Most cited biochemistry, genetics and molecular biology papers
- Verified
Improving the phenotype predictions of a yeast genome‐scale metabolic model by incorporating enzymatic constraints
Sánchez, B. J., Zhang, C., Nilsson, A., Lahtvee, P., Kerkhoven, E. J., & Nielsen, J. (2017) · Molecular Systems Biology
Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis
Cited by 466
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Selective targeting of an antioxidant to mitochondria
Smith, R. A. J., Porteous, C. M., Coulter, C. V., & Murphy, M. P. (1999) · European Journal of Biochemistry
Mitochondrial Function and PathologyAntioxidant Activity and Oxidative Stress
Cited by 466
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Evolution of high-level resistance during low-level antibiotic exposure
Wistrand-Yuen, E., Knopp, M., Hjort, K., Koskiniemi, S., Berg, O. G., & Andersson, D. I. (2018) · Nature Communications
Evolution and Genetic DynamicsAntibiotic Resistance in Bacteria
Cited by 466
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Interlinked Fast and Slow Positive Feedback Loops Drive Reliable Cell Decisions
Brandman, O., Ferrell, J. E., Li, R., & Meyer, T. (2005) · Science
Gene Regulatory Network Analysisstochastic dynamics and bifurcation
Cited by 466
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The extracellular matrix protects Pseudomonas aeruginosa biofilms by limiting the penetration of tobramycin
Tseng, B. S., Zhang, W., Harrison, J. J., Quach, T. P., Song, J. L., Penterman, J., Singh, P. K., Chopp, D. L., Packman, A. I., & Parsek, M. R. (2013) · Environmental Microbiology
Bacterial biofilms and quorum sensingAntifungal resistance and susceptibility
Cited by 466
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Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development
Reijns, M. A. M., Rabe, B., Rigby, R. E., Mill, P., Astell, K. R., Lettice, L. A., Boyle, S., Leitch, A., Keighren, M., Kilanowski, F., et al. (2012) · Cell
DNA Repair MechanismsDNA and Nucleic Acid Chemistry
Cited by 466
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Modifications in an Emergency: The Role of N1-Methylpseudouridine in COVID-19 Vaccines
Nance, K. D., & Meier, J. L. (2021) · ACS Central Science
RNA modifications and cancerRNA and protein synthesis mechanisms
Cited by 466
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Donor age and cell passage affects differentiation potential of murine bone marrow-derived stem cells
Kretlow, J. D., Jin, Y.-Q., Liu, W., Zhang, W. J., Hong, T.-H., Zhou, G., Baggett, L. S., Mikos, A. G., & Cao, Y. (2008) · BMC Cell Biology
Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation
Cited by 466
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A vegan or vegetarian diet substantially alters the human colonic faecal microbiota
Zimmer, J., Lange, B., Frick, J.-S., Sauer, H., Zimmermann, K., Schwiertz, A., Rusch, K., Klosterhalfen, S., & Enck, P. (2012) · European Journal of Clinical Nutrition
Gut microbiota and healthNutritional Studies and Diet
Cited by 465
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Accelerating Novel Candidate Gene Discovery in Neurogenetic Disorders via Whole-Exome Sequencing of Prescreened Multiplex Consanguineous Families
Alazami, A. M., Patel, N., Shamseldin, H. E., Anazi, S., Al-Dosari, M. S., Alzahrani, F., Hijazi, H., Alshammari, M., Aldahmesh, M. A., Salih, M. A., et al. (2015) · Cell Reports
Genomics and Rare DiseasesHereditary Neurological Disorders
Cited by 465
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BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment
Winter, G. E., Mayer, A., Buckley, D. L., Erb, M. A., Roderick, J. E., Vittori, S., Reyes, J. M., di Iulio, J., Souza, A., Ott, C. J., et al. (2017) · Molecular Cell
Protein Degradation and InhibitorsGenomics and Chromatin Dynamics
Cited by 465
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Cancer and the gut microbiota: An unexpected link
Zitvogel, L., Galluzzi, L., Viaud, S., Vétizou, M., Daillère, R., Merad, M., & Kroemer, G. (2015) · Science Translational Medicine
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 465
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Over-expression of facilitative glucose transporter genes in human cancer
Yamamoto, T., Seino, Y., Fukumoto, H., Koh, G., Yano, H., Inagaki, N., Yamada, Y., Inoue, K., Manabe, T., & Imura, H. (1990) · Biochemical and Biophysical Research Communications
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 465
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Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models
Takahashi, N., Duprez, L., Grootjans, S., Cauwels, A., Nerinckx, W., DuHadaway, J. B., Goossens, V, Roelandt, R., Van Hauwermeiren, F., Libert, C., et al. (2012) · Cell Death & Disease
Cell death mechanisms and regulationNF-κB Signaling Pathways
Cited by 465
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Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance
Tremblay, F., Brûlé, S., Hee Um, S., Li, Y., Masuda, K., Roden, M., Sun, X. J., Krebs, M., Polakiewicz, R. D., Thomas, G., et al. (2007) · Proceedings of the National Academy of Sciences
Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer
Cited by 465
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Erratum: Targeting the NLRP3 inflammasome in inflammatory diseases
Mangan, M. S. J., Olhava, E. J., Roush, W. R., Seidel, H. M., Glick, G. D., & Latz, E. (2018) · Nature Reviews Drug Discovery
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 465
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Fusobacterium in Colonic Flora and Molecular Features of Colorectal Carcinoma
Tahara, T., Yamamoto, E., Suzuki, H., Maruyama, R., Chung, W., Garriga, J., Jelinek, J., Yamano, H.-O., Sugai, T., An, B., et al. (2014) · Cancer Research
Gut microbiota and healthGenetic factors in colorectal cancer
Cited by 465
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RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response
Maréchal, A., & Zou, L. (2015) · Cell Research
DNA Repair MechanismsUbiquitin and proteasome pathways
Cited by 465
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Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing
Replogle, J. M., Norman, T. M., Xu, A., Hussmann, J. A., Chen, J., Cogan, J. Z., Meer, E. J., Terry, J. M., Riordan, D. P., Srinivas, N., et al. (2020) · Nature Biotechnology
CRISPR and Genetic EngineeringSingle-cell and spatial transcriptomics
Cited by 465
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Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing
Crosetto, N., Mitra, A., Silva, M. J., Bienko, M., Dojer, N., Wang, Q., Karaca, E., Chiarle, R., Skrzypczak, M., Ginalski, K., et al. (2013) · Nature Methods
DNA Repair MechanismsGenomic variations and chromosomal abnormalities
Cited by 465
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Cancer Stem Cell Metabolism
Peiris-Pagès, M., Martinez-Outschoorn, U. E., Pestell, R. G., Sotgia, F., & Lisanti, M. P. (2016) · Breast Cancer Research
Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis
Cited by 465
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The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines
Eizirik, D. L., Sammeth, M., Bouckenooghe, T., Bottu, G., Sisino, G., Igoillo-Esteve, M., Ortis, F., Santin, I., Colli, M. L., Barthson, J., et al. (2012) · PLoS Genetics
Diabetes and associated disordersPancreatic function and diabetes
Cited by 465
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Prebiotic Effects of Wheat Arabinoxylan Related to the Increase in Bifidobacteria, Roseburia and Bacteroides/Prevotella in Diet-Induced Obese Mice
Neyrinck, A. M., Possemiers, S., Druart, C., Van de Wiele, T., De Backer, F., Cani, P. D., Larondelle, Y., & Delzenne, N. M. (2011) · PLoS ONE
Gut microbiota and healthMicrobial Metabolites in Food Biotechnology
Cited by 465
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Identifying Causal Variants at Loci with Multiple Signals of Association
Hormozdiari, F., Kostem, E., Kang, E. Y., Pasaniuc, B., & Eskin, E. (2014) · Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 465
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