Most cited biochemistry, genetics and molecular biology papers
- Verified
SNP Calling, Genotype Calling, and Sample Allele Frequency Estimation from New-Generation Sequencing Data
Nielsen, R., Korneliussen, T., Albrechtsen, A., Li, Y., & Wang, J. (2012) · PLoS ONE
Genomics and Phylogenetic StudiesGenetic Associations and Epidemiology
Cited by 424
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Gut Microbiota-Derived Tryptophan Metabolites Maintain Gut and Systemic Homeostasis
Su, X., Gao, Y., & Yang, R. (2022) · Cells
Gut microbiota and healthTryptophan and brain disorders
Cited by 424
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Immune Responses to the Microbiota at the Intestinal Mucosal Surface
Duerkop, B. A., Vaishnava, S., & Hooper, L. V. (2009) · Immunity
Gut microbiota and healthInflammatory Bowel Disease
Cited by 424
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Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging
Andersson, D. C., Betzenhauser, M. J., Reiken, S., Meli, A. C., Umanskaya, A., Xie, W., Shiomi, T., Zalk, R., Lacampagne, A., & Marks, A. R. (2011) · Cell Metabolism
Muscle Physiology and DisordersIon channel regulation and function
Cited by 424
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Therapeutic potential of the endocrine fibroblast growth factors FGF19, FGF21 and FGF23
Degirolamo, C., Sabbà, C., & Moschetta, A. (2016) · Nature Reviews Drug Discovery
Fibroblast Growth Factor ResearchParathyroid Disorders and Treatments
Cited by 424
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Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction
Wilks, A. F. (1989) · Proceedings of the National Academy of Sciences
Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases
Cited by 424
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Paternally induced transgenerational inheritance of susceptibility to diabetes in mammals
Wei, Y., Yang, C.-R., Wei, Y.-P., Zhao, Z.-A., Hou, Y., Schatten, H., & Sun, Q.-Y. (2014) · Proceedings of the National Academy of Sciences
Epigenetics and DNA MethylationBirth, Development, and Health
Cited by 423
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Huntingtin functions as a scaffold for selective macroautophagy
Rui, Y.-N., Xu, Z., Patel, B., Chen, Z., Chen, D., Tito, A., David, G., Sun, Y., Stimming, E. F., Bellen, H. J., et al. (2015) · Nature Cell Biology
Autophagy in Disease and TherapyGenetic Neurodegenerative Diseases
Cited by 423
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Regulation of life span by the gut microbiota in the short-lived African turquoise killifish
Smith, P., Willemsen, D., Popkes, M., Metge, F., Gandiwa, E., Reichard, M., & Valenzano, D. R. (2017) · eLife
Genetics, Aging, and Longevity in Model OrganismsGut microbiota and health
Cited by 423
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Cellular and molecular mechanisms underlying age-related skeletal muscle wasting and weakness
Ryall, J. G., Schertzer, J. D., & Lynch, G. S. (2008) · Biogerontology
Muscle Physiology and DisordersNutrition and Health in Aging
Cited by 423
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CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis
Hao, J.-W., Wang, J., Guo, H., Zhao, Y.-Y., Sun, H.-H., Li, Y.-F., Lai, X.-Y., Zhao, N., Wang, X., Xie, C., et al. (2020) · Nature Communications
Lipid metabolism and biosynthesisCaveolin-1 and cellular processes
Cited by 423
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A model of human tumor dormancy: an angiogenic switch from the nonangiogenic phenotype
Naumov, G. N., Bender, E., Zurakowski, D., Kang, S.-Y., Sampson, D., Flynn, E., Watnick, R. S., Straume, O., Akslen, L. A., Folkman, J., et al. (2006) · JNCI: Journal of the National Cancer Institute
Angiogenesis and VEGF in CancerCancer Cells and Metastasis
Cited by 423
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A de novo convergence of autism genetics and molecular neuroscience
Krumm, N., O’Roak, B. J., Shendure, J., & Eichler, E. E. (2014) · Trends in Neurosciences
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 423
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Reduced Neutrophil Count in People of African Descent Is Due To a Regulatory Variant in the Duffy Antigen Receptor for Chemokines Gene
Reich, D., Nalls, M. A., Kao, W. H. L., Akylbekova, E. L., Tandon, A., Patterson, N., Mullikin, J., Hsueh, W.-C., Cheng, C.-Y., Coresh, J., et al. (2009) · PLoS Genetics
Genetic Associations and EpidemiologyRace, Genetics, and Society
Cited by 423
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Analysis of zinc binding sites in protein crystal structures
Alberts, I. L., Nadassy, K., & Wodak, S. J. (1998) · Protein Science
Enzyme Structure and FunctionProtein Structure and Dynamics
Cited by 423
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Molecular and spatial signatures of mouse brain aging at single-cell resolution
Allen, W. E., Blosser, T. R., Sullivan, Z. A., Dulac, C., & Zhuang, X. (2023) · Cell
Single-cell and spatial transcriptomicsNeuroinflammation and Neurodegeneration Mechanisms
Cited by 423
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The exocyst is a Ral effector complex
Moskalenko, S., Henry, D. O., Rosse, C., Mirey, G., Camonis, J. H., & White, M. A. (2002) · Nature Cell Biology
Cellular transport and secretionProtein Kinase Regulation and GTPase Signaling
Cited by 423
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Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity
Palmer, A. K., Tchkonia, T., LeBrasseur, N. K., Chini, E. N., Xu, M., & Kirkland, J. L. (2015) · Diabetes
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 423
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Regulation of the p300 HAT domain via a novel activation loop
Thompson, P. R., Wang, D., Wang, L., Fulco, M., Pediconi, N., Zhang, D., An, W., Ge, Q., Roeder, R. G., Wong, J., et al. (2004) · Nature Structural & Molecular Biology
Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research
Cited by 423
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Mutational Analysis of Hsp90 Function: Interactions with a Steroid Receptor and a Protein Kinase
Nathan, D. F., & Lindquist, S. (1995) · Molecular and Cellular Biology
Heat shock proteins researchFungal and yeast genetics research
Cited by 423
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AMPK β Subunit Targets Metabolic Stress Sensing to Glycogen
Polekhina, G., Gupta, A., Michell, B. J., van Denderen, B., Murthy, S., Feil, S. C., Jennings, I. G., Campbell, D. J., Witters, L. A., Parker, M. W., et al. (2003) · Current Biology
Metabolism, Diabetes, and CancerGlycogen Storage Diseases and Myoclonus
Cited by 423
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Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration
Moiseeva, V., Cisneros, A., Sica, V., Deryagin, O., Lai, Y., Jung, S., Andrés, E., An, J., Segalés, J., Ortet, L., et al. (2023) · Nature
Telomeres, Telomerase, and SenescenceMuscle Physiology and Disorders
Cited by 423
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Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth
Martinez-Outschoorn, U. E., Lisanti, M. P., & Sotgia, F. (2014) · Seminars in Cancer Biology
Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis
Cited by 423
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Mitotic Spindle Orientation in Asymmetric and Symmetric Cell Divisions during Animal Development
Morin, X., & Bellaïche, Y. (2011) · Developmental Cell
Microtubule and mitosis dynamicsDevelopmental Biology and Gene Regulation
Cited by 423
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