Most cited biochemistry, genetics and molecular biology papers
- Verified
The RAGE axis: A fundamental mechanism signaling danger to the vulnerable vasculature
Yan, S. F., Ramasamy, R., & Schmidt, A. M. (2010) · Circulation Research
Advanced Glycation End Products researchAldose Reductase and Taurine
Cited by 381
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Innovations present in the primate interneuron repertoire
Krienen, F. M., Goldman, M., Zhang, Q., C. H. del Rosario, R., Florio, M., Machold, R., Saunders, A., Levandowski, K., Zaniewski, H., Schuman, B., et al. (2020) · Nature
Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research
Cited by 381
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Evaluation of methods for modeling transcription factor sequence specificity
DREAM5 Consortium, Weirauch, M. T., Cote, A., Norel, R., Annala, M., Zhao, Y., Riley, T. R., Saez-Rodriguez, J., Cokelaer, T., Vedenko, A., et al. (2013) · Nature Biotechnology
Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies
Cited by 381
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SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling
Toiber, D., Erdel, F., Bouazoune, K., Silberman, D. M., Zhong, L., Mulligan, P., Sebastian, C., Cosentino, C., Martinez-Pastor, B., Giacosa, S., et al. (2013) · Molecular Cell
DNA Repair MechanismsSirtuins and Resveratrol in Medicine
Cited by 381
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Tumor-associated macrophages-derived exosomes promote the migration of gastric cancer cells by transfer of functional Apolipoprotein E
Zheng, P., Luo, Q., Wang, W., Li, J., Wang, T., Wang, P., Chen, L., Zhang, P., Chen, H., Liu, Y., et al. (2018) · Cell Death & Disease
Extracellular vesicles in diseaseImmune cells in cancer
Cited by 381
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Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy
Risson, V., Mazelin, L., Roceri, M., Sanchez, H., Moncollin, V., Corneloup, C., Richard-Bulteau, H., Vignaud, A., Baas, D., Defour, A., et al. (2009) · Journal of Cell Biology
Muscle Physiology and DisordersPI3K/AKT/mTOR signaling in cancer
Cited by 381
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Nebulosa recovers single-cell gene expression signals by kernel density estimation
Alquicira-Hernandez, J., & Powell, J. E. (2021) · Bioinformatics
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 381
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Cell death by autophagy: facts and apparent artefacts
Denton, D., Nicolson, S., & Kumar, S. (2012) · Cell Death & Differentiation
Autophagy in Disease and TherapyCell death mechanisms and regulation
Cited by 381
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Mitochondrial Networking Protects β-Cells From Nutrient-Induced Apoptosis
Molina, A. J. A., Wikstrom, J. D., Stiles, L., Las, G., Mohamed, H., Elorza, A., Walzer, G., Twig, G., Katz, S., Corkey, B. E., et al. (2009) · Diabetes
Mitochondrial Function and PathologyPancreatic function and diabetes
Cited by 381
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Mammalian cell cycle checkpoints: signalling pathways and their organization in space and time
Lukas, J., Lukas, C., & Bartek, J. (2004) · DNA Repair
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 381
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Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors
Murga, M., Campaner, S., Lopez-Contreras, A. J., Toledo, L. I., Soria, R., Montaña, M. F., D'Artista, L., Schleker, T., Guerra, C., Garcia, E., et al. (2011) · Nature Structural & Molecular Biology
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 381
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Phenotype plasticity as enabler of melanoma progression and therapy resistance
Arozarena, I., & Wellbrock, C. (2019) · Nature Reviews Cancer
Melanoma and MAPK PathwaysCancer Cells and Metastasis
Cited by 381
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Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells
Young, S. D., Marshall, R. S., & Hill, R. P. (1988) · Proceedings of the National Academy of Sciences
Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis
Cited by 381
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A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice
Tian, Y., Liu, Y., Wang, T., Zhou, N., Kong, J., Chen, L., Snitow, M., Morley, M., Li, D., Petrenko, N., et al. (2015) · Science Translational Medicine
Congenital heart defects researchNeurogenesis and neuroplasticity mechanisms
Cited by 381
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The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos
Park, M., & Moon, R. T. (2002) · Nature Cell Biology
Developmental Biology and Gene RegulationWnt/β-catenin signaling in development and cancer
Cited by 381
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Diagnosis, natural history, and management in vascular Ehlers-Danlos syndrome
Byers, P. H., Belmont, J., Black, J., De Backer, J., Frank, M., Jeunemaitre, X., Johnson, D., Pepin, M., Robert, L., Sanders, L., et al. (2017) · American Journal of Medical Genetics Part C: Seminars in Medical Genetics
Connective tissue disorders researchDermatological and Skeletal Disorders
Cited by 381
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Proteolysis of the Hedgehog Signaling Effector Cubitus interruptus Requires Phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1
Price, M. A., & Kalderon, D. (2002) · Cell
Hedgehog Signaling Pathway StudiesWnt/β-catenin signaling in development and cancer
Cited by 381
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Structural changes in the gut microbiome of constipated patients
Zhu, L., Liu, W., Alkhouri, R., Baker, R. D., Bard, J. E., Quigley, E. M., & Baker, S. S. (2014) · Physiological Genomics
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 381
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Detection of regulatory variation in mouse genes
Cowles, C. R., Hirschhorn, J. N., Altshuler, D., & Lander, E. S. (2002) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 381
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Machine learning and integrative analysis of biomedical big data
Mirza, B., Wang, W., Wang, J., Choi, H., Chung, N. C., & Ping, P. (2019) · Genes
Bioinformatics and Genomic NetworksGene expression and cancer classification
Cited by 380
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High-throughput RNAi screening in cultured cells: a user's guide
Echeverri, C. J., & Perrimon, N. (2006) · Nature Reviews Genetics
RNA Interference and Gene DeliveryCRISPR and Genetic Engineering
Cited by 380
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A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies
Lehne, B., Drong, A. W., Loh, M., Zhang, W., Scott, W. R., Tan, S.-T., Afzal, U., Scott, J., Jarvelin, M.-R., Elliott, P., et al. (2015) · Genome biology
Epigenetics and DNA MethylationGenetic Associations and Epidemiology
Cited by 380
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Identification of a heparin-binding motif on adeno-associated virus type 2 capsids
Kern, A., Schmidt, K., Leder, C., Müller, O. J., Wobus, C. E., Bettinger, K., Von der Lieth, C. W., King, J. A., & Kleinschmidt, J. A. (2003) · Journal of Virology
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 380
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Mechanisms of transcription-coupled DNA repair
Svejstrup, J. Q. (2002) · Nature Reviews Molecular Cell Biology
DNA Repair MechanismsGenomics and Chromatin Dynamics
Cited by 380
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