Most cited biochemistry, genetics and molecular biology papers
- Verified
Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites
Takei, N., Inamura, N., Kawamura, M., Namba, H., Hara, K., Yonezawa, K., & Nawa, H. (2004) · The Journal of Neuroscience
RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancer
Cited by 442
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Adipose Tissue-Derived Multipotent Stromal Cells Have a Higher Immunomodulatory Capacity Than Their Bone Marrow-Derived Counterparts
Melief, S. M., Zwaginga, J. J., Fibbe, W. E., & Roelofs, H. (2013) · Stem Cells Translational Medicine
Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation
Cited by 442
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Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease
Loots, G. G., Kneissel, M., Keller, H., Baptist, M., Chang, J., Collette, N. M., Ovcharenko, D., Plajzer-Frick, I., & Rubin, E. M. (2005) · Genome Research
Bone Metabolism and DiseasesGenomics and Chromatin Dynamics
Cited by 442
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Crystal structure of a photoactivated deprotonated intermediate of rhodopsin
Salom, D., Lodowski, D. T., Stenkamp, R. E., Trong, I. L., Golczak, M., Jastrzebska, B., Harris, T., Ballesteros, J. A., & Palczewski, K. (2006) · Proceedings of the National Academy of Sciences
Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research
Cited by 442
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Sex differences in biological aging with a focus on human studies
Hägg, S., & Jylhävä, J. (2021) · eLife
Genetics, Aging, and Longevity in Model OrganismsSex and Gender in Healthcare
Cited by 442
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The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs
Groves, M. R., Hanlon, N., Turowski, P., Hemmings, B. A., & Barford, D. (1999) · Cell
Protein Structure and DynamicsProtein Tyrosine Phosphatases
Cited by 442
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The role of NFAT in osteoclast formation
TAKAYANAGI, H. (2007) · Annals of the New York Academy of Sciences
Bone Metabolism and DiseasesSignaling Pathways in Disease
Cited by 442
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Mammalian stress response: induction of the glucose-regulated protein family
Lee, A. S. (1992) · Current Opinion in Cell Biology
Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research
Cited by 442
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Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours
Garcia-Bermudez, J., Baudrier, L., La, K., Zhu, X. G., Fidelin, J., Sviderskiy, V. O., Papagiannakopoulos, T., Molina, H., Snuderl, M., Lewis, C. A., et al. (2018) · Nature Cell Biology
Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism
Cited by 442
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Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity
Hopp, K., Ward, C. J., Hommerding, C. J., Nasr, S. H., Tuan, H.-F., Gainullin, V. G., Rossetti, S., Torres, V. E., & Harris, P. C. (2012) · Journal of Clinical Investigation
Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances
Cited by 442
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The mouse ascending: perspectives for human-disease models
Rosenthal, N., & Brown, S. (2007) · Nature Cell Biology
Animal Genetics and ReproductionAnimal testing and alternatives
Cited by 442
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Using control genes to correct for unwanted variation in microarray data
Gagnon-Bartsch, J. A., & Speed, T. P. (2012) · Biostatistics
Gene expression and cancer classificationBioinformatics and Genomic Networks
Cited by 442
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Conditional Activation of Akt in Adult Skeletal Muscle Induces Rapid Hypertrophy
Lai, K.-M. V., Gonzalez, M., Poueymirou, W. T., Kline, W. O., Na, E., Zlotchenko, E., Stitt, T. N., Economides, A. N., Yancopoulos, G. D., & Glass, D. J. (2004) · Molecular and Cellular Biology
Muscle Physiology and DisordersMuscle metabolism and nutrition
Cited by 442
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Quantifying prion disease penetrance using large population control cohorts
Minikel, E. V., Vallabh, S. M., Lek, M., Estrada, K., Samocha, K. E., Sathirapongsasuti, J. F., McLean, C. Y., Tung, J. Y., Yu, L. P. C., Gambetti, P., et al. (2016) · Science Translational Medicine
Prion Diseases and Protein MisfoldingGenomics and Rare Diseases
Cited by 442
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Docking domains and substrate-specificity determination for MAP kinases
Sharrocks, A. D., Yang, S.-H., & Galanis, A. (2000) · Trends in Biochemical Sciences
Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases
Cited by 442
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Dynamic redox control of NF-κB through glutaredoxin-regulated S-glutathionylation of inhibitory κB kinase β
Reynaert, N. L., van der Vliet, A., Guala, A. S., McGovern, T., Hristova, M., Pantano, C., Heintz, N. H., Heim, J., Ho, Y.-S., Matthews, D. E., et al. (2006) · Proceedings of the National Academy of Sciences
Redox biology and oxidative stressNF-κB Signaling Pathways
Cited by 442
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Highly Nonlinear Photodamage in Two-Photon Fluorescence Microscopy
Hopt, A., & Neher, E. (2001) · Biophysical Journal
Advanced Fluorescence Microscopy TechniquesNonlinear Optical Materials Studies
Cited by 442
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Admixture in Latin America: Geographic Structure, Phenotypic Diversity and Self-Perception of Ancestry Based on 7,342 Individuals
Ruiz-Linares, A., Adhikari, K., Acuña-Alonzo, V., Quinto-Sanchez, M., Jaramillo, C., Arias, W., Fuentes, M., Pizarro, M., Everardo, P., de Avila, F., et al. (2014) · PLoS Genetics
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 442
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Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors
Wang, X., Wang, Y., Wu, X., Wang, J., Wang, Y., Qiu, Z., Chang, T., Huang, H., Lin, R.-J., & Yee, J.-K. (2015) · Nature Biotechnology
CRISPR and Genetic EngineeringVirus-based gene therapy research
Cited by 442
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Human 5′ UTR design and variant effect prediction from a massively parallel translation assay
Sample, P. J., Wang, B., Reid, D. W., Presnyak, V., McFadyen, I. J., Morris, D. R., & Seelig, G. (2019) · Nature Biotechnology
RNA and protein synthesis mechanismsRNA Research and Splicing
Cited by 442
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An atlas of human metabolism
Robinson, J. L., Kocabaş, P., Wang, H., Cholley, P.-E., Cook, D., Nilsson, A., Anton, M., Ferreira, R., Domenzain, I., Billa, V., et al. (2020) · Science Signaling
Microbial Metabolic Engineering and BioproductionBioinformatics and Genomic Networks
Cited by 442
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Calcineurin acts through the CRZ1/TCN1-encoded transcription factor to regulate gene expression in yeast
Stathopoulos, A. M., & Cyert, M. S. (1997) · Genes & Development
Fungal and yeast genetics researchSignaling Pathways in Disease
Cited by 442
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Tissue/planar cell polarity in vertebrates: new insights and new questions
Wang, Y., & Nathans, J. (2007) · Development
Developmental Biology and Gene RegulationGenetic and Kidney Cyst Diseases
Cited by 442
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Meta-analysis of 2,104 trios provides support for 10 new genes for intellectual disability
Lelieveld, S. H., Reijnders, M. R. F., Pfundt, R., Yntema, H. G., Kamsteeg, E.-J., de Vries, P., de Vries, B. B. A., Willemsen, M. H., Kleefstra, T., Löhner, K., et al. (2016) · Nature Neuroscience
Genomics and Rare DiseasesGenetics and Neurodevelopmental Disorders
Cited by 442
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