Most cited biochemistry, genetics and molecular biology papers
- Verified
PRAK Is Essential for ras-Induced Senescence and Tumor Suppression
Sun, P., Yoshizuka, N., New, L., Moser, B. A., Li, Y., Liao, R., Xie, C., Chen, J., Deng, Q., Yamout, M., et al. (2007) · Cell
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 321
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Circulating tumour DNA — looking beyond the blood
Tivey, A., Church, M., Rothwell, D., Dive, C., & Cook, N. (2022) · Nature Reviews Clinical Oncology
Cancer Genomics and DiagnosticsPrenatal Screening and Diagnostics
Cited by 321
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p53 and DNA damage-inducible expression of the xeroderma pigmentosum group C gene
Adimoolam, S., & Ford, J. M. (2002) · Proceedings of the National Academy of Sciences
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 321
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Insulin and IGF-1 stimulate the β-catenin pathway through two signalling cascades involving GSK-3β inhibition and Ras activation
Desbois-Mouthon, C., Cadoret, A., Blivet-Van Eggelpoël, M.-J., Bertrand, F., Cherqui, G., Perret, C., & Capeau, J. (2001) · Oncogene
Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease
Cited by 321
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Forward genetic analysis of visual behavior in zebrafish
Muto, A., Orger, M. B., Wehman, A. M., Smear, M. C., Kay, J. N., Page-McCaw, P. S., Gahtan, E., Xiao, T., Nevin, L. M., Gosse, N. J., et al. (2005) · PLoS Genetics
Zebrafish Biomedical Research ApplicationsRetinal Development and Disorders
Cited by 321
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Novel de novo SHANK3 mutation in autistic patients
Gauthier, J., Spiegelman, D., Piton, A., Lafrenière, R. G., Laurent, S., St‐Onge, J., Lapointe, L., Hamdan, F. F., Cossette, P., Mottron, L., et al. (2009) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 321
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Skin Senescence: Mechanisms and Impact on Whole-Body Aging
Franco, A. C., Aveleira, C., & Cavadas, C. (2022) · Trends in Molecular Medicine
Telomeres, Telomerase, and SenescenceSkin Protection and Aging
Cited by 321
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Epithelial-Mesenchymal Interactions in the Developing Lung
Shannon, J. M., & Hyatt, B. A. (2004) · Annual Review of Physiology
Developmental Biology and Gene RegulationNeonatal Respiratory Health Research
Cited by 321
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Delayed Stabilization of Dendritic Spines in Fragile X Mice
Cruz-Martin, A., Crespo, M., & Portera-Cailliau, C. (2010) · Journal of Neuroscience
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 321
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The triumphs and limitations of computational methods for scRNA-seq
Kharchenko, P. V. (2021) · Nature Methods
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 321
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The Vici Syndrome Protein EPG5 Is a Rab7 Effector that Determines the Fusion Specificity of Autophagosomes with Late Endosomes/Lysosomes
Wang, Z., Miao, G., Xue, X., Guo, X., Yuan, C., Wang, Z., Zhang, G., Chen, Y., Feng, D., Hu, J., et al. (2016) · Molecular Cell
Autophagy in Disease and TherapyCellular transport and secretion
Cited by 321
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Crosstalk Between Gut Microbiota and Innate Immunity and Its Implication in Autoimmune Diseases
Jiao, Y., Wu, L., Huntington, N. D., & Zhang, X. (2020) · Frontiers in Immunology
Gut microbiota and healthInflammatory Bowel Disease
Cited by 321
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A continuous correlation between oxidative stress and telomere shortening in fibroblasts
Richter, T., & Zglinicki, T. V. (2007) · Experimental Gerontology
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 321
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Simultaneous Analysis of All SNPs in Genome-Wide and Re-Sequencing Association Studies
Hoggart, C. J., Whittaker, J. C., De Iorio, M., & Balding, D. J. (2008) · PLoS Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 321
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Foxo1 integrates insulin signaling with mitochondrial function in the liver
Cheng, Z., Guo, S., Copps, K., Dong, X., Kollipara, R., Rodgers, J. T., Depinho, R. A., Puigserver, P., & White, M. F. (2009) · Nature Medicine
FOXO transcription factor regulationMetabolism, Diabetes, and Cancer
Cited by 321
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AROMATIZATION OF ANDROSTENEDIONE BY THE DIENCEPHALON1
Naftolin, F., Ryan, K. J., & Petro, Z. (1971) · The Journal of Clinical Endocrinology & Metabolism
Estrogen and related hormone effectsSexual Differentiation and Disorders
Cited by 321
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Identification of rare-disease genes using blood transcriptome sequencing and large control cohorts
Undiagnosed Diseases Network, Frésard, L., Care4Rare Canada Consortium, Smail, C., Ferraro, N. M., Teran, N. A., Li, X., Smith, K. S., Bonner, D., Kernohan, K. D., et al. (2019) · Nature Medicine
Genomics and Rare DiseasesGenomics and Phylogenetic Studies
Cited by 321
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PomBase: a comprehensive online resource for fission yeast
Wood, V., Harris, M. A., McDowall, M. D., Rutherford, K., Vaughan, B. W., Staines, D. M., Aslett, M., Lock, A., Bahler, J., Kersey, P. J., et al. (2012) · Nucleic Acids Research
Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks
Cited by 321
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Fisher, Medawar, Hamilton and the Evolution of Aging
Charlesworth, B. (2000) · Genetics
Genetics, Aging, and Longevity in Model OrganismsPhilosophy of Biology and Scientific Explanation
Cited by 321
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Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2
Barford, D., & Neel, B. G. (1998) · Structure
Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling
Cited by 321
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The DNA damage response to transcription stress
Lans, H., Hoeijmakers, J. H. J., Vermeulen, W., & Marteijn, J. A. (2019) · Nature Reviews Molecular Cell Biology
DNA Repair MechanismsNuclear Structure and Function
Cited by 321
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VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling
Tammela, T., Zarkada, G., Nurmi, H., Jakobsson, L., Heinolainen, K., Tvorogov, D., Zheng, W., Franco, C. A., Murtomäki, A., Aranda, E., et al. (2011) · Nature Cell Biology
Angiogenesis and VEGF in CancerLymphatic System and Diseases
Cited by 321
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High-definition spatial transcriptomic profiling of immune cell populations in colorectal cancer
Oliveira, M. F. D., Romero, J. P., Chung, M., Williams, S. R., Gottscho, A. D., Gupta, A., Pilipauskas, S. E., Mohabbat, S., Raman, N., Sukovich, D. J., et al. (2025) · Nature Genetics
Single-cell and spatial transcriptomicsCancer Immunotherapy and Biomarkers
Cited by 321
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Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness during stress
Escusa-Toret, S., Vonk, W. I. M., & Frydman, J. (2013) · Nature Cell Biology
Heat shock proteins researchEndoplasmic Reticulum Stress and Disease
Cited by 321
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