechnology
RNA Research and SplicingRNA regulation and disease
Cited by 527
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The role of the microbiome in human health and disease: An introduction for clinicians
Young, V. B. (2017) · BMJ
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 527
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Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling
Burgoyne, R. D. (2007) · Nature Reviews Neuroscience
S100 Proteins and AnnexinsIon channel regulation and function
Cited by 527
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Mitochondrial Oxidative Stress Mediates Angiotensin II–Induced Cardiac Hypertrophy and Gαq Overexpression–Induced Heart Failure
Dai, D.-F., Johnson, S. C., Villarin, J. J., Chin, M. T., Nieves-Cintrón, M., Chen, T., Marcinek, D. J., Dorn, G. W., Kang, Y. J., Prolla, T. A., et al. (2011) · Circulation Research
Mitochondrial Function and PathologyCardiac Fibrosis and Remodeling
Cited by 527
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Levinthal's paradox.
Zwanzig, R., Szabo, A., & Bagchi, B. (1992) · Proceedings of the National Academy of Sciences
Protein Structure and DynamicsRNA and protein synthesis mechanisms
Cited by 527
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Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
Rudolph, K. L., Millard, M., Bosenberg, M. W., & DePinho, R. A. (2001) · Nature Genetics
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 527
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Biosynthetic controls that determine the branching and microheterogeneity of protein-bound oligosaccharides
Schachter, H. (1986) · Biochemistry and Cell Biology
Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis
Cited by 526
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N-Acetylcysteine (NAC): Impacts on Human Health
Tenório, M. C. D. S., Graciliano, N. G., Moura, F. A., Oliveira, A. C. M. D., & Goulart, M. O. F. (2021) · Antioxidants
Sulfur Compounds in BiologyDrug-Induced Hepatotoxicity and Protection
Cited by 526
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Telomere Length Homeostasis Is Achieved via a Switch between Telomerase- Extendible and -Nonextendible States
Teixeira, M. T., Arneric, M., Sperisen, P., & Lingner, J. (2004) · Cell
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 526
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Single-Cell Gene Expression Profiling
Levsky, J. M., Shenoy, S. M., Pezo, R. C., & Singer, R. H. (2002) · Science
Single-cell and spatial transcriptomicsAdvanced Fluorescence Microscopy Techniques
Cited by 526
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Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide
Lu, J., Chew, E.-H., & Holmgren, A. (2007) · Proceedings of the National Academy of Sciences
Redox biology and oxidative stressSelenium in Biological Systems
Cited by 526
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An unbiased genome-wide analysis of zinc-finger nuclease specificity
Gabriel, R., Lombardo, A., Arens, A., Miller, J. C., Genovese, P., Kaeppel, C., Nowrouzi, A., Bartholomae, C. C., Wang, J., Friedman, G., et al. (2011) · Nature Biotechnology
CRISPR and Genetic EngineeringVirus-based gene therapy research
Cited by 526
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Activation of Necroptosis in Multiple Sclerosis
Ofengeim, D., Ito, Y., Najafov, A., Zhang, Y., Shan, B., DeWitt, J. P., Ye, J., Zhang, X., Chang, A., Vakifahmetoglu-Norberg, H., et al. (2015) · Cell Reports
Cell death mechanisms and regulationMultiple Sclerosis Research Studies
Cited by 526
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Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells
Radhakrishnan, S. K., Lee, C. S., Young, P., Beskow, A., Chan, J. Y., & Deshaies, R. J. (2010) · Molecular Cell
Ubiquitin and proteasome pathwaysGenomics, phytochemicals, and oxidative stress
Cited by 526
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A Critical Requirement for Notch Signaling in Maintenance of the Quiescent Skeletal Muscle Stem Cell State
Mourikis, P., Sambasivan, R., Castel, D., Rocheteau, P., Bizzarro, V., & Tajbakhsh, S. (2012) · Stem Cells
Muscle Physiology and DisordersDevelopmental Biology and Gene Regulation
Cited by 526
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Population structure, differential bias and genomic control in a large-scale, case-control association study
Clayton, D. G., Walker, N. M., Smyth, D. J., Pask, R., Cooper, J. D., Maier, L. M., Smink, L. J., Lam, A. C., Ovington, N. R., Stevens, H. E., et al. (2005) · Nature Genetics
Genetic Associations and EpidemiologyForensic and Genetic Research
Cited by 526
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Modeling human cortical development in vitro using induced pluripotent stem cells
Mariani, J., Simonini, M. V., Palejev, D., Tomasini, L., Coppola, G., Szekely, A. M., Horvath, T. L., & Vaccarino, F. M. (2012) · Proceedings of the National Academy of Sciences
Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms
Cited by 526
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