Most cited biochemistry, genetics and molecular biology papers
- Verified
Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice.
Tsujinaka, T., Fujita, J., Ebisui, C., Yano, M., Kominami, E., Suzuki, K., Tanaka, K., Katsume, A., Ohsugi, Y., Shiozaki, H., et al. (1996) · Journal of Clinical Investigation
Muscle Physiology and DisordersNutrition and Health in Aging
Cited by 421
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A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1
Wang, Y., An, R., Umanah, G. K., Park, H., Nambiar, K., Eacker, S. M., Kim, B., Bao, L., Harraz, M. M., Chang, C., et al. (2016) · Science
Cell death mechanisms and regulationMacrophage Migration Inhibitory Factor
Cited by 421
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A Perspective on the Maillard Reaction and the Analysis of Protein Glycation by Mass Spectrometry: Probing the Pathogenesis of Chronic Disease
Zhang, Q., Ames, J. M., Smith, R. D., Baynes, J. W., & Metz, T. O. (2009) · Journal of Proteome Research
Advanced Glycation End Products researchPotato Plant Research
Cited by 421
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Zif268 protein–DNA complex refined at 1.6å: a model system for understanding zinc finger–DNA interactions
Elrod-Erickson, M., Rould, M. A., Nekludova, L., & Pabo, C. O. (1996) · Structure
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 421
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Dali/FSSP classification of three-dimensional protein folds
Holm, L., & Sander, C. (1997) · Nucleic Acids Research
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 421
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A simple correction for multiple comparisons in interval mapping genome scans
Cheverud, J. M. (2001) · Heredity
Genetic Mapping and Diversity in Plants and AnimalsGenetic Associations and Epidemiology
Cited by 421
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The role of cholesterol in membrane fusion
Yang, S.-T., Kreutzberger, A. J. B., Lee, J., Kiessling, V., & Tamm, L. K. (2016) · Chemistry and Physics of Lipids
Lipid Membrane Structure and BehaviorCellular transport and secretion
Cited by 421
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Leukocyte Telomere Length in Major Depression: Correlations with Chronicity, Inflammation and Oxidative Stress - Preliminary Findings
Wolkowitz, O. M., Mellon, S. H., Epel, E. S., Lin, J., Dhabhar, F. S., Su, Y., Reus, V. I., Rosser, R., Burke, H. M., Kupferman, E., et al. (2011) · PLoS ONE
Telomeres, Telomerase, and SenescenceStress Responses and Cortisol
Cited by 421
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Dysregulated Metabotropic Glutamate Receptor-Dependent Translation of AMPA Receptor and Postsynaptic Density-95 mRNAs at Synapses in a Mouse Model of Fragile X Syndrome
Muddashetty, R. S., Kelić, S., Gross, C., Xu, M., & Bassell, G. J. (2007) · The Journal of Neuroscience
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 421
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Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling.
Koch, W. J., Hawes, B. E., Inglese, J., Luttrell, L. M., & Lefkowitz, R. J. (1994) · Journal of Biological Chemistry
Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling
Cited by 421
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Generation of induced pluripotent stem cells from urine
Zhou, T., Benda, C., Duzinger, S., Huang, Y., Li, X., Li, Y., Guo, X., Cao, G., Chen, S., Hao, L., et al. (2011) · Journal of the American Society of Nephrology
Pluripotent Stem Cells ResearchMesenchymal stem cell research
Cited by 421
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RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation
Lin, J., Kumari, S., Kim, C., Van, T.-M., Wachsmuth, L., Polykratis, A., & Pasparakis, M. (2016) · Nature
Cell death mechanisms and regulationImmune Response and Inflammation
Cited by 421
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Histone deacetylase inhibitors: Mechanisms of cell death and promise in combination cancer therapy
Carew, J. S., Giles, F. J., & Nawrocki, S. T. (2008) · Cancer Letters
Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation
Cited by 421
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A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions
Noel, G., Baetz, N. W., Staab, J. F., Donowitz, M., Kovbasnjuk, O., Pasetti, M. F., & Zachos, N. C. (2017) · Scientific Reports
Gut microbiota and healthEscherichia coli research studies
Cited by 420
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Kinase mutations in human disease: interpreting genotype–phenotype relationships
Lahiry, P., Torkamani, A., Schork, N. J., & Hegele, R. A. (2010) · Nature Reviews Genetics
Genomics and Rare DiseasesProtein Kinase Regulation and GTPase Signaling
Cited by 420
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Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice
Lee, T.-H. (2003) · Blood
Redox biology and oxidative stressErythrocyte Function and Pathophysiology
Cited by 420
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Insulated Neighborhoods: Structural and Functional Units of Mammalian Gene Control
Hnisz, D., Day, D. S., & Young, R. A. (2016) · Cell
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 420
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Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
Shadrin, I. Y., Allen, B. W., Qian, Y., Jackman, C. P., Carlson, A. L., Juhas, M. E., & Bursac, N. (2017) · Nature Communications
Pluripotent Stem Cells ResearchTissue Engineering and Regenerative Medicine
Cited by 420
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Microscopic analysis of polymerization dynamics with individual actin filaments
Fujiwara, I., Takahashi, S., Tadakuma, H., Funatsu, T., & Ishiwata, S. (2002) · Nature Cell Biology
Cellular Mechanics and InteractionsMicrotubule and mitosis dynamics
Cited by 420
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Interplay between miRNAs and human diseases
Paul, P., Chakraborty, A., Sarkar, D., Langthasa, M., Rahman, M., Bari, M., Singha, R. S., Malakar, A. K., & Chakraborty, S. (2018) · Journal of Cellular Physiology
MicroRNA in disease regulationCancer-related molecular mechanisms research
Cited by 420
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AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset
Goertsen, D., Flytzanis, N. C., Goeden, N., Chuapoco, M. R., Cummins, A., Chen, Y., Fan, Y., Zhang, Q., Sharma, J., Duan, Y., et al. (2022) · Nature Neuroscience
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 420
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RANK/RANKL: Regulators of Immune Responses and Bone Physiology
Leibbrandt, A., & Penninger, J. M. (2008) · Annals of the New York Academy of Sciences
Bone Metabolism and DiseasesRheumatoid Arthritis Research and Therapies
Cited by 420
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Function of Akkermansia muciniphila in obesity: interactions with lipid metabolism, immune response and gut systems
Xu, Y., Wang, N., Tan, H.-Y., Li, S., Zhang, C., & Feng, Y. (2020) · Frontiers in Microbiology
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 420
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mTOR , metabolism, and the regulation of T‐cell differentiation and function
Waickman, A. T., & Powell, J. D. (2012) · Immunological Reviews
PI3K/AKT/mTOR signaling in cancerT-cell and B-cell Immunology
Cited by 420
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