Most cited biochemistry, genetics and molecular biology papers
- Verified
Enhancer–core-promoter specificity separates developmental and housekeeping gene regulation
Zabidi, M. A., Arnold, C. D., Schernhuber, K., Pagani, M., Rath, M., Frank, O., & Stark, A. (2015) · Nature
Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation
Cited by 471
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Wnt/β-Catenin Signaling in Liver Development, Homeostasis, and Pathobiology
Russell, J. O., & Monga, S. P. (2018) · Annual Review of Pathology: Mechanisms of Disease
Wnt/β-catenin signaling in development and cancerLiver physiology and pathology
Cited by 471
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Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis
Green, C. R., Wallace, M., Divakaruni, A. S., Phillips, S. A., Murphy, A. N., Ciaraldi, T. P., & Metallo, C. M. (2016) · Nature Chemical Biology
Lipid metabolism and biosynthesisAdipose Tissue and Metabolism
Cited by 471
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Recent acceleration of human adaptive evolution
Hawks, J., Wang, E. T., Cochran, G. M., Harpending, H. C., & Moyzis, R. K. (2007) · Proceedings of the National Academy of Sciences
Forensic and Genetic ResearchEvolution and Genetic Dynamics
Cited by 471
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TGF-β Promotes Heterogeneity and Drug Resistance in Squamous Cell Carcinoma
Oshimori, N., Oristian, D., & Fuchs, E. (2015) · Cell
TGF-β signaling in diseasesCancer Cells and Metastasis
Cited by 471
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Short-chain fatty acids manifest stimulative and protective effects on intestinal barrier function through the inhibition of NLRP3 inflammasome and autophagy
Feng, Y., Wang, Y., Wang, P., Huang, Y., & Wang, F. (2018) · Cellular Physiology and Biochemistry
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 471
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DNA methylation and chromatin – unraveling the tangled web
Robertson, K. D. (2002) · Oncogene
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 471
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Mitochondrial reactive oxygen species production in excitable cells: Modulators of mitochondrial and cell function
Stowe, D. F., & Camara, A. K. S. (2009) · Antioxidants & Redox Signaling
Mitochondrial Function and PathologyRedox biology and oxidative stress
Cited by 471
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Modeling Alzheimer’s disease with iPSC-derived brain cells
Penney, J., Ralvenius, W. T., & Tsai, L.-H. (2020) · Molecular Psychiatry
Pluripotent Stem Cells ResearchAlzheimer's disease research and treatments
Cited by 471
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Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients
Bost, P., Giladi, A., Liu, Y., Bendjelal, Y., Xu, G., David, E., Blecher-Gonen, R., Cohen, M., Medaglia, C., Li, H., et al. (2020) · Cell
Single-cell and spatial transcriptomicsSARS-CoV-2 and COVID-19 Research
Cited by 471
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Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl‐CpG binding protein.
Boyes, J., & Bird, A. (1992) · The EMBO Journal
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 471
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Flow-dependent YAP/TAZ activities regulate endothelial phenotypes and atherosclerosis
Wang, K.-C., Yeh, Y.-T., Nguyen, P., Limqueco, E., Lopez, J., Thorossian, S., Guan, K.-L., Li, Y.-S. J., & Chien, S. (2016) · Proceedings of the National Academy of Sciences
Hippo pathway signaling and YAP/TAZAtherosclerosis and Cardiovascular Diseases
Cited by 471
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Impact of regulatory variation from RNA to protein
Battle, A., Khan, Z., Wang, S. H., Mitrano, A., Ford, M. J., Pritchard, J. K., & Gilad, Y. (2015) · Science
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 471
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Disease states associated with telomerase deficiency appear earlier in mice with short telomeres
Herrera, E., Samper, E., Martín‐Caballero, J., Flores, J. M., Lee, H., & Blasco, M. A. (1999) · The EMBO Journal
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 471
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The cell biology of systemic insulin function
Tokarz, V. L., MacDonald, P. E., & Klip, A. (2018) · Journal of Cell Biology
Metabolism, Diabetes, and CancerPancreatic function and diabetes
Cited by 471
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Disruption of the neurexin 1 gene is associated with schizophrenia
Rujescu, D., Ingason, A., Cichon, S., Pietiläinen, O. P. H., Barnes, M. R., Toulopoulou, T., Picchioni, M., Vassos, E., Ettinger, U., Bramon, E., et al. (2009) · Human Molecular Genetics
Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment
Cited by 471
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Expanding TRAF function: TRAF3 as a tri-faced immune regulator
Häcker, H., Tseng, P.-H., & Karin, M. (2011) · Nature Reviews Immunology
NF-κB Signaling PathwaysImmune Response and Inflammation
Cited by 471
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Feature selection and dimension reduction for single-cell RNA-Seq based on a multinomial model
Townes, F. W., Hicks, S. C., Aryee, M. J., & Irizarry, R. A. (2019) · Genome Biology
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 471
- VerifiedRetracted
RETRACTED ARTICLE: A mechanism for the suppression of homologous recombination in G1 cells
Orthwein, A., Noordermeer, S. M., Wilson, M. D., Landry, S., Enchev, R. I., Sherker, A., Munro, M., Pinder, J., Salsman, J., Dellaire, G., et al. (2015) · Nature
DNA Repair MechanismsBRCA gene mutations in cancer
Cited by 471
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Full crop protection from an insect pest by expression of long double-stranded RNAs in plastids
Zhang, J., Khan, S. A., Hasse, C., Ruf, S., Heckel, D. G., & Bock, R. (2015) · Science
Insect Resistance and GeneticsTransgenic Plants and Applications
Cited by 471
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Chronic inflammation and the hallmarks of aging
Baechle, J. J., Chen, N., Makhijani, P., Winer, S., Furman, D., & Winer, D. A. (2023) · Molecular Metabolism
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 471
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Persistent microbiome alterations modulate the rate of post-dieting weight regain
Thaiss, C. A., Itav, S., Rothschild, D., Meijer, M. T., Levy, M., Moresi, C., Dohnalová, L., Braverman, S., Rozin, S., Malitsky, S., et al. (2016) · Nature
Gut microbiota and healthRegulation of Appetite and Obesity
Cited by 471
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Patterns of Cis Regulatory Variation in Diverse Human Populations
Stranger, B. E., Montgomery, S. B., Dimas, A. S., Parts, L., Stegle, O., Ingle, C. E., Sekowska, M., Smith, G. D., Evans, D., Gutierrez-Arcelus, M., et al. (2012) · PLoS Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 470
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Functional Interference between Hypoxia and Dioxin Signal Transduction Pathways: Competition for Recruitment of the Arnt Transcription Factor
Gradin, K., McGuire, J., Wenger, R. H., Kvietikova, I., Whitelaw, M. L., Toftgård, R., Tora, L., Gassmann, M., & Poellinger, L. (1996) · Molecular and Cellular Biology
Cancer, Hypoxia, and MetabolismToxic Organic Pollutants Impact
Cited by 470
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