Most cited biochemistry, genetics and molecular biology papers
- Verified
The emergence of antibiotic resistance by mutation
Woodford, N., & Ellington, M. J. (2007) · Clinical Microbiology and Infection
Evolution and Genetic DynamicsAntibiotic Resistance in Bacteria
Cited by 417
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Computational tools for prioritizing candidate genes: boosting disease gene discovery
Moreau, Y., & Tranchevent, L.-C. (2012) · Nature Reviews Genetics
Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies
Cited by 417
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Recombinational DNA repair and human disease
Thompson, L. H., & Schild, D. (2002) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
DNA Repair MechanismsBRCA gene mutations in cancer
Cited by 417
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Peripheral-Type Benzodiazepine/Diazepam Binding Inhibitor Receptor: Biological Role in Steroidogenic Cell Function*
PAPADOPOULOS, V. (1993) · Endocrine Reviews
Estrogen and related hormone effectsReceptor Mechanisms and Signaling
Cited by 417
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Influence of Mediterranean Diet on Human Gut Microbiota
Merra, G., Noce, A., Marrone, G., Cintoni, M., Tarsitano, M. G., Capacci, A., & De Lorenzo, A. (2020) · Nutrients
Gut microbiota and healthNutritional Studies and Diet
Cited by 417
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The Skipping of Constitutive Exons in Vivo Induced by Nonsense Mutations
Dietz, H. C., Valle, D., Francomano, C. A., Kendzior, R. J., Pyeritz, R. E., & Cutting, G. A. (1993) · Science
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 417
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Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes.
Mali, P., Chou, B.-K., Yen, J., Ye, Z., Zou, J., Dowey, S., Brodsky, R. A., Ohm, J. E., Yu, W., Baylin, S. B., et al. (2010) · Stem Cells
Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation
Cited by 417
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Endogenous Nitric Oxide Protects Bacteria Against a Wide Spectrum of Antibiotics
Gusarov, I., Shatalin, K., Starodubtseva, M., & Nudler, E. (2009) · Science
Bacterial Genetics and BiotechnologyNitric Oxide and Endothelin Effects
Cited by 417
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Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells
Buchholz, D. E., Hikita, S. T., Rowland, T. J., Friedrich, A. M., Hinman, C. R., Johnson, L. V., & Clegg, D. O. (2009) · Stem Cells
Pluripotent Stem Cells ResearchRetinal Development and Disorders
Cited by 417
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Major phenylpropanoid‐derived metabolites in the human gut can arise from microbial fermentation of protein
Russell, W. R., Duncan, S. H., Scobbie, L., Duncan, G., Cantlay, L., Calder, A. G., Anderson, S. E., & Flint, H. J. (2013) · Molecular Nutrition & Food Research
Gut microbiota and healthPhytochemicals and Antioxidant Activities
Cited by 417
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Mesenchymal Stem Cell Delivery of TRAIL Can Eliminate Metastatic Cancer
Loebinger, M. R., Eddaoudi, A., Davies, D., & Janes, S. M. (2009) · Cancer Research
Mesenchymal stem cell researchBacterial Cancer Therapy
Cited by 417
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Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts
Guo, Z., Kumagai, A., Wang, S. X., & Dunphy, W. G. (2000) · Genes & Development
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 417
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The challenge and prospect of mRNA therapeutics landscape
Weng, Y., Li, C., Yang, T., Hu, B., Zhang, M., Guo, S., Xiao, H., Liang, X.-J., & Huang, Y. (2020) · Biotechnology Advances
RNA Interference and Gene DeliveryRNA and protein synthesis mechanisms
Cited by 417
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Spatial profiling of chromatin accessibility in mouse and human tissues
Deng, Y., Bartosovic, M., Ma, S., Zhang, D., Kukanja, P., Xiao, Y., Su, G., Liu, Y., Qin, X., Rosoklija, G. B., et al. (2022) · Nature
Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics
Cited by 417
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Muscle-specific PPARγ-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones
Norris, A. W., Chen, L., Fisher, S. J., Szanto, I., Ristow, M., Jozsi, A. C., Hirshman, M. F., Rosen, E. D., Goodyear, L. J., Gonzalez, F. J., et al. (2003) · Journal of Clinical Investigation
Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism
Cited by 417
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Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia
Woods, D. F., Hough, C., Peel, D., Callaini, G., & Bryant, P. J. (1996) · The Journal of cell biology
Developmental Biology and Gene RegulationHippo pathway signaling and YAP/TAZ
Cited by 417
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Phospholipids and the origin of cationic gating charges in voltage sensors
Schmidt, D., Jiang, Q.-X., & MacKinnon, R. (2006) · Nature
Ion channel regulation and functionLipid Membrane Structure and Behavior
Cited by 417
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UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor
Kopp, M. C., Larburu, N., Durairaj, V., Adams, C. J., & Ali, M. M. U. (2019) · Nature Structural & Molecular Biology
Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research
Cited by 417
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NRF-1: a trans-activator of nuclear-encoded respiratory genes in animal cells.
Evans, M. J., & Scarpulla, R. C. (1990) · Genes & Development
Mitochondrial Function and PathologyGenomics and Chromatin Dynamics
Cited by 417
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Cholesterol Addition to ER Membranes Alters Conformation of SCAP, the SREBP Escort Protein that Regulates Cholesterol Metabolism
Brown, A. J., Sun, L., Feramisco, J. D., Brown, M. S., & Goldstein, J. L. (2002) · Molecular Cell
Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism
Cited by 417
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Statins: a repurposed drug to fight cancer
Jiang, W., Hu, J.-W., He, X.-R., Jin, W.-L., & He, X.-Y. (2021) · Journal of Experimental & Clinical Cancer Research
Cancer, Lipids, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 417
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Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis
Lotta, L. A., Scott, R. A., Sharp, S. J., Burgess, S., Luan, J., Tillin, T., Schmidt, A. F., Imamura, F., Stewart, I. D., Perry, J. R. B., et al. (2016) · PLOS Medicine
Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins
Cited by 417
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Evolution of Gene Regulatory Networks Controlling Body Plan Development
Peter, I. S., & Davidson, E. H. (2011) · Cell
Developmental Biology and Gene RegulationGene Regulatory Network Analysis
Cited by 417
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Frequency and phenotype of type 1 diabetes in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank
Thomas, N. J., Jones, S. E., Weedon, M. N., Shields, B. M., Oram, R. A., & Hattersley, A. T. (2018) · The Lancet Diabetes & Endocrinology
Diabetes and associated disordersGenetic Associations and Epidemiology
Cited by 417
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