Most cited biochemistry, genetics and molecular biology papers
- Verified
Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences
The 1000 Genomes Project Consortium, Poznik, G. D., Xue, Y., Mendez, F. L., Willems, T. F., Massaia, A., Wilson Sayres, M. A., Ayub, Q., McCarthy, S. A., Narechania, A., et al. (2016) · Nature Genetics
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 331
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A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity
Inoue, F., Kircher, M., Martin, B., Cooper, G. M., Witten, D. M., McManus, M. T., Ahituv, N., & Shendure, J. (2017) · Genome Research
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 331
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Gain Modulation by Nicotine in Macaque V1
Disney, A. A., Aoki, C., & Hawken, M. J. (2007) · Neuron
Nicotinic Acetylcholine Receptors StudyVisual perception and processing mechanisms
Cited by 331
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Genomic Ancestry of North Africans Supports Back-to-Africa Migrations
Henn, B. M., Botigué, L. R., Gravel, S., Wang, W., Brisbin, A., Byrnes, J. K., Fadhlaoui-Zid, K., Zalloua, P. A., Moreno-Estrada, A., Bertranpetit, J., et al. (2012) · PLoS Genetics
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 331
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Optimized CRISPR guide RNA design for two high-fidelity Cas9 variants by deep learning
Wang, D., Zhang, C., Wang, B., Li, B., Wang, Q., Liu, D., Wang, H., Zhou, Y., Shi, L., Lan, F., et al. (2019) · Nature Communications
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 331
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Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial
Canfora, E. E., van der Beek, C. M., Jocken, J. W. E., Goossens, G. H., Holst, J. J., Olde Damink, S. W. M., Lenaerts, K., Dejong, C. H. C., & Blaak, E. E. (2017) · Scientific Reports
Gut microbiota and healthRegulation of Appetite and Obesity
Cited by 331
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Stable Histone Deacetylase Complexes Distinguished by the Presence of SANT Domain Proteins CoREST/kiaa0071 and Mta-L1
Humphrey, G. W., Wang, Y., Russanova, V. R., Hirai, T., Qin, J., Nakatani, Y., & Howard, B. H. (2001) · Journal of Biological Chemistry
Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics
Cited by 331
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Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration
Menon, M., Mohammadi, S., Davila-Velderrain, J., Goods, B. A., Cadwell, T. D., Xing, Y., Stemmer-Rachamimov, A., Shalek, A. K., Love, J. C., Kellis, M., et al. (2019) · Nature Communications
Single-cell and spatial transcriptomicsRetinal Development and Disorders
Cited by 331
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The metabolic fate of acetate in cancer
Schug, Z. T., Vande Voorde, J., & Gottlieb, E. (2016) · Nature reviews. Cancer
Cancer, Lipids, and MetabolismCancer, Hypoxia, and Metabolism
Cited by 331
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Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression
Cuomo, A. S. E., Seaton, D. D., McCarthy, D. J., Martinez, I., Bonder, M. J., Garcia-Bernardo, J., Amatya, S., Madrigal, P., Isaacson, A., Buettner, F., et al. (2020) · Nature Communications
Pluripotent Stem Cells ResearchSingle-cell and spatial transcriptomics
Cited by 331
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The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain
Gehman, L. T., Stoilov, P., Maguire, J., Damianov, A., Lin, C.-H., Shiue, L., Ares, M., Mody, I., & Black, D. L. (2011) · Nature Genetics
RNA Research and SplicingEpilepsy research and treatment
Cited by 331
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TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages
Pastore, N., Brady, O. A., Diab, H. I., Martina, J. A., Sun, L., Huynh, T., Lim, J.-A., Zare, H., Raben, N., Ballabio, A., et al. (2016) · Autophagy
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 331
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FoxO Transcription Factors and Stem Cell Homeostasis: Insights from the Hematopoietic System
Tothova, Z., & Gilliland, D. G. (2007) · Cell Stem Cell
FOXO transcription factor regulationHematopoietic Stem Cell Transplantation
Cited by 331
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Autophagy in cardiovascular biology
Lavandero, S., Chiong, M., Rothermel, B. A., & Hill, J. A. (2015) · Journal of Clinical Investigation
Autophagy in Disease and TherapyCardiac Fibrosis and Remodeling
Cited by 331
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GABAA Receptor Promoter Hypermethylation in Suicide Brain: Implications for the Involvement of Epigenetic Processes
Poulter, M. O., Du, L., Weaver, I. C. G., Palkovits, M., Faludi, G., Merali, Z., Szyf, M., & Anisman, H. (2008) · Biological Psychiatry
Epigenetics and DNA MethylationSuicide and Self-Harm Studies
Cited by 331
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AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress
Nagata, D., Mogi, M., & Walsh, K. (2003) · Journal of Biological Chemistry
Angiogenesis and VEGF in CancerMetabolism, Diabetes, and Cancer
Cited by 331
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Protein acetylation in metabolism – metabolites and cofactors
Menzies, K. J., Zhang, H., Katsyuba, E., & Auwerx, J. (2016) · Nature Reviews Endocrinology
Histone Deacetylase Inhibitors ResearchSirtuins and Resveratrol in Medicine
Cited by 331
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Morpheus Unbound: Reimagining the Morphogen Gradient
Lander, A. D. (2007) · Cell
Developmental Biology and Gene RegulationWnt/β-catenin signaling in development and cancer
Cited by 331
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Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors
Davidson, S. M., Jonas, O., Keibler, M. A., Hou, H. W., Luengo, A., Mayers, J. R., Wyckoff, J., Del Rosario, A. M., Whitman, M., Chin, C. R., et al. (2017) · Nature Medicine
Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism
Cited by 331
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Lyophilization provides long-term stability for a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine
Muramatsu, H., Lam, K., Bajusz, C., Laczkó, D., Karikó, K., Schreiner, P., Martin, A., Lutwyche, P., Heyes, J., & Pardi, N. (2022) · Molecular Therapy
RNA Interference and Gene DeliverySARS-CoV-2 and COVID-19 Research
Cited by 331
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Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells
Ram, O., Goren, A., Amit, I., Shoresh, N., Yosef, N., Ernst, J., Kellis, M., Gymrek, M., Issner, R., Coyne, M., et al. (2011) · Cell
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 331
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Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice
Yousefzadeh, M. J., Zhao, J., Bukata, C., Wade, E. A., McGowan, S. J., Angelini, L. A., Bank, M. P., Gurkar, A. U., McGuckian, C. A., Calubag, M. F., et al. (2020) · Aging Cell
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 331
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Infant antibiotic exposure and the development of childhood overweight and central adiposity
Azad, M. B., Bridgman, S. L., Becker, A. B., & Kozyrskyj, A. L. (2014) · International Journal of Obesity
Gut microbiota and healthObesity, Physical Activity, Diet
Cited by 331
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Effect of limb immobilization on skeletal muscle
Booth, F. W. (1982) · Journal of Applied Physiology
Muscle Physiology and DisordersSpaceflight effects on biology
Cited by 331
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