Most cited biochemistry, genetics and molecular biology papers
- Verified
Protein posttranslational modifications in health and diseases: Functions, regulatory mechanisms, and therapeutic implications
Zhong, Q., Xiao, X., Qiu, Y., Xu, Z., Chen, C., Chong, B., Zhao, X., Hai, S., Li, S., An, Z., et al. (2023) · MedComm
Ubiquitin and proteasome pathwaysCancer-related gene regulation
Cited by 442
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Endocrine fibroblast growth factors 15/19 and 21: from feast to famine
Potthoff, M. J., Kliewer, S. A., & Mangelsdorf, D. J. (2012) · Genes & Development
Fibroblast Growth Factor ResearchGDF15 and Related Biomarkers
Cited by 442
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Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., et al. (2018) · Nature Genetics
Genetic Associations and EpidemiologyGenomics and Rare Diseases
Cited by 442
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Genome-wide patterns of population structure and admixture among Hispanic/Latino populations
Bryc, K., Velez, C., Karafet, T., Moreno-Estrada, A., Reynolds, A., Auton, A., Hammer, M., Bustamante, C. D., & Ostrer, H. (2010) · Proceedings of the National Academy of Sciences
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 442
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Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles
Yao, R.-Q., Ren, C., Xia, Z.-F., & Yao, Y.-M. (2021) · Autophagy
Autophagy in Disease and TherapyUbiquitin and proteasome pathways
Cited by 441
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Mitochondrial Involvement in Post-Tetanic Potentiation of Synaptic Transmission
Tang, Y.-G., & Zucker, R. S. (1997) · Neuron
Mitochondrial Function and PathologyNeuroscience and Neuropharmacology Research
Cited by 441
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Endoplasmic reticulum dysfunction in neurological disease
Roussel, B. D., Kruppa, A. J., Miranda, E., Crowther, D. C., Lomas, D. A., & Marciniak, S. J. (2013) · The Lancet Neurology
Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research
Cited by 441
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Structure of a unique binuclear manganese cluster in arginase
Kanyo, Z. F., Scolnick, L. R., Ash, D. E., & Christianson, D. W. (1996) · Nature
Enzyme Structure and FunctionAmino Acid Enzymes and Metabolism
Cited by 441
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A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells
Ma, C., Fan, R., Ahmad, H., Shi, Q., Comin-Anduix, B., Chodon, T., Koya, R. C., Liu, C.-C., Kwong, G. A., Radu, C. G., et al. (2011) · Nature Medicine
Advanced Biosensing Techniques and ApplicationsMicrofluidic and Capillary Electrophoresis Applications
Cited by 441
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A complete reference genome improves analysis of human genetic variation
Aganezov, S., Yan, S. M., Soto, D. C., Kirsche, M., Zarate, S., Avdeyev, P., Taylor, D. J., Shafin, K., Shumate, A., Xiao, C., et al. (2022) · Science
Genomics and Phylogenetic StudiesGenomic variations and chromosomal abnormalities
Cited by 441
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Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes
Agarwal, A., Wu, P.-H., Hughes, E. G., Fukaya, M., Tischfield, M. A., Langseth, A. J., Wirtz, D., & Bergles, D. E. (2017) · Neuron
Mitochondrial Function and PathologyNeuroscience and Neuropharmacology Research
Cited by 441
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Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities
Jolma, A., Kivioja, T., Toivonen, J., Cheng, L., Wei, G., Enge, M., Taipale, M., Vaquerizas, J. M., Yan, J., Sillanpää, M. J., et al. (2010) · Genome Research
Genomics and Chromatin DynamicsAdvanced biosensing and bioanalysis techniques
Cited by 441
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Using high-resolution variant frequencies to empower clinical genome interpretation
Whiffin, N., Minikel, E., Walsh, R., O’Donnell-Luria, A. H., Karczewski, K., Ing, A. Y., Barton, P. J. R., Funke, B., Cook, S. A., MacArthur, D., et al. (2017) · Genetics in Medicine
Genomics and Rare DiseasesGenetic Associations and Epidemiology
Cited by 441
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Eliciting priors and relaxing the single causal variant assumption in colocalisation analyses
Wallace, C. (2020) · PLOS Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 441
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Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase
Gandhi, R., Gillespie, P. J., & Hirano, T. (2006) · Current Biology
Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics
Cited by 441
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PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression.
Liu, W., Tanasa, B., Tyurina, O. V., Zhou, T. Y., Gassmann, R., Liu, W. T., Ohgi, K. A., Benner, C., Garcia-Bassets, I., Aggarwal, A. K., et al. (2010) · Nature
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 441
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Redox modulation of L-type calcium channels in ferret ventricular myocytes. Dual mechanism regulation by nitric oxide and S-nitrosothiols.
Campbell, D. L., Stamler, J. S., & Strauss, H. C. (1996) · The Journal of general physiology
Ion channel regulation and functionRedox biology and oxidative stress
Cited by 441
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Altered glycolytic and oxidative capacities of skeletal muscle contribute to insulin resistance in NIDDM
Simoneau, J.-A., & Kelley, D. E. (1997) · Journal of Applied Physiology
Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins
Cited by 441
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High-Glucose or -Fructose Diet Cause Changes of the Gut Microbiota and Metabolic Disorders in Mice without Body Weight Change
Do, M. H., Lee, E., Oh, M.-J., Kim, Y., & Park, H.-Y. (2018) · Nutrients
Gut microbiota and healthDiet, Metabolism, and Disease
Cited by 441
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Review article: insights into colonic protein fermentation, its modulation and potential health implications
Yao, C. K., Muir, J. G., & Gibson, P. R. (2016) · Alimentary Pharmacology & Therapeutics
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 441
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Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase
Zmijewski, J. W., Banerjee, S., Bae, H., Friggeri, A., Lazarowski, E. R., & Abraham, E. (2010) · Journal of Biological Chemistry
Metabolism, Diabetes, and CancerRedox biology and oxidative stress
Cited by 441
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Efficient differentiation of hepatocytes from human embryonic stem cells exhibiting markers recapitulating liver development in vivo
Hay, D. C., Zhao, D., Fletcher, J., Hewitt, Z. A., McLean, D., Urruticoechea-Uriguen, A., Black, J. R., Elcombe, C., Ross, J. A., Wolf, R., et al. (2008) · Stem Cells
Pluripotent Stem Cells ResearchMesenchymal stem cell research
Cited by 441
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Hydroxyl radicals (•OH) are associated with titanium dioxide (TiO2) nanoparticle-induced cytotoxicity and oxidative DNA damage in fish cells
Reeves, J. F., Davies, S. J., Dodd, N. J. F., & Jha, A. N. (2008) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Carcinogens and Genotoxicity AssessmentEnvironmental Toxicology and Ecotoxicology
Cited by 441
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Refining genotype phenotype correlations in muscular dystrophies with defective glycosylation of dystroglycan
Godfrey, C., Clement, E., Mein, R., Brockington, M., Smith, J., Talim, B., Straub, V., Robb, S., Quinlivan, R., Feng, L., et al. (2007) · Brain
Muscle Physiology and DisordersGlycosylation and Glycoproteins Research
Cited by 441
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