Most cited biochemistry, genetics and molecular biology papers
- Verified
Short-chain fatty acids (SCFAs) alone or in combination regulate select immune functions of microglia-like cells
Wenzel, T. J., Gates, E. J., Ranger, A. L., & Klegeris, A. (2020) · Molecular and Cellular Neuroscience
Gut microbiota and healthNeuroinflammation and Neurodegeneration Mechanisms
Cited by 320
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Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes
Naito, A. T., Sumida, T., Nomura, S., Liu, M.-L., Higo, T., Nakagawa, A., Okada, K., Sakai, T., Hashimoto, A., Hara, Y., et al. (2012) · Cell
Wnt/β-catenin signaling in development and cancerGenetics, Aging, and Longevity in Model Organisms
Cited by 320
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CRISPR Ethics: Moral Considerations for Applications of a Powerful Tool
Brokowski, C., & Adli, M. (2019) · Journal of Molecular Biology
CRISPR and Genetic EngineeringBiomedical Ethics and Regulation
Cited by 320
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Positive Darwinian evolution in human influenza A viruses.
Fitch, W. M., Leiter, J. M., Li, X. Q., & Palese, P. (1991) · Proceedings of the National Academy of Sciences
Evolution and Genetic DynamicsInfluenza Virus Research Studies
Cited by 320
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Interferon gamma-activated human monocytes downregulate transferrin receptors and inhibit the intracellular multiplication of Legionella pneumophila by limiting the availability of iron.
Byrd, T. F., & Horwitz, M. A. (1989) · Journal of Clinical Investigation
Legionella and Acanthamoeba researchIron Metabolism and Disorders
Cited by 320
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Role of glutamine and interlinked asparagine metabolism in vessel formation
Huang, H., Vandekeere, S., Kalucka, J., Bierhansl, L., Zecchin, A., Brüning, U., Visnagri, A., Yuldasheva, N., Goveia, J., Cruys, B., et al. (2017) · The EMBO Journal
Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism
Cited by 320
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Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection
Ye, L., Wang, J., Beyer, A. I., Teque, F., Cradick, T. J., Qi, Z., Chang, J. C., Bao, G., Muench, M. O., Yu, J., et al. (2014) · Proceedings of the National Academy of Sciences
CRISPR and Genetic EngineeringHIV Research and Treatment
Cited by 320
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Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry
Wang, Z., Levison, B. S., Hazen, J. E., Donahue, L., Li, X.-M., & Hazen, S. L. (2014) · Analytical Biochemistry
Metabolomics and Mass Spectrometry StudiesMetabolism and Genetic Disorders
Cited by 320
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Shared molecular and cellular mechanisms of premature ageing and ageing-associated diseases
Kubben, N., & Misteli, T. (2017) · Nature Reviews Molecular Cell Biology
Genetics, Aging, and Longevity in Model OrganismsNuclear Structure and Function
Cited by 320
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A Review on the Mechanism and Applications of CRISPR/Cas9/Cas12/Cas13/Cas14 Proteins Utilized for Genome Engineering
Hillary, V. E., & Ceasar, S. A. (2023) · Molecular Biotechnology
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 320
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Mechanisms that Regulate Stem Cell Aging and Life Span
Signer, R. A. J., & Morrison, S. J. (2013) · Cell Stem Cell
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 320
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Unraveling the Potential Role of Glutathione in Multiple Forms of Cell Death in Cancer Therapy
Lv, H., Zhen, C., Liu, J., Yang, P., Hu, L., & Shang, P. (2019) · Oxidative Medicine and Cellular Longevity
Sulfur Compounds in BiologyRedox biology and oxidative stress
Cited by 320
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H2AX: functional roles and potential applications
Dickey, J. S., Redon, C. E., Nakamura, A. J., Baird, B. J., Sedelnikova, O. A., & Bonner, W. M. (2009) · Chromosoma
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 320
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COL4A1 and COL4A2 mutations and disease: insights into pathogenic mechanisms and potential therapeutic targets
Kuo, D. S., Labelle-Dumais, C., & Gould, D. B. (2012) · Human Molecular Genetics
Connective tissue disorders researchCerebrovascular and genetic disorders
Cited by 320
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Human Mitochondrial Glutaredoxin Reduces S-Glutathionylated Proteins with High Affinity Accepting Electrons from Either Glutathione or Thioredoxin Reductase
Johansson, C., Lillig, C. H., & Holmgren, A. (2004) · Journal of Biological Chemistry
Redox biology and oxidative stressGlutathione Transferases and Polymorphisms
Cited by 320
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A Population of Myogenic Stem Cells That Survives Skeletal Muscle Aging
Collins, C. A., Zammit, P. S., Ruiz, A. P., Morgan, J. E., & Partridge, T. A. (2007) · Stem Cells
Muscle Physiology and DisordersMesenchymal stem cell research
Cited by 320
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Detection and quantification of mitochondrial DNA deletions in individual cells by real-time PCR
He, L. (2002) · Nucleic Acids Research
Mitochondrial Function and PathologyForensic and Genetic Research
Cited by 320
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Long-term regional suppression of pink bollworm by Bacillus thuringiensis cotton
Carrière, Y., Ellers-Kirk, C., Sisterson, M., Antilla, L., Whitlow, M., Dennehy, T. J., & Tabashnik, B. E. (2003) · Proceedings of the National Academy of Sciences
Insect Resistance and GeneticsGenetically Modified Organisms Research
Cited by 320
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A modular platform for targeted RNAi therapeutics
Kedmi, R., Veiga, N., Ramishetti, S., Goldsmith, M., Rosenblum, D., Dammes, N., Hazan-Halevy, I., Nahary, L., Leviatan-Ben-Arye, S., Harlev, M., et al. (2018) · Nature Nanotechnology
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 320
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Ubiquitous L1 Mosaicism in Hippocampal Neurons
Upton, K. R., Gerhardt, D. J., Jesuadian, J. S., Richardson, S. R., Sánchez-Luque, F. J., Bodea, G. O., Ewing, A. D., Salvador-Palomeque, C., van der Knaap, M. S., Brennan, P. M., et al. (2015) · Cell
Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities
Cited by 320
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Protein design and variant prediction using autoregressive generative models
Shin, J.-E., Riesselman, A. J., Kollasch, A. W., McMahon, C., Simon, E., Sander, C., Manglik, A., Kruse, A. C., & Marks, D. S. (2021) · Nature Communications
Protein Structure and DynamicsMachine Learning in Bioinformatics
Cited by 320
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Okihiro syndrome is caused by SALL4 mutations
Kohlhase, J. (2002) · Human Molecular Genetics
Congenital limb and hand anomaliesGenomics and Rare Diseases
Cited by 320
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Restriction of Advanced Glycation End Products Improves Insulin Resistance in Human Type 2 Diabetes
Uribarri, J., Cai, W., Ramdas, M., Goodman, S., Pyzik, R., Chen, X., Zhu, L., Striker, G. E., & Vlassara, H. (2011) · Diabetes Care
Advanced Glycation End Products researchAdipokines, Inflammation, and Metabolic Diseases
Cited by 320
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BMP restricts stemness of intestinal Lgr5(+) stem cells by directly suppressing their signature genes
Qi, Z., Li, Y., Zhao, B., Xu, C., Liu, Y., Li, H., Zhang, B., Wang, X., Yang, X., Xie, W., et al. (2017) · Nature Communications
TGF-β signaling in diseasesWnt/β-catenin signaling in development and cancer
Cited by 320
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