Most cited biochemistry, genetics and molecular biology papers
- Verified
Atypical mitogen-activated protein kinases: Structure, regulation and functions
Coulombe, P., & Meloche, S. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling
Cited by 298
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MATING TYPE IN FILAMENTOUS FUNGI
Kronstad, J. W., & Staben, C. (1997) · Annual Review of Genetics
Fungal and yeast genetics researchBacterial Genetics and Biotechnology
Cited by 298
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EpiFactors: a comprehensive database of human epigenetic factors and complexes
Medvedeva, Y. A., Lennartsson, A., Ehsani, R., Kulakovskiy, I. V., Vorontsov, I. E., Panahandeh, P., Khimulya, G., Kasukawa, T., The FANTOM Consortium, & Drabløs, F. (2015) · Database
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 298
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Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescence
Lee, S., Jeong, S.-Y., Lim, W.-C., Kim, S., Park, Y.-Y., Sun, X., Youle, R. J., & Cho, H. (2007) · Journal of Biological Chemistry
Mitochondrial Function and PathologyTelomeres, Telomerase, and Senescence
Cited by 298
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Enzymatic Depletion of Tumor Hyaluronan Induces Antitumor Responses in Preclinical Animal Models
Thompson, C. B., Shepard, H. M., O'Connor, P. M., Kadhim, S., Jiang, P., Osgood, R. J., Bookbinder, L. H., Li, X., Sugarman, B. J., Connor, R. J., et al. (2010) · Molecular Cancer Therapeutics
Proteoglycans and glycosaminoglycans researchHydrogels: synthesis, properties, applications
Cited by 298
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Mitochondria and cellular oxygen sensing in the HIF pathway
Taylor, C. T. (2008) · Biochemical Journal
Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress
Cited by 298
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Serum Amyloid A Activates the NLRP3 Inflammasome via P2X7 Receptor and a Cathepsin B-Sensitive Pathway
Niemi, K., Teirilä, L., Lappalainen, J., Rajamäki, K., Baumann, M. H., Öörni, K., Wolff, H., Kovanen, P. T., Matikainen, S., & Eklund, K. K. (2011) · The Journal of Immunology
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 298
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Allosteric inhibition of SHP2: identification of a potent, selective, and orally efficacious phosphatase inhibitor
Garcia Fortanet, J., Chen, C. H.-T., Chen, Y.-N. P., Chen, Z., Deng, Z., Firestone, B., Fekkes, P., Fodor, M., Fortin, P. D., Fridrich, C., et al. (2016) · Journal of Medicinal Chemistry
Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling
Cited by 298
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Genetic Ablation of Polysialic Acid Causes Severe Neurodevelopmental Defects Rescued by Deletion of the Neural Cell Adhesion Molecule
Weinhold, B., Seidenfaden, R., Röckle, I., Mühlenhoff, M., Schertzinger, F., Conzelmann, S., Marth, J. D., Gerardy-Schahn, R., & Hildebrandt, H. (2005) · Journal of Biological Chemistry
Glycosylation and Glycoproteins ResearchNeurogenesis and neuroplasticity mechanisms
Cited by 298
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Direct Comparison of Human Mesenchymal Stem Cells Derived from Adipose Tissues and Bone Marrow in Mediating Neovascularization in Response to Vascular Ischemia
Kim, Y. J., Kim, H. K., Cho, H. H., Bae, Y. C., Suh, K. T., & Jung, J. S. (2007) · Cellular Physiology and Biochemistry
Mesenchymal stem cell researchAngiogenesis and VEGF in Cancer
Cited by 298
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Characterization of four lipoprotein classes in human cerebrospinal fluid
Koch, S., Donarski, N., Goetze, K., Kreckel, M., Stuerenburg, H.-J., Buhmann, C., & Beisiegel, U. (2001) · Journal of Lipid Research
Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health
Cited by 298
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Differentiation of spinal motor neurons from pluripotent human stem cells
Hu, B.-Y., & Zhang, S.-C. (2009) · Nature Protocols
Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms
Cited by 298
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TWINKLE Has 5' −>3' DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein
Korhonen, J. A., Gaspari, M., & Falkenberg, M. (2003) · Journal of Biological Chemistry
DNA Repair MechanismsMitochondrial Function and Pathology
Cited by 298
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Enhanced autophagy ameliorates cardiac proteinopathy
Bhuiyan, M. S., Pattison, J. S., Osinska, H., James, J., Gulick, J., McLendon, P. M., Hill, J. A., Sadoshima, J., & Robbins, J. (2013) · Journal of Clinical Investigation
Autophagy in Disease and TherapyHeat shock proteins research
Cited by 298
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Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase‐3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin
Welsh, G. I., Miller, C. M., Loughlin, A. J., & Price, N. T. (1998) · FEBS Letters
PI3K/AKT/mTOR signaling in cancerRNA and protein synthesis mechanisms
Cited by 298
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Catalase and glutathione peroxidase are equally active in detoxification of hydrogen peroxide in human erythrocytes
Gaetani, G., Galiano, S., Canepa, L., Ferraris, A., & Kirkman, H. (1989) · Blood
Redox biology and oxidative stressNeonatal Health and Biochemistry
Cited by 298
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Modulation of Insulin Receptor Substrate-1 Tyrosine Phosphorylation and Function by Mitogen-activated Protein Kinase
De Fea, K., & Roth, R. A. (1997) · Journal of Biological Chemistry
Protein Kinase Regulation and GTPase SignalingMetabolism, Diabetes, and Cancer
Cited by 298
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Improvement of Obesity and Glucose Tolerance by Acetate in Type 2 Diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) Rats
YAMASHITA, H., FUJISAWA, K., ITO, E., IDEI, S., KAWAGUCHI, N., KIMOTO, M., HIEMORI, M., & TSUJI, H. (2007) · Bioscience, Biotechnology, and Biochemistry
Peroxisome Proliferator-Activated ReceptorsLipid metabolism and biosynthesis
Cited by 297
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Targeted Delivery of CRISPR/Cas9‐Mediated Cancer Gene Therapy via Liposome‐Templated Hydrogel Nanoparticles
Chen, Z., Liu, F., Chen, Y., Liu, J., Wang, X., Chen, A. T., Deng, G., Zhang, H., Liu, J., Hong, Z., et al. (2017) · Advanced Functional Materials
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 297
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Birth of a Photosynthetic Chassis: A MoClo Toolkit Enabling Synthetic Biology in the Microalga Chlamydomonas reinhardtii
Crozet, P., Navarro, F. J., Willmund, F., Mehrshahi, P., Bakowski, K., Lauersen, K. J., Pérez-Pérez, M.-E., Auroy, P., Gorchs Rovira, A., Sauret-Gueto, S., et al. (2018) · ACS Synthetic Biology
Microbial Metabolic Engineering and BioproductionAlgal biology and biofuel production
Cited by 297
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Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice
Chen, Y., Lüttmann, F. F., Schoger, E., Schöler, H. R., Zelarayán, L. C., Kim, K.-P., Haigh, J. J., Kim, J., & Braun, T. (2021) · Science
Congenital heart defects researchPluripotent Stem Cells Research
Cited by 297
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Non-genomic effects of glucocorticoids: an updated view
Panettieri, R. A., Schaafsma, D., Amrani, Y., Koziol-White, C., Ostrom, R., & Tliba, O. (2019) · Trends in Pharmacological Sciences
Estrogen and related hormone effectsAdrenal Hormones and Disorders
Cited by 297
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Emerging role of exosomes in cancer therapy: progress and challenges
Li, J., Wang, J., & Chen, Z. (2025) · Molecular Cancer
Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery
Cited by 297
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The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes
Kasper, L., König, A., Koenig, P.-A., Gresnigt, M. S., Westman, J., Drummond, R. A., Lionakis, M. S., Groß, O., Ruland, J., Naglik, J. R., et al. (2018) · Nature Communications
Inflammasome and immune disordersAntifungal resistance and susceptibility
Cited by 297
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