Most cited biochemistry, genetics and molecular biology papers
- Verified
DNA polymerase η is an A-T mutator in somatic hypermutation of immunoglobulin variable genes
Zeng, X., Winter, D. B., Kasmer, C., Kraemer, K. H., Lehmann, A. R., & Gearhart, P. J. (2001) · Nature Immunology
DNA Repair MechanismsT-cell and B-cell Immunology
Cited by 420
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The starvation hormone, fibroblast growth factor-21, extends lifespan in mice
Zhang, Y., Xie, Y., Berglund, E. D., Coate, K. C., He, T. T., Katafuchi, T., Xiao, G., Potthoff, M. J., Wei, W., Wan, Y., et al. (2012) · eLife
Fibroblast Growth Factor ResearchGenetics, Aging, and Longevity in Model Organisms
Cited by 420
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Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay
Yamashita, A., Ohnishi, T., Kashima, I., Taya, Y., & Ohno, S. (2001) · Genes & Development
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 420
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Understanding mitochondrial complex I assembly in health and disease
Mimaki, M., Wang, X., McKenzie, M., Thorburn, D. R., & Ryan, M. T. (2012) · Biochimica et Biophysica Acta (BBA) - Bioenergetics
Mitochondrial Function and PathologyEnzyme Structure and Function
Cited by 420
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Astrocyte intermediate filaments in CNS pathologies and regeneration
Pekny, M., & Pekna, M. (2004) · The Journal of Pathology
Skin and Cellular Biology ResearchNeuroinflammation and Neurodegeneration Mechanisms
Cited by 420
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Multidimensional Optimality of Microbial Metabolism
Schuetz, R., Zamboni, N., Zampieri, M., Heinemann, M., & Sauer, U. (2012) · Science
Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis
Cited by 420
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The Pathophysiology of Fragile X Syndrome
Penagarikano, O., Mulle, J. G., & Warren, S. T. (2007) · Annual Review of Genomics and Human Genetics
Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases
Cited by 420
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Complex regulatory effects of gut microbial short-chain fatty acids on immune tolerance and autoimmunity
Kim, C. H. (2023) · Cellular & Molecular Immunology
Gut microbiota and healthT-cell and B-cell Immunology
Cited by 420
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Coupled Ferredoxin and Crotonyl Coenzyme A (CoA) Reduction with NADH Catalyzed by the Butyryl-CoA Dehydrogenase/Etf Complex from Clostridium kluyveri
Li, F., Hinderberger, J., Seedorf, H., Zhang, J., Buckel, W., & Thauer, R. K. (2008) · Journal of Bacteriology
Metalloenzymes and iron-sulfur proteinsAnaerobic Digestion and Biogas Production
Cited by 420
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Tunneling Nanotubes Provide a Unique Conduit for Intercellular Transfer of Cellular Contents in Human Malignant Pleural Mesothelioma
Lou, E., Fujisawa, S., Morozov, A., Barlas, A., Romin, Y., Dogan, Y., Gholami, S., Moreira, A. L., Manova-Todorova, K., & Moore, M. A. S. (2012) · PLoS ONE
Extracellular vesicles in diseaseCellular Mechanics and Interactions
Cited by 420
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Reversal of Bone Loss in Mice by Nongenotropic Signaling of Sex Steroids
Kousteni, S., Chen, J.-R., Bellido, T., Han, L., Ali, A. A., O'Brien, C. A., Plotkin, L., Fu, Q., Mancino, A. T., Wen, Y., et al. (2002) · Science
Estrogen and related hormone effectsBone health and osteoporosis research
Cited by 420
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Multiple diverse ligands binding at a single protein site: A matter of pre‐existing populations
Ma, B., Shatsky, M., Wolfson, H. J., & Nussinov, R. (2002) · Protein Science
Protein Structure and DynamicsReceptor Mechanisms and Signaling
Cited by 420
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Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria
Ono, T., Isobe, K., Nakada, K., & Hayashi, J.-I. (2001) · Nature Genetics
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 420
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Oncogenic Ras and Akt signaling contribute to glioblastoma formation by differential recruitment of existing mRNAs to polysomes.
Rajasekhar, V. K., Viale, A., Socci, N. D., Wiedmann, M., Hu, X., & Holland, E. C. (2003) · Molecular Cell
PI3K/AKT/mTOR signaling in cancerRNA and protein synthesis mechanisms
Cited by 420
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Endothelial microparticles in diseases
Chironi, G. N., Boulanger, C. M., Simon, A., Dignat-George, F., Freyssinet, J.-M., & Tedgui, A. (2009) · Cell and Tissue Research
Extracellular vesicles in diseaseBlood Coagulation and Thrombosis Mechanisms
Cited by 420
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Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors
Gray, S. J., Foti, S. B., Schwartz, J. W., Bachaboina, L., Taylor-Blake, B., Coleman, J., Ehlers, M. D., Zylka, M. J., McCown, T. J., & Samulski, R. J. (2011) · Human Gene Therapy
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 420
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Mechanisms of glucocorticoid receptor signaling during inflammation
Smoak, K. A., & Cidlowski, J. A. (2004) · Mechanisms of Ageing and Development
Estrogen and related hormone effectsNF-κB Signaling Pathways
Cited by 420
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Role of Ion Channels and Transporters in Cell Migration
Schwab, A., Fabian, A., Hanley, P. J., & Stock, C. (2012) · Physiological Reviews
Ion channel regulation and functionIon Transport and Channel Regulation
Cited by 420
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Therapeutic strategies to target RAS-mutant cancers
Ryan, M. B., & Corcoran, R. B. (2018) · Nature Reviews Clinical Oncology
Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases
Cited by 420
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Parkin‐independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain
Kageyama, Y., Hoshijima, M., Seo, K., Bedja, D., Sysa‐Shah, P., Andrabi, S. A., Chen, W., Höke, A., Dawson, V. L., Dawson, T. M., et al. (2014) · The EMBO Journal
Autophagy in Disease and TherapyMitochondrial Function and Pathology
Cited by 420
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DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients
Volkmar, M., Dedeurwaerder, S., Cunha, D. A., Ndlovu, M. N., Defrance, M., Deplus, R., Calonne, E., Volkmar, U., Igoillo‐Esteve, M., Naamane, N., et al. (2012) · The EMBO Journal
Epigenetics and DNA MethylationPancreatic function and diabetes
Cited by 420
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Combined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: Combinatorial Islet Autoantibody Workshop
Verge, C. F., Stenger, D., Bonifacio, E., Colman, P. G., Pilcher, C., Bingley, P. J., & Eisenbarth, G. S. (1998) · Diabetes
Diabetes and associated disordersDiabetes Management and Research
Cited by 420
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The genomics of oxidative DNA damage, repair, and resulting mutagenesis
Poetsch, A. R. (2020) · Computational and Structural Biotechnology Journal
DNA Repair MechanismsCarcinogens and Genotoxicity Assessment
Cited by 420
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Lamellipodial Versus Filopodial Mode of the Actin Nanomachinery
Mejillano, M. R., Kojima, S.-I., Applewhite, D. A., Gertler, F. B., Svitkina, T. M., & Borisy, G. G. (2004) · Cell
Cellular Mechanics and InteractionsProtein Kinase Regulation and GTPase Signaling
Cited by 420
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