Most cited biochemistry, genetics and molecular biology papers
- Verified
Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer
Di Micco, R., Sulli, G., Dobreva, M., Liontos, M., Botrugno, O. A., Gargiulo, G., dal Zuffo, R., Matti, V., d'Ario, G., Montani, E., et al. (2011) · Nature Cell Biology
Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics
Cited by 382
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ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis
Ohno, Y., Suto, S., Yamanaka, M., Mizutani, Y., Mitsutake, S., Igarashi, Y., Sassa, T., & Kihara, A. (2010) · Proceedings of the National Academy of Sciences
Sphingolipid Metabolism and SignalingLipid metabolism and biosynthesis
Cited by 382
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Wnt/β-catenin signaling pathway in carcinogenesis and cancer therapy
Song, P., Gao, Z., Bao, Y., Chen, L., Huang, Y., Liu, Y., Dong, Q., & Wei, X. (2024) · Journal of Hematology & Oncology
Wnt/β-catenin signaling in development and cancerColorectal Cancer Treatments and Studies
Cited by 382
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ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A
Williamson, C. T., Miller, R., Pemberton, H. N., Jones, S. E., Campbell, J., Konde, A., Badham, N., Rafiq, R., Brough, R., Gulati, A., et al. (2016) · Nature Communications
Chromatin Remodeling and CancerDNA Repair Mechanisms
Cited by 382
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TGFB2 mutations cause familial thoracic aortic aneurysms and dissections associated with mild systemic features of Marfan syndrome
National Heart, L., Boileau, C., Guo, D.-C., Hanna, N., Regalado, E. S., Detaint, D., Gong, L., Varret, M., Prakash, S. K., Li, A. H., et al. (2012) · Nature Genetics
Connective tissue disorders researchAortic Disease and Treatment Approaches
Cited by 382
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Short chain fatty acids exchange across the gut and liver in humans measured at surgery
Bloemen, J. G., Venema, K., van de Poll, M. C., Olde Damink, S. W., Buurman, W. A., & Dejong, C. H. (2009) · Clinical Nutrition
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 382
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Golden Exosomes Selectively Target Brain Pathologies in Neurodegenerative and Neurodevelopmental Disorders
Perets, N., Betzer, O., Shapira, R., Brenstein, S., Angel, A., Sadan, T., Ashery, U., Popovtzer, R., & Offen, D. (2019) · Nano Letters
Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery
Cited by 382
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Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis
Rabinovich, S., Adler, L., Yizhak, K., Sarver, A., Silberman, A., Agron, S., Stettner, N., Sun, Q., Brandis, A., Helbling, D., et al. (2015) · Nature
Biochemical and Molecular ResearchAmino Acid Enzymes and Metabolism
Cited by 382
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von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF.
Hoffman, M. A. (2001) · Human Molecular Genetics
Cancer, Hypoxia, and MetabolismEar and Head Tumors
Cited by 382
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Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs
Todkar, K., Chikhi, L., Desjardins, V., El-Mortada, F., Pépin, G., & Germain, M. (2021) · Nature Communications
Extracellular vesicles in diseaseMitochondrial Function and Pathology
Cited by 382
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Genetic and Epigenetic Networks in Intellectual Disabilities
van Bokhoven, H. (2011) · Annual Review of Genetics
Genetics and Neurodevelopmental DisordersDown syndrome and intellectual disability research
Cited by 382
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Discodermolide, A Cytotoxic Marine Agent That Stabilizes Microtubules More Potently Than Taxol,
ter Haar, E., Kowalski, R. J., Hamel, E., Lin, C. M., Longley, R. E., Gunasekera, S. P., Rosenkranz, H. S., & Day, B. W. (1996) · Biochemistry
Microtubule and mitosis dynamicsCancer Treatment and Pharmacology
Cited by 382
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A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing
Zhao, Y., Lang, G., Ito, S., Bonnet, J., Metzger, E., Sawatsubashi, S., Suzuki, E., Le Guezennec, X., Stunnenberg, H. G., Krasnov, A., et al. (2008) · Molecular Cell
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 382
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Antibiotic Treatment Alters the Colonic Mucus Layer and Predisposes the Host to Exacerbated Citrobacter rodentium -Induced Colitis
Wlodarska, M., Willing, B., Keeney, K. M., Menendez, A., Bergstrom, K. S., Gill, N., Russell, S. L., Vallance, B. A., & Finlay, B. B. (2011) · Infection and Immunity
Gut microbiota and healthEscherichia coli research studies
Cited by 382
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Compartmentalized and systemic control of tissue immunity by commensals
Belkaid, Y., & Naik, S. (2013) · Nature Immunology
Gut microbiota and healthT-cell and B-cell Immunology
Cited by 382
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Rheb Activates mTOR by Antagonizing Its Endogenous Inhibitor, FKBP38
Bai, X., Ma, D., Liu, A., Shen, X., Wang, Q. J., Liu, Y., & Jiang, Y. (2007) · Science
PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling
Cited by 382
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DNA adducts from acetaldehyde: implications for alcohol-related carcinogenesis
Brooks, P. J., & Theruvathu, J. A. (2005) · Alcohol
Carcinogens and Genotoxicity AssessmentDNA Repair Mechanisms
Cited by 382
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LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes
Zhou, C., Yi, C., Yi, Y., Qin, W., Yan, Y., Dong, X., Zhang, X., Huang, Y., Zhang, R., Wei, J., et al. (2020) · Molecular Cancer
Cancer-related molecular mechanisms researchMicroRNA in disease regulation
Cited by 382
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Controlling cholesterol synthesis beyond 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)
Sharpe, L. J., & Brown, A. J. (2013) · Journal of Biological Chemistry
Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism
Cited by 382
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DNA methylation signatures in peripheral blood strongly predict all-cause mortality
Zhang, Y., Wilson, R., Heiss, J., Breitling, L. P., Saum, K.-U., Schöttker, B., Holleczek, B., Waldenberger, M., Peters, A., & Brenner, H. (2017) · Nature Communications
Epigenetics and DNA MethylationGenetic Associations and Epidemiology
Cited by 382
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Insulin signaling and insulin sensitivity after exercise in human skeletal muscle
Wojtaszewski, J. F., Hansen, B. F., Gade, Kiens, B., Markuns, J. F., Goodyear, L. J., & Richter, E. A. (2000) · Diabetes
Metabolism, Diabetes, and CancerMuscle metabolism and nutrition
Cited by 382
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RXRα Inhibits the NRF2-ARE Signaling Pathway through a Direct Interaction with the Neh7 Domain of NRF2
Wang, H., Liu, K., Geng, M., Gao, P., Wu, X., Hai, Y., Li, Y., Li, Y., Luo, L., Hayes, J. D., et al. (2013) · Cancer Research
Genomics, phytochemicals, and oxidative stressGlutathione Transferases and Polymorphisms
Cited by 382
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Role of triglyceride-fatty acid cycle in controlling fat metabolism in humans during and after exercise
Wolfe, R. R., Klein, S., Carraro, F., & Weber, J. M. (1990) · American Journal of Physiology-Endocrinology and Metabolism
Lipid metabolism and biosynthesisMuscle metabolism and nutrition
Cited by 381
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Genetic and environmental control of host-gut microbiota interactions
Org, E., Parks, B. W., Joo, J. W. J., Emert, B., Schwartzman, W., Kang, E. Y., Mehrabian, M., Pan, C., Knight, R., Gunsalus, R., et al. (2015) · Genome Research
Gut microbiota and healthNutrition, Genetics, and Disease
Cited by 381
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