Most cited biochemistry, genetics and molecular biology papers
- Verified
GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex
Tisdale, E. J., Bourne, J. R., Khosravi-Far, R., Der, C. J., & Balch, W. E. (1992) · The Journal of cell biology
Cellular transport and secretionProtein Kinase Regulation and GTPase Signaling
Cited by 500
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MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers
Seike, M., Goto, A., Okano, T., Bowman, E. D., Schetter, A. J., Horikawa, I., Mathe, E. A., Jen, J., Yang, P., Sugimura, H., et al. (2009) · Proceedings of the National Academy of Sciences
MicroRNA in disease regulationLung Cancer Treatments and Mutations
Cited by 500
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Transcriptional regulation by Ferric Uptake Regulator (Fur) in pathogenic bacteria
Troxell, B., & Hassan, H. M. (2013) · Frontiers in Cellular and Infection Microbiology
Bacterial Genetics and BiotechnologyEscherichia coli research studies
Cited by 500
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RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues
Yizhak, K., Aguet, F., Kim, J., Hess, J. M., Kübler, K., Grimsby, J., Frazer, R., Zhang, H., Haradhvala, N. J., Rosebrock, D., et al. (2019) · Science
Cancer Genomics and DiagnosticsSingle-cell and spatial transcriptomics
Cited by 500
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Regulation of autophagy by cytosolic acetyl-coenzyme A
Mariño, G., Pietrocola, F., Eisenberg, T., Kong, Y., Malik, S. A., Andryushkova, A., Schroeder, S., Pendl, T., Harger, A., Niso-Santano, M., et al. (2014) · Molecular Cell
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 500
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Dual role of calmodulin in autophosphorylation of multifunctional cam kinase may underlie decoding of calcium signals
Hanson, P. I., Meyer, T., Stryer, L., & Schulman, H. (1994) · Neuron
Protein Kinase Regulation and GTPase SignalingIon channel regulation and function
Cited by 500
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A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy
Ronan, B., Flamand, O., Vescovi, L., Dureuil, C., Durand, L., Fassy, F., Bachelot, M.-F., Lamberton, A., Mathieu, M., Bertrand, T., et al. (2014) · Nature Chemical Biology
Autophagy in Disease and TherapyCellular transport and secretion
Cited by 500
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Structure and control of the actin regulatory WAVE complex
Chen, Z., Borek, D., Padrick, S. B., Gomez, T. S., Metlagel, Z., Ismail, A. M., Umetani, J., Billadeau, D. D., Otwinowski, Z., & Rosen, M. K. (2010) · Nature
Cellular Mechanics and InteractionsProtein Kinase Regulation and GTPase Signaling
Cited by 500
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Absolute quantification of matrix metabolites reveals the dynamics of mitochondrial metabolism
Chen, W. W., Freinkman, E., Wang, T., Birsoy, K., & Sabatini, D. M. (2016) · Cell
Mitochondrial Function and PathologyMetabolomics and Mass Spectrometry Studies
Cited by 500
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Regulatory network of miRNA on its target: coordination between transcriptional and post-transcriptional regulation of gene expression
Pu, M., Chen, J., Tao, Z., Miao, L., Qi, X., Wang, Y., & Ren, J. (2019) · Cellular and Molecular Life Sciences
MicroRNA in disease regulationPlant Molecular Biology Research
Cited by 500
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Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer
Wang, Y., Xu, X., Maglic, D., Dill, M. T., Mojumdar, K., Ng, P. K.-S., Jeong, K. J., Tsang, Y. H., Moreno, D., Bhavana, V. H., et al. (2018) · Cell Reports
Hippo pathway signaling and YAP/TAZCancer-related molecular mechanisms research
Cited by 500
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PKC-θ knockout mice are protected from fat-induced insulin resistance
Kim, J. K., Fillmore, J. J., Sunshine, M. J., Albrecht, B., Higashimori, T., Kim, D.-W., Liu, Z.-X., Soos, T. J., Cline, G. W., O’Brien, W. R., et al. (2004) · Journal of Clinical Investigation
Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins
Cited by 500
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Epigenetic contribution to stress adaptation in plants
Mirouze, M., & Paszkowski, J. (2011) · Current Opinion in Plant Biology
Epigenetics and DNA MethylationPlant Molecular Biology Research
Cited by 500
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Cryptic genetic variation: evolution's hidden substrate
Paaby, A. B., & Rockman, M. V. (2014) · Nature Reviews Genetics
Evolution and Genetic DynamicsGenetic diversity and population structure
Cited by 500
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Commensal bacteria make GPCR ligands that mimic human signalling molecules
Cohen, L. J., Esterhazy, D., Kim, S.-H., Lemetre, C., Aguilar, R. R., Gordon, E. A., Pickard, A. J., Cross, J. R., Emiliano, A. B., Han, S. M., et al. (2017) · Nature
Gut microbiota and healthMicrobial Natural Products and Biosynthesis
Cited by 500
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Residual insulin production and pancreatic β-cell turnover after 50 years of diabetes: Joslin Medalist Study
Keenan, H. A., Sun, J. K., Levine, J., Doria, A., Aiello, L. P., Eisenbarth, G., Bonner-Weir, S., & King, G. L. (2010) · Diabetes
Diabetes and associated disordersPancreatic function and diabetes
Cited by 500
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Levels of hypoxia‐inducible factor‐1α independently predict prognosis in patients with lymph node negative breast carcinoma
Bos, R., van der Groep, P., Greijer, A. E., Shvarts, A., Meijer, S., Pinedo, H. M., Semenza, G. L., van Diest, P. J., & van der Wall, E. (2003) · Cancer
Cancer, Hypoxia, and MetabolismBreast Cancer Treatment Studies
Cited by 500
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Mechanism of open complex and dual incision formation by human nucleotide excision repair factors
Evans, E., Moggs, J. G., Hwang, J. R., Egly, J., & Wood, R. D. (1997) · The EMBO Journal
DNA Repair MechanismsDNA and Nucleic Acid Chemistry
Cited by 500
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Nonlinear dynamics of multi-omics profiles during human aging
Shen, X., Wang, C., Zhou, X., Zhou, W., Hornburg, D., Wu, S., & Snyder, M. P. (2024) · Nature Aging
Genetics, Aging, and Longevity in Model OrganismsBioinformatics and Genomic Networks
Cited by 500
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Image reconstructions of helical assemblies of the HIV-1 CA protein
Li, S., Hill, C. P., Sundquist, W. I., & Finch, J. T. (2000) · Nature
Advanced Electron Microscopy Techniques and ApplicationsHIV Research and Treatment
Cited by 500
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The aging lung: Physiology, disease, and immunity
Schneider, J. L., Rowe, J. H., Garcia-de-Alba, C., Kim, C. F., Sharpe, A. H., & Haigis, M. C. (2021) · Cell
Genetics, Aging, and Longevity in Model OrganismsInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Cited by 500
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MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8
Bhaumik, D., Scott, G. K., Schokrpur, S., Patil, C. K., Orjalo, A. V., Rodier, F., Lithgow, G. J., & Campisi, J. (2009) · Aging
Telomeres, Telomerase, and SenescenceMicroRNA in disease regulation
Cited by 500
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Heterochromatin: Guardian of the Genome
Janssen, A., Colmenares, S. U., & Karpen, G. H. (2018) · Annual Review of Cell and Developmental Biology
Genomics and Chromatin DynamicsChromosomal and Genetic Variations
Cited by 500
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Cholesterol metabolism in neurons and astrocytes
Pfrieger, F. W., & Ungerer, N. (2011) · Progress in Lipid Research
Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism
Cited by 500
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