Most cited biochemistry, genetics and molecular biology papers
- Verified
Genome-wide assessment of worldwide chicken SNP genetic diversity indicates significant absence of rare alleles in commercial breeds
Muir, W. M., Wong, G. K.-S., Zhang, Y., Wang, J., Groenen, M. A. M., Crooijmans, R. P. M. A., Megens, H.-J., Zhang, H., Okimoto, R., Vereijken, A., et al. (2008) · Proceedings of the National Academy of Sciences
Genetic and phenotypic traits in livestockLivestock and Poultry Management
Cited by 319
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A “metastasis-prone” signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics
Hong, Y., Downey, T., Eu, K. W., Koh, P. K., & Cheah, P. Y. (2010) · Clinical & Experimental Metastasis
Gene expression and cancer classificationColorectal Cancer Treatments and Studies
Cited by 319
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Regulation of the epigenome by vitamin C
Young, J. I., Züchner, S., & Wang, G. (2015) · Annual Review of Nutrition
Epigenetics and DNA MethylationVitamin C and Antioxidants Research
Cited by 319
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Use of Confocal Microscopy To Analyze the Rate of Vancomycin Penetration through Staphylococcus aureus Biofilms
Jefferson, K. K., Goldmann, D. A., & Pier, G. B. (2005) · Antimicrobial Agents and Chemotherapy
Bacterial biofilms and quorum sensingAntimicrobial Resistance in Staphylococcus
Cited by 319
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Insights into the mechanism of microtubule stabilization by Taxol
Xiao, H., Verdier-Pinard, P., Fernandez-Fuentes, N., Burd, B., Angeletti, R., Fiser, A., Horwitz, S. B., & Orr, G. A. (2006) · Proceedings of the National Academy of Sciences
Microtubule and mitosis dynamicsCancer Treatment and Pharmacology
Cited by 319
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Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist
Ahuja, S., Mukund, S., Deng, L., Khakh, K., Chang, E., Ho, H., Shriver, S., Young, C., Lin, S., Johnson, J. P., et al. (2015) · Science
Ion channel regulation and functionCardiac electrophysiology and arrhythmias
Cited by 319
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Ultrahigh resolution drug design I: Details of interactions in human aldose reductase–inhibitor complex at 0.66 Å
Howard, E. I., Sanishvili, R., Cachau, R. E., Mitschler, A., Chevrier, B., Barth, P., Lamour, V., Van Zandt, M., Sibley, E., Bon, C., et al. (2004) · Proteins: Structure, Function, and Bioinformatics
Aldose Reductase and TaurineEnzyme Structure and Function
Cited by 319
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Commensal bacteria, traditional and opportunistic pathogens, dysbiosis and bacterial killing in inflammatory bowel diseases
Packey, C. D., & Sartor, R. B. (2009) · Current Opinion in Infectious Diseases
Gut microbiota and healthInflammatory Bowel Disease
Cited by 319
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Tall fescue EST-SSR markers with transferability across several grass species
Saha, M. C., Mian, M. A. R., Eujayl, I., Zwonitzer, J. C., Wang, L., & May, G. D. (2004) · Theoretical and Applied Genetics
Genetic Mapping and Diversity in Plants and AnimalsChromosomal and Genetic Variations
Cited by 319
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DNA Damage-Induced Acetylation of Lysine 3016 of ATM Activates ATM Kinase Activity
Sun, Y., Xu, Y., Roy, K., & Price, B. D. (2007) · Molecular and Cellular Biology
DNA Repair MechanismsGenomics and Chromatin Dynamics
Cited by 319
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Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action
Eldar-Finkelman, H., & Krebs, E. G. (1997) · Proceedings of the National Academy of Sciences
Metabolism, Diabetes, and CancerProtein Kinase Regulation and GTPase Signaling
Cited by 319
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ISPAD Clinical Practice Consensus Guidelines 2018: The diagnosis and management of monogenic diabetes in children and adolescents
Hattersley, A. T., Greeley, S. A. W., Polak, M., Rubio-Cabezas, O., Njølstad, P. R., Mlynarski, W., Castano, L., Carlsson, A., Raile, K., Chi, D. V., et al. (2018) · Pediatric Diabetes
Diabetes and associated disordersDiabetes Management and Research
Cited by 319
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Mutations in TCF4, Encoding a Class I Basic Helix-Loop-Helix Transcription Factor, Are Responsible for Pitt-Hopkins Syndrome, a Severe Epileptic Encephalopathy Associated with Autonomic Dysfunction
Amiel, J., Rio, M., Pontual, L. D., Redon, R., Malan, V., Boddaert, N., Plouin, P., Carter, N. P., Lyonnet, S., Munnich, A., et al. (2007) · The American Journal of Human Genetics
Genetics and Neurodevelopmental DisordersEpilepsy research and treatment
Cited by 319
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Small Ubiquitin-like Modifier (SUMO) Modification of Natively Unfolded Proteins Tau and α-Synuclein
Dorval, V., & Fraser, P. E. (2006) · Journal of Biological Chemistry
Ubiquitin and proteasome pathwaysAlzheimer's disease research and treatments
Cited by 319
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Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions
Grubert, F., Zaugg, J. B., Kasowski, M., Ursu, O., Spacek, D. V., Martin, A. R., Greenside, P., Srivas, R., Phanstiel, D. H., Pekowska, A., et al. (2015) · Cell
Genomics and Chromatin DynamicsGenetic Associations and Epidemiology
Cited by 319
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CONVERSION OF ANDROSTENEDIONE TO ESTRONE BY HUMAN FAT TISSUE
Schindler, A. E., Ebert, A., & Friedrich, E. (1972) · The Journal of Clinical Endocrinology & Metabolism
Estrogen and related hormone effectsSteroid Chemistry and Biochemistry
Cited by 319
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Molecular mechanisms of UV-induced apoptosis
Kulms, D., & Schwarz, T. (2000) · Photodermatology, Photoimmunology & Photomedicine
Cell death mechanisms and regulationSkin Protection and Aging
Cited by 319
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Mechanism and inhibition of cytochrome P-450 aromatase
Cole, P. A., & Robinson, C. H. (1990) · Journal of Medicinal Chemistry
Estrogen and related hormone effectsMetal-Catalyzed Oxygenation Mechanisms
Cited by 319
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Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan
Muro, A. F., Chauhan, A. K., Gajovic, S., Iaconcig, A., Porro, F., Stanta, G., & Baralle, F. E. (2003) · The Journal of Cell Biology
RNA Research and SplicingCell Adhesion Molecules Research
Cited by 319
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Combinatorial metabolic engineering using an orthogonal tri-functional CRISPR system
Lian, J., HamediRad, M., Hu, S., & Zhao, H. (2017) · Nature Communications
Microbial Metabolic Engineering and BioproductionCRISPR and Genetic Engineering
Cited by 319
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A conserved family of elav-like genes in vertebrates.
Good, P. J. (1995) · Proceedings of the National Academy of Sciences
RNA Research and SplicingDevelopmental Biology and Gene Regulation
Cited by 319
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Suboptimization of developmental enhancers
Farley, E. K., Olson, K. M., Zhang, W., Brandt, A. J., Rokhsar, D. S., & Levine, M. S. (2015) · Science
Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation
Cited by 319
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Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition
Faber, A. C., Li, D., Song, Y., Liang, M.-C., Yeap, B. Y., Bronson, R. T., Lifshits, E., Chen, Z., Maira, S.-M., García-Echeverría, C., et al. (2009) · Proceedings of the National Academy of Sciences
PI3K/AKT/mTOR signaling in cancerLung Cancer Treatments and Mutations
Cited by 319
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Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance
Lee, H.-Y., Choi, C. S., Birkenfeld, A. L., Alves, T. C., Jornayvaz, F. R., Jurczak, M. J., Zhang, D., Woo, D. K., Shadel, G. S., Ladiges, W., et al. (2010) · Cell Metabolism
Mitochondrial Function and PathologyAdipose Tissue and Metabolism
Cited by 319
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