Most cited biochemistry, genetics and molecular biology papers
- Verified
Adaptation–not by sweeps alone
Pritchard, J. K., & Di Rienzo, A. (2010) · Nature Reviews Genetics
Evolution and Genetic DynamicsGenetic diversity and population structure
Cited by 445
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Remarkable Interkingdom Conservation of Intron Positions and Massive, Lineage-Specific Intron Loss and Gain in Eukaryotic Evolution
Rogozin, I. B., Wolf, Y. I., Sorokin, A. V., Mirkin, B. G., & Koonin, E. V. (2003) · Current Biology
Chromosomal and Genetic VariationsGenomics and Phylogenetic Studies
Cited by 445
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AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer
Hong, D., Kurzrock, R., Kim, Y., Woessner, R., Younes, A., Nemunaitis, J., Fowler, N., Zhou, T., Schmidt, J., Jo, M., et al. (2015) · Science Translational Medicine
RNA Interference and Gene DeliveryCytokine Signaling Pathways and Interactions
Cited by 445
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Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males
Harrison, D. E., Strong, R., Allison, D. B., Ames, B. N., Astle, C. M., Atamna, H., Fernandez, E., Flurkey, K., Javors, M. A., Nadon, N. L., et al. (2014) · Aging Cell
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 445
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Host–microbiota maladaptation in colorectal cancer
Janney, A., Powrie, F., & Mann, E. H. (2020) · Nature
Gut microbiota and healthColorectal Cancer Treatments and Studies
Cited by 445
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Studying vertical microbiome transmission from mothers to infants by strain-level metagenomic profiling
Asnicar, F., Manara, S., Zolfo, M., Truong, D. T., Scholz, M., Armanini, F., Ferretti, P., Gorfer, V., Pedrotti, A., Tett, A., et al. (2017) · mSystems
Gut microbiota and healthInfant Nutrition and Health
Cited by 445
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An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy
Chung, A. S., Wu, X., Zhuang, G., Ngu, H., Kasman, I., Zhang, J., Vernes, J.-M., Jiang, Z., Meng, Y. G., Peale, F. V., et al. (2013) · Nature Medicine
Angiogenesis and VEGF in CancerCancer Immunotherapy and Biomarkers
Cited by 445
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Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein.
Kowal, R. C., Herz, J., Weisgraber, K. H., Mahley, R. W., Brown, M. S., & Goldstein, J. L. (1990) · Journal of Biological Chemistry
Cholesterol and Lipid MetabolismLipid metabolism and disorders
Cited by 445
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Generation of Functional Human Hepatic Endoderm From Human Induced Pluripotent Stem Cells
Sullivan, G. J., Hay, D. C., Park, I.-H., Fletcher, J., Hannoun, Z., Payne, C. M., Dalgetty, D., Black, J. R., Ross, J. A., Samuel, K., et al. (2010) · Hepatology
Pluripotent Stem Cells ResearchDrug-Induced Hepatotoxicity and Protection
Cited by 445
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LincRNA-p21 Activates p21 In cis to Promote Polycomb Target Gene Expression and to Enforce the G1/S Checkpoint
Dimitrova, N., Zamudio, J. R., Jong, R. M., Soukup, D., Resnick, R., Sarma, K., Ward, A. J., Raj, A., Lee, J. T., Sharp, P. A., et al. (2014) · Molecular Cell
Cancer-related molecular mechanisms researchCancer-related Molecular Pathways
Cited by 445
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Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity
Kinker, G. S., Greenwald, A. C., Tal, R., Orlova, Z., Cuoco, M. S., McFarland, J. M., Warren, A., Rodman, C., Roth, J. A., Bender, S. A., et al. (2020) · Nature Genetics
Single-cell and spatial transcriptomicsCancer Genomics and Diagnostics
Cited by 445
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Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons
Krishnaswami, S. R., Grindberg, R. V., Novotny, M., Venepally, P., Lacar, B., Bhutani, K., Linker, S. B., Pham, S., Erwin, J. A., Miller, J. A., et al. (2016) · Nature Protocols
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 445
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Function and regulation of the divisome for mitochondrial fission
Kraus, F., Roy, K., Pucadyil, T. J., & Ryan, M. T. (2021) · Nature
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 445
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Mobile DNA in Health and Disease
Kazazian, H. H., & Moran, J. V. (2017) · New England Journal of Medicine
Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities
Cited by 445
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Two mitofusin proteins, mammalian homologues of FZO, with distinct functions are both required for mitochondrial fusion
Eura, Y. (2003) · Journal of Biochemistry
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 445
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The roles and regulatory mechanisms of TGF-β and BMP signaling in bone and cartilage development, homeostasis and disease
Wu, M., Wu, S., Chen, W., & Li, Y.-P. (2024) · Cell Research
TGF-β signaling in diseasesBone Metabolism and Diseases
Cited by 445
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Rapid whole-genome sequencing decreases infant morbidity and cost of hospitalization
Farnaes, L., Hildreth, A., Sweeney, N. M., Clark, M. M., Chowdhury, S., Nahas, S., Cakici, J. A., Benson, W., Kaplan, R. H., Kronick, R., et al. (2018) · npj Genomic Medicine
Genomics and Rare DiseasesMetabolism and Genetic Disorders
Cited by 445
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Dysbiosis of gut microbiota and microbial metabolites in Parkinson's disease
Sun, M.-F., & Shen, Y.-Q. (2018) · Ageing Research Reviews
Gut microbiota and healthParkinson's Disease Mechanisms and Treatments
Cited by 445
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Human embryonic stem cell-derived cardiac progenitors for severe heart failure treatment: first clinical case report: Figure 1
Menasché, P., Vanneaux, V., Hagège, A., Bel, A., Cholley, B., Cacciapuoti, I., Parouchev, A., Benhamouda, N., Tachdjian, G., Tosca, L., et al. (2015) · European Heart Journal
Pluripotent Stem Cells ResearchMesenchymal stem cell research
Cited by 445
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Next-generation diagnostics and disease-gene discovery with the Exomiser
Smedley, D., Jacobsen, J. O. B., Jäger, M., Köhler, S., Holtgrewe, M., Schubach, M., Siragusa, E., Zemojtel, T., Buske, O. J., Washington, N. L., et al. (2015) · Nature Protocols
Genomics and Rare DiseasesBioinformatics and Genomic Networks
Cited by 445
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Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner
Varga, V., Helenius, J., Tanaka, K., Hyman, A. A., Tanaka, T. U., & Howard, J. (2006) · Nature Cell Biology
Microtubule and mitosis dynamicsCancer Treatment and Pharmacology
Cited by 445
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Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive
Kanduri, C., Pant, V., Loukinov, D., Pugacheva, E., Qi, C.-F., Wolffe, A., Ohlsson, R., & Lobanenkov, V. V. (2000) · Current Biology
Genetic Syndromes and ImprintingGenomics and Chromatin Dynamics
Cited by 444
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The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study
the TEDDY Study Group, Krischer, J. P., Lynch, K. F., Schatz, D. A., Ilonen, J., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J.-X., Simell, O. G., et al. (2015) · Diabetologia
Diabetes and associated disordersDiabetes Management and Research
Cited by 444
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Hepatic stellate cell lipid droplets: A specialized lipid droplet for retinoid storage
Blaner, W. S., O'Byrne, S. M., Wongsiriroj, N., Kluwe, J., D'Ambrosio, D. M., Jiang, H., Schwabe, R. F., Hillman, E. M. C., Piantedosi, R., & Libien, J. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Lipid metabolism and biosynthesisLiver physiology and pathology
Cited by 444
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