Most cited biochemistry, genetics and molecular biology papers
- Verified
NF‐κB inhibits TNF‐induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death
Sakon, S., Xue, X., Takekawa, M., Sasazuki, T., Okazaki, T., Kojima, Y., Piao, J., Yagita, H., Okumura, K., Doi, T., et al. (2003) · The EMBO Journal
NF-κB Signaling PathwaysCell death mechanisms and regulation
Cited by 497
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Genome-wide structure and organization of eukaryotic pre-initiation complexes
Rhee, H. S., & Pugh, B. F. (2012) · Nature
Genomics and Chromatin DynamicsNuclear Structure and Function
Cited by 496
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Vertical Pathway Inhibition Overcomes Adaptive Feedback Resistance to KRASG12C Inhibition
Ryan, M. B., Fece de la Cruz, F., Phat, S., Myers, D. T., Wong, E., Shahzade, H. A., Hong, C. B., & Corcoran, R. B. (2020) · Clinical Cancer Research
Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways
Cited by 496
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Sialic acids sweeten a tumor's life
Büll, C., Stoel, M. A., den Brok, M. H., & Adema, G. J. (2014) · Cancer Research
Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis
Cited by 496
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An Update of the Oxidation-Inflammation Theory of Aging: The Involvement of the Immune System in Oxi-Inflamm-Aging
Fuente, M., & Miquel, J. (2009) · Current Pharmaceutical Design
Genetics, Aging, and Longevity in Model OrganismsExercise and Physiological Responses
Cited by 496
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Turning 21: Induction of miR-21 as a Key Switch in the Inflammatory Response
Sheedy, F. J. (2015) · Frontiers in Immunology
MicroRNA in disease regulationImmune Response and Inflammation
Cited by 496
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Autophagy in kidney homeostasis and disease
Tang, C., Livingston, M. J., Liu, Z., & Dong, Z. (2020) · Nature Reviews Nephrology
Autophagy in Disease and TherapyRenal Diseases and Glomerulopathies
Cited by 496
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Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis
Ruhland, M. K., Loza, A. J., Capietto, A.-H., Luo, X., Knolhoff, B. L., Flanagan, K. C., Belt, B. A., Alspach, E., Leahy, K., Luo, J., et al. (2016) · Nature Communications
Telomeres, Telomerase, and SenescenceImmune cells in cancer
Cited by 496
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A role for glia in the progression of Rett’s syndrome
Lioy, D. T., Garg, S. K., Monaghan, C. E., Raber, J., Foust, K. D., Kaspar, B. K., Hirrlinger, P. G., Kirchhoff, F., Bissonnette, J. M., Ballas, N., et al. (2011) · Nature
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 496
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TORC1 inhibition enhances immune function and reduces infections in the elderly
Mannick, J. B., Morris, M., Hockey, H.-U. P., Roma, G., Beibel, M., Kulmatycki, K., Watkins, M., Shavlakadze, T., Zhou, W., Quinn, D., et al. (2018) · Science Translational Medicine
PI3K/AKT/mTOR signaling in cancerGenetics, Aging, and Longevity in Model Organisms
Cited by 496
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International Union of Pharmacology. LXIII. Retinoid X receptors
Germain, P., Chambon, P., Eichele, G., Evans, R. M., Lazar, M. A., Leid, M., De Lera, A. R., Lotan, R., Mangelsdorf, D. J., & Gronemeyer, H. (2006) · Pharmacological Reviews
Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors
Cited by 496
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Microbial Translocation Across the GI Tract
Brenchley, J. M., & Douek, D. C. (2012) · Annual Review of Immunology
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 496
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Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1−/− mice.
Scortegagna, M., Ding, K., Oktay, Y., Gaur, A., Thurmond, F., Yan, L.-J., Marck, B. T., Matsumoto, A. M., Shelton, J. M., Richardson, J. A., et al. (2003) · Nature Genetics
Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress
Cited by 496
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Melanoma: from mutations to medicine
Tsao, H., Chin, L., Garraway, L. A., & Fisher, D. E. (2012) · Genes & Development
Melanoma and MAPK PathwaysCutaneous Melanoma Detection and Management
Cited by 496
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BRCA1 required for transcription-coupled repair of oxidative DNA damage
Gowen, L. C., Avrutskaya, A. V., Latour, A. M., Koller, B. H., & Leadon, S. A. (1998) · Science
DNA Repair MechanismsBRCA gene mutations in cancer
Cited by 496
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Targeting the gut and tumor microbiota in cancer
Park, E. M., Chelvanambi, M., Bhutiani, N., Kroemer, G., Zitvogel, L., & Wargo, J. A. (2022) · Nature Medicine
Gut microbiota and healthCancer Immunotherapy and Biomarkers
Cited by 496
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Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease
Pistollato, F., Sumalla Cano, S., Elio, I., Masias Vergara, M., Giampieri, F., & Battino, M. (2016) · Nutrition Reviews
Gut microbiota and healthAlzheimer's disease research and treatments
Cited by 496
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Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women
Wang, Z., Bergeron, N., Levison, B. S., Li, X. S., Chiu, S., Jia, X., Koeth, R. A., Li, L., Wu, Y., Tang, W. H. W., et al. (2019) · European Heart Journal
Gut microbiota and healthNutritional Studies and Diet
Cited by 496
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Metalloproteinase Expression in Monocytes and Macrophages and its Relationship to Atherosclerotic Plaque Instability
Newby, A. C. (2008) · Arteriosclerosis, Thrombosis, and Vascular Biology
Protease and Inhibitor MechanismsAtherosclerosis and Cardiovascular Diseases
Cited by 496
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A long-acting FGF21 molecule, PF-05231023, decreases body weight and improves lipid profile in non-human primates and type 2 diabetic subjects
Talukdar, S., Zhou, Y., Li, D., Rossulek, M., Dong, J., Somayaji, V., Weng, Y., Clark, R., Lanba, A., Owen, B. M., et al. (2016) · Cell Metabolism
Fibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic Diseases
Cited by 496
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Chapter 12: Human Microbiome Analysis
Morgan, X. C., & Huttenhower, C. (2012) · PLoS Computational Biology
Gut microbiota and healthGenomics and Phylogenetic Studies
Cited by 496
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Inhibition of Mitochondrial Respiration
Pelicano, H., Feng, L., Zhou, Y., Carew, J. S., Hileman, E. O., Plunkett, W., Keating, M. J., & Huang, P. (2003) · Journal of Biological Chemistry
Mitochondrial Function and PathologyCell death mechanisms and regulation
Cited by 495
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The impact of structural variation on human gene expression
GTEx Consortium, Chiang, C., Scott, A. J., Davis, J. R., Tsang, E. K., Li, X., Kim, Y., Hadzic, T., Damani, F. N., Ganel, L., et al. (2017) · Nature Genetics
Genomic variations and chromosomal abnormalitiesGenetic Associations and Epidemiology
Cited by 495
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Phage-guided modulation of the gut microbiota of mouse models of colorectal cancer augments their responses to chemotherapy
Zheng, D.-W., Dong, X., Pan, P., Chen, K.-W., Fan, J.-X., Cheng, S.-X., & Zhang, X.-Z. (2019) · Nature Biomedical Engineering
Bacterial Cancer TherapyNanoparticle-Based Drug Delivery
Cited by 495
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