Most cited biochemistry, genetics and molecular biology papers
- Verified
The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
Humke, E. W., Dorn, K. V., Milenkovic, L., Scott, M. P., & Rohatgi, R. (2010) · Genes & Development
Hedgehog Signaling Pathway StudiesGenetic and Kidney Cyst Diseases
Cited by 444
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Quality control in the secretory pathway: retention of a misfolded viral membrane glycoprotein involves cycling between the ER, intermediate compartment, and Golgi apparatus.
Hammond, C., & Helenius, A. (1994) · The Journal of cell biology
Endoplasmic Reticulum Stress and DiseaseCellular transport and secretion
Cited by 443
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Specialized DNA Polymerases, Cellular Survival, and the Genesis of Mutations
Friedberg, E. C., Wagner, R., & Radman, M. (2002) · Science
DNA Repair MechanismsEvolution and Genetic Dynamics
Cited by 443
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The Commensal Microbiota and Enteropathogens in the Pathogenesis of Inflammatory Bowel Diseases
Chassaing, B., & Darfeuille–Michaud, A. (2011) · Gastroenterology
Gut microbiota and healthInflammatory Bowel Disease
Cited by 443
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Systemic availability and metabolism of colonic‐derived short‐chain fatty acids in healthy subjects: a stable isotope study
Boets, E., Gomand, S. V., Deroover, L., Preston, T., Vermeulen, K., De Preter, V., Hamer, H. M., Van den Mooter, G., De Vuyst, L., Courtin, C. M., et al. (2017) · The Journal of Physiology
Gut microbiota and healthMicrobial Metabolites in Food Biotechnology
Cited by 443
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Energy Metabolism of the Osteoblast: Implications for Osteoporosis
Lee, W.-C., Guntur, A. R., Long, F., & Rosen, C. J. (2017) · Endocrine Reviews
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 443
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Trans-Synaptic Transmission of Vesicular Wnt Signals through Evi/Wntless
Korkut, C., Ataman, B., Ramachandran, P., Ashley, J., Barria, R., Gherbesi, N., & Budnik, V. (2009) · Cell
Wnt/β-catenin signaling in development and cancerCellular transport and secretion
Cited by 443
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Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis
Tang, M., Pham, P., Shen, X., Taylor, J.-S., O'Donnell, M., Woodgate, R., & Goodman, M. F. (2000) · Nature
DNA Repair MechanismsBacterial Genetics and Biotechnology
Cited by 443
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Reactivation of developmentally silenced globin genes by forced chromatin looping
Deng, W., Rupon, J. W., Krivega, I., Breda, L., Motta, I., Jahn, K. S., Reik, A., Gregory, P. D., Rivella, S., Dean, A., et al. (2014) · Cell
Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders
Cited by 443
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Analysis of copy number variations at 15 schizophrenia-associated loci
Rees, E., Walters, J. T. R., Georgieva, L., Isles, A. R., Chambert, K. D., Richards, A. L., Mahoney-Davies, G., Legge, S. E., Moran, J. L., McCarroll, S. A., et al. (2014) · British Journal of Psychiatry
Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment
Cited by 443
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NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder
Alcocer-Gómez, E., de Miguel, M., Casas-Barquero, N., Núñez-Vasco, J., Sánchez-Alcazar, J. A., Fernández-Rodríguez, A., & Cordero, M. D. (2014) · Brain, Behavior, and Immunity
Inflammasome and immune disordersTryptophan and brain disorders
Cited by 443
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Heme oxygenase–1, oxidation, inflammation, and atherosclerosis
Araujo, J. A., Zhang, M., & Yin, F. (2012) · Frontiers in Pharmacology
Heme Oxygenase-1 and Carbon MonoxideAtherosclerosis and Cardiovascular Diseases
Cited by 443
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Combined Linkage and Association Sib-Pair Analysis for Quantitative Traits
Fulker, D. W., Cherny, S. S., Sham, P. C., & Hewitt, J. K. (1999) · The American Journal of Human Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 443
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Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2
Qing, K., Mah, C., Hansen, J., Zhou, S., Dwarki, V., & Srivastava, A. (1999) · Nature Medicine
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 443
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Mapping the genomic landscape of CRISPR-Cas9 cleavage
Cameron, P., Fuller, C. K., Donohoue, P. D., Jones, B. N., Thompson, M. S., Carter, M. M., Gradia, S., Vidal, B., Garner, E., Slorach, E. M., et al. (2017) · Nature Methods
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 443
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Procedures to Estimate Fecundity of Wild Collected Marine Fish in Relation to Fish Reproductive Strategy
Murua, H., Kraus, G., Saborido-Rey, F., Wittames, P. R., Thorsen, A., & Junquera, S. (2003) · Journal of Northwest Atlantic Fishery Science
Reproductive biology and impacts on aquatic speciesMarine and fisheries research
Cited by 443
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Butyrate and other short-chain fatty acids as modulators of immunity: What relevance for health?
Meijer, K., de Vos, P., & Priebe, M. G. (2010) · Current Opinion in Clinical Nutrition and Metabolic Care
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 443
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Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity
Atkins, C., Liu, Q., Minthorn, E., Zhang, S.-Y., Figueroa, D. J., Moss, K., Stanley, T. B., Sanders, B., Goetz, A., Gaul, N., et al. (2013) · Cancer Research
Endoplasmic Reticulum Stress and DiseasePI3K/AKT/mTOR signaling in cancer
Cited by 443
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GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1α
Lerin, C., Rodgers, J. T., Kalume, D. E., Kim, S.-H., Pandey, A., & Puigserver, P. (2006) · Cell Metabolism
Metabolism, Diabetes, and CancerPeroxisome Proliferator-Activated Receptors
Cited by 443
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Emergence of robust growth laws from optimal regulation of ribosome synthesis
Scott, M., Klumpp, S., Mateescu, E. M., & Hwa, T. (2014) · Molecular Systems Biology
RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology
Cited by 443
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Hybrid necrosis: autoimmunity as a potential gene-flow barrier in plant species
Bomblies, K., & Weigel, D. (2007) · Nature Reviews Genetics
Chromosomal and Genetic VariationsEvolution and Genetic Dynamics
Cited by 443
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The principal target of rapamycin‐induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.
Pearson, R. B., Dennis, P. B., Han, J. W., Williamson, N. A., Kozma, S. C., Wettenhall, R. E., & Thomas, G. (1995) · The EMBO Journal
PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling
Cited by 443
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mTOR Kinase Inhibition Causes Feedback-Dependent Biphasic Regulation of AKT Signaling
Rodrik-Outmezguine, V. S., Chandarlapaty, S., Pagano, N. C., Poulikakos, P. I., Scaltriti, M., Moskatel, E., Baselga, J., Guichard, S., & Rosen, N. (2011) · Cancer Discovery
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 442
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Mitochondrial DNA–Deletion Mutations Accumulate Intracellularly to Detrimental Levels in Aged Human Skeletal Muscle Fibers
Bua, E., Johnson, J., Herbst, A., Delong, B., McKenzie, D., Salamat, S., & Aiken, J. M. (2006) · The American Journal of Human Genetics
Mitochondrial Function and PathologyMuscle Physiology and Disorders
Cited by 442
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