Most cited biochemistry, genetics and molecular biology papers
- Verified
Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells
Durai, S. (2005) · Nucleic Acids Research
CRISPR and Genetic EngineeringRNA Interference and Gene Delivery
Cited by 522
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Analysis of Transduction Efficiency, Tropism and Axonal Transport of AAV Serotypes 1, 2, 5, 6, 8 and 9 in the Mouse Brain
Aschauer, D. F., Kreuz, S., & Rumpel, S. (2013) · PLoS ONE
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 522
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Metabolic costs of terpenoid accumulation in higher plants
Gershenzon, J. (1994) · Journal of Chemical Ecology
Plant biochemistry and biosynthesisInsect-Plant Interactions and Control
Cited by 522
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Permanent Alteration of PCSK9 With In Vivo CRISPR-Cas9 Genome Editing
Ding, Q., Strong, A., Patel, K. M., Ng, S.-L., Gosis, B. S., Regan, S. N., Cowan, C. A., Rader, D. J., & Musunuru, K. (2014) · Circulation Research
CRISPR and Genetic EngineeringLipoproteins and Cardiovascular Health
Cited by 522
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Aptamer-based targeted therapy
Zhu, G., & Chen, X. (2018) · Advanced Drug Delivery Reviews
Advanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery
Cited by 522
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The cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes
Blazek, D., Kohoutek, J., Bartholomeeusen, K., Johansen, E., Hulinkova, P., Luo, Z., Cimermancic, P., Ule, J., & Peterlin, B. M. (2011) · Genes & Development
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 522
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Oxytosis: a novel form of programmed cell death
Shirlee Tan, B. S. P., David Schubert, B. S. P., & Pamela Maher, B. S. P. (2001) · Current Topics in Medicinal Chemistry
Cell death mechanisms and regulationRedox biology and oxidative stress
Cited by 522
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Mechanism of telomere shortening by oxidative stress
KAWANISHI, S., & OIKAWA, S. (2004) · Annals of the New York Academy of Sciences
Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms
Cited by 522
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New insights into the role of mitochondria in aging: mitochondrial dynamics and more
Seo, A. Y., Joseph, A.-M., Dutta, D., Hwang, J. C. Y., Aris, J. P., & Leeuwenburgh, C. (2010) · Journal of Cell Science
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 522
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Adenovirus oncoproteins inactivate the Mre11–Rad50–NBS1 DNA repair complex
Stracker, T. H., Carson, C. T., & Weitzman, M. D. (2002) · Nature
DNA Repair MechanismsVirus-based gene therapy research
Cited by 522
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Ubiquitination: RING for destruction?
Freemont, P. S. (2000) · Current Biology
Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors
Cited by 522
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RAG1 Core and V(D)J Recombination Signal Sequences Were Derived from Transib Transposons
Kapitonov, V. V., & Jurka, J. (2005) · PLoS Biology
Chromosomal and Genetic VariationsDNA Repair Mechanisms
Cited by 521
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Topology of mammalian developmental enhancers and their regulatory landscapes
de Laat, W., & Duboule, D. (2013) · Nature
Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation
Cited by 521
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Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data
Pique-Regi, R., Degner, J. F., Pai, A. A., Gaffney, D. J., Gilad, Y., & Pritchard, J. K. (2011) · Genome Research
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 521
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The Occurrence of iε-N-Methyl Lysine in Histones
Murray, K. (1964) · Biochemistry
Genomics and Chromatin DynamicsCancer-related gene regulation
Cited by 521
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Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors
Müller, M. J. I., Klumpp, S., & Lipowsky, R. (2008) · Proceedings of the National Academy of Sciences
Microtubule and mitosis dynamicsstochastic dynamics and bifurcation
Cited by 521
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Molecular taxonomy of major neuronal classes in the adult mouse forebrain
Sugino, K., Hempel, C. M., Miller, M. N., Hattox, A. M., Shapiro, P., Wu, C., Huang, Z. J., & Nelson, S. B. (2006) · Nature Neuroscience
Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research
Cited by 521
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Chapter Two Intraflagellar Transport (IFT)
Pedersen, L. B., & Rosenbaum, J. L. (2008) · Current Topics in Developmental Biology
Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances
Cited by 521
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Exercise and the gut microbiome: A review of the evidence, potential mechanisms, and implications for human health
Mailing, L. J., Allen, J. M., Buford, T. W., Fields, C. J., & Woods, J. A. (2019) · Exercise and Sport Sciences Reviews
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 521
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Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination
Tang, J., Cho, N. W., Cui, G., Manion, E. M., Shanbhag, N. M., Botuyan, M. V., Mer, G., & Greenberg, R. A. (2013) · Nature Structural & Molecular Biology
DNA Repair MechanismsPARP inhibition in cancer therapy
Cited by 521
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Sterol Regulatory Element-binding Proteins (SREBPs): Key Regulators of Nutritional Homeostasis and Insulin Action
Osborne, T. F. (2000) · Journal of Biological Chemistry
Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism
Cited by 521
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Histone deacetylase 6 structure and molecular basis of catalysis and inhibition
Hai, Y., & Christianson, D. W. (2016) · Nature Chemical Biology
Histone Deacetylase Inhibitors ResearchEnzyme Structure and Function
Cited by 521
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Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis
Plechanovová, A., Jaffray, E. G., Tatham, M. H., Naismith, J. H., & Hay, R. T. (2012) · Nature
Ubiquitin and proteasome pathwaysEnzyme Structure and Function
Cited by 521
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Thioredoxin Reductase Is Irreversibly Modified by Curcumin
Fang, J., Lu, J., & Holmgren, A. (2005) · Journal of Biological Chemistry
Redox biology and oxidative stressCurcumin's Biomedical Applications
Cited by 521
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