Most cited biochemistry, genetics and molecular biology papers
- Verified
ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development
Nakagawa, H., Umemura, A., Taniguchi, K., Font-Burgada, J., Dhar, D., Ogata, H., Zhong, Z., Valasek, M. A., Seki, E., Hidalgo, J., et al. (2014) · Cancer Cell
Endoplasmic Reticulum Stress and DiseaseCancer, Lipids, and Metabolism
Cited by 525
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The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCFβ-TrCP E3 Ligase
Liu, C.-Y., Zha, Z.-Y., Zhou, X., Zhang, H., Huang, W., Zhao, D., Li, T., Chan, S. W., Lim, C. J., Hong, W., et al. (2010) · Journal of Biological Chemistry
Hippo pathway signaling and YAP/TAZUbiquitin and proteasome pathways
Cited by 525
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Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection
Gazal, S., Finucane, H. K., Furlotte, N. A., Loh, P.-R., Palamara, P. F., Liu, X., Schoech, A., Bulik-Sullivan, B., Neale, B. M., Gusev, A., et al. (2017) · Nature Genetics
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 525
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Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant ?-lipoic acid: A 3-week multicentre randomized controlled trial (ALADIN Study)
Ziegler, D., Hanefeld, M., Ruhnau, K. J., Mei\ner, H. P., Lobisch, M., Sch�tte, K., Gries, F. A., & The ALADIN Study Group (1995) · Diabetologia
Biochemical Acid Research StudiesPain Mechanisms and Treatments
Cited by 525
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Hypertension-Linked Pathophysiological Alterations in the Gut
Santisteban, M. M., Qi, Y., Zubcevic, J., Kim, S., Yang, T., Shenoy, V., Cole-Jeffrey, C. T., Lobaton, G. O., Stewart, D. C., Rubiano, A., et al. (2017) · Circulation Research
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 525
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Mitochondrial Trafficking in Neurons
Schwarz, T. L. (2013) · Cold Spring Harbor Perspectives in Biology
Mitochondrial Function and PathologyMicrotubule and mitosis dynamics
Cited by 525
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Protein Tyrosine Nitration: Biochemical Mechanisms and Structural Basis of Functional Effects
Radi, R. (2013) · Accounts of Chemical Research
Redox biology and oxidative stressNitric Oxide and Endothelin Effects
Cited by 525
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Shedding light on the grey zone of speciation along a continuum of genomic divergence
Roux, C., Fraïsse, C., Romiguier, J., Anciaux, Y., Galtier, N., & Bierne, N. (2016) · PLOS Biology
Genetic diversity and population structureEvolution and Paleontology Studies
Cited by 525
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Quantitative Phosphoproteomics Reveal mTORC1 Activates de Novo Pyrimidine Synthesis
Robitaille, A. M., Christen, S., Shimobayashi, M., Cornu, M., Fava, L. L., Moes, S., Prescianotto-Baschong, C., Sauer, U., Jenoe, P., & Hall, M. N. (2013) · Science
PI3K/AKT/mTOR signaling in cancerBiochemical and Molecular Research
Cited by 525
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Metabolic landscape of the tumor microenvironment at single cell resolution
Xiao, Z., Dai, Z., & Locasale, J. W. (2019) · Nature Communications
Cancer, Hypoxia, and MetabolismSingle-cell and spatial transcriptomics
Cited by 524
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Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease
Srikanth, V., Maczurek, A., Phan, T., Steele, M., Westcott, B., Juskiw, D., & Münch, G. (2011) · Neurobiology of Aging
Advanced Glycation End Products researchAlzheimer's disease research and treatments
Cited by 524
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Epigenetic balance of gene expression by Polycomb and COMPASS families
Piunti, A., & Shilatifard, A. (2016) · Science
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 524
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Cloning and characterization of a vasopressin V2 receptor and possible link to nephrogenic diabetes insipidus
Lolait, S. J., O'Carroll, A.-M., McBride, O. W., Konig, M., Morel, A., & Brownstein, M. J. (1992) · Nature
Ion Transport and Channel RegulationElectrolyte and hormonal disorders
Cited by 524
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Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells
Eling, N., Reuter, L., Hazin, J., Hamacher-Brady, A., & Brady, N. R. (2015) · Oncoscience
Ferroptosis and cancer prognosisCell death mechanisms and regulation
Cited by 524
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Bulk-solvent and hydration-shell fluctuations, similar to α- and β-fluctuations in glasses, control protein motions and functions
Fenimore, P. W., Frauenfelder, H., McMahon, B. H., & Young, R. D. (2004) · Proceedings of the National Academy of Sciences
Protein Structure and DynamicsMaterial Dynamics and Properties
Cited by 524
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Metastatic and triple-negative breast cancer: challenges and treatment options
Al-Mahmood, S., Sapiezynski, J., Garbuzenko, O. B., & Minko, T. (2018) · Drug Delivery and Translational Research
Breast Cancer Treatment StudiesHER2/EGFR in Cancer Research
Cited by 524
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Single-cell multiomics: technologies and data analysis methods
Lee, J., Hyeon, D. Y., & Hwang, D. (2020) · Experimental & Molecular Medicine
Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics
Cited by 524
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RNAi in Budding Yeast
Drinnenberg, I. A., Weinberg, D. E., Xie, K. T., Mower, J. P., Wolfe, K. H., Fink, G. R., & Bartel, D. P. (2009) · Science
RNA Interference and Gene DeliveryRNA Research and Splicing
Cited by 524
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The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape
Weinberg, D. N., Papillon-Cavanagh, S., Chen, H., Yue, Y., Chen, X., Rajagopalan, K. N., Horth, C., McGuire, J. T., Xu, X., Nikbakht, H., et al. (2019) · Nature
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 524
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A Protein-Counting Mechanism for Telomere Length Regulation in Yeast
Marcand, S., Gilson, E., & Shore, D. (1997) · Science
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 524
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Steroid sulfatase: molecular biology, regulation, and inhibition
Reed, M. J., Purohit, A., Woo, L. W. L., Newman, S. P., & Potter, B. V. L. (2005) · Endocrine Reviews
Estrogen and related hormone effectsSteroid Chemistry and Biochemistry
Cited by 524
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The role of cellular senescence in ageing and endocrine disease
Khosla, S., Farr, J. N., Tchkonia, T., & Kirkland, J. L. (2020) · Nature Reviews Endocrinology
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 523
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Neuroprotective effects of estrogens: potential mechanisms of action
Green, P. S., & Simpkins, J. W. (2000) · International Journal of Developmental Neuroscience
Estrogen and related hormone effectsMenopause: Health Impacts and Treatments
Cited by 523
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Autophagy: Basic Principles and Relevance to Disease
Kundu, M., & Thompson, C. B. (2008) · Annual Review of Pathology: Mechanisms of Disease
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 523
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