Most cited biochemistry, genetics and molecular biology papers
- Verified
Genetic Elimination of Suppressor of Fused Reveals an Essential Repressor Function in the Mammalian Hedgehog Signaling Pathway
Svärd, J., Henricson, K. H., Persson-Lek, M., Rozell, B., Lauth, M., Bergström, Å., Ericson, J., Toftgård, R., & Teglund, S. (2006) · Developmental Cell
Hedgehog Signaling Pathway StudiesWnt/β-catenin signaling in development and cancer
Cited by 468
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From single-cell to cell-pool transcriptomes: Stochasticity in gene expression and RNA splicing
Marinov, G. K., Williams, B. A., McCue, K., Schroth, G. P., Gertz, J., Myers, R. M., & Wold, B. J. (2014) · Genome Research
Single-cell and spatial transcriptomicsRNA Research and Splicing
Cited by 468
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Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals
Boden, G., Duan, X., Homko, C., Molina, E. J., Song, W., Perez, O., Cheung, P., & Merali, S. (2008) · Diabetes
Endoplasmic Reticulum Stress and DiseaseAdipokines, Inflammation, and Metabolic Diseases
Cited by 468
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Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner
Frank, M., Duvezin-Caubet, S., Koob, S., Occhipinti, A., Jagasia, R., Petcherski, A., Ruonala, M. O., Priault, M., Salin, B., & Reichert, A. S. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Autophagy in Disease and TherapyMitochondrial Function and Pathology
Cited by 468
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BCFtools/csq: haplotype-aware variant consequences
Danecek, P., & McCarthy, S. A. (2017) · Bioinformatics
Genomics and Rare DiseasesGenomics and Phylogenetic Studies
Cited by 468
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Proline hydroxylation and gene expression
Kaelin, W. G. (2005) · Annual Review of Biochemistry
Cancer, Hypoxia, and MetabolismMetal-Catalyzed Oxygenation Mechanisms
Cited by 468
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Sex, body mass index, and dietary fiber intake influence the human gut microbiome
Dominianni, C., Sinha, R., Goedert, J. J., Pei, Z., Yang, L., Hayes, R. B., & Ahn, J. (2015) · PLOS ONE
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 468
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Data Normalization Strategies for MicroRNA Quantification
Schwarzenbach, H., da Silva, A. M., Calin, G., & Pantel, K. (2015) · Clinical Chemistry
Molecular Biology Techniques and ApplicationsMicroRNA in disease regulation
Cited by 468
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A Processive Single-Headed Motor: Kinesin Superfamily Protein KIF1A
Okada, Y., & Hirokawa, N. (1999) · Science
Microtubule and mitosis dynamicsAdvanced Fluorescence Microscopy Techniques
Cited by 468
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The ParaHox gene cluster is an evolutionary sister of the Hox gene cluster
Brooke, N. M., Garcia-Fernàndez, J., & Holland, P. W. H. (1998) · Nature
Developmental Biology and Gene RegulationChromosomal and Genetic Variations
Cited by 468
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Tumours with PI3K activation are resistant to dietary restriction
Kalaany, N. Y., & Sabatini, D. M. (2009) · Nature
PI3K/AKT/mTOR signaling in cancerDietary Effects on Health
Cited by 468
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MYC degradation
Farrell, A. S., & Sears, R. C. (2014) · Cold Spring Harbor Perspectives in Medicine
Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways
Cited by 468
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Rank–rank hypergeometric overlap: identification of statistically significant overlap between gene-expression signatures
Plaisier, S. B., Taschereau, R., Wong, J. A., & Graeber, T. G. (2010) · Nucleic Acids Research
Bioinformatics and Genomic NetworksGene expression and cancer classification
Cited by 468
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Global Iron-dependent Gene Regulation in Escherichia coli
McHugh, J. P., Rodríguez-Quiñones, F., Abdul-Tehrani, H., Svistunenko, D. A., Poole, R. K., Cooper, C. E., & Andrews, S. C. (2003) · Journal of Biological Chemistry
Bacterial Genetics and BiotechnologyIron Metabolism and Disorders
Cited by 468
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The quest to slow ageing through drug discovery
Partridge, L., Fuentealba, M., & Kennedy, B. K. (2020) · Nature Reviews Drug Discovery
Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine
Cited by 468
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Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs
Zhang, Y., Zhang, X., Shi, J., Tuorto, F., Li, X., Liu, Y., Liebers, R., Zhang, L., Qu, Y., Qian, J., et al. (2018) · Nature Cell Biology
RNA modifications and cancerEpigenetics and DNA Methylation
Cited by 468
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Microbiome-based therapeutics
Sorbara, M. T., & Pamer, E. G. (2022) · Nature Reviews Microbiology
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 468
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ATM-dependent phosphorylation of nibrin in response to radiation exposure
Gatei, M., Young, D., Cerosaletti, K. M., Desai-Mehta, A., Spring, K., Kozlov, S., Lavin, M. F., Gatti, R. A., Concannon, P., & Khanna, K. (2000) · Nature Genetics
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 468
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Transposable elements in mammals promote regulatory variation and diversification of genes with specialized functions
van de Lagemaat, L. N., Landry, J.-R., Mager, D. L., & Medstrand, P. (2003) · Trends in Genetics
Chromosomal and Genetic VariationsGenomics and Chromatin Dynamics
Cited by 468
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Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass
Spinelli, J. B., Yoon, H., Ringel, A. E., Jeanfavre, S., Clish, C. B., & Haigis, M. C. (2017) · Science
Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism
Cited by 468
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Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl
Busslinger, G. A., Stocsits, R. R., van der Lelij, P., Axelsson, E., Tedeschi, A., Galjart, N., & Peters, J.-M. (2017) · Nature
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 468
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Single nucleotide polymorphism arrays: a decade of biological, computational and technological advances
LaFramboise, T. (2009) · Nucleic Acids Research
Genomic variations and chromosomal abnormalitiesGenetic Associations and Epidemiology
Cited by 467
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Circuitry and Dynamics of Human Transcription Factor Regulatory Networks
Neph, S., Stergachis, A. B., Reynolds, A., Sandstrom, R., Borenstein, E., & Stamatoyannopoulos, J. A. (2012) · Cell
Genomics and Chromatin DynamicsGene Regulatory Network Analysis
Cited by 467
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Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells
Sturgeon, C. M., Ditadi, A., Awong, G., Kennedy, M., & Keller, G. (2014) · Nature Biotechnology
Pluripotent Stem Cells ResearchHematopoietic Stem Cell Transplantation
Cited by 467
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