Most cited biochemistry, genetics and molecular biology papers
- Verified
p21 maintains senescent cell viability under persistent DNA damage response by restraining JNK and caspase signaling
Yosef, R., Pilpel, N., Papismadov, N., Gal, H., Ovadya, Y., Vadai, E., Miller, S., Porat, Z., Ben‐Dor, S., & Krizhanovsky, V. (2017) · The EMBO Journal
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 293
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The functional nitrite reductase activity of the heme-globins
Gladwin, M. T., & Kim-Shapiro, D. B. (2008) · Blood
Hemoglobin structure and functionHeme Oxygenase-1 and Carbon Monoxide
Cited by 293
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Blockade of dendritic cell development by bacterial fermentation products butyrate and propionate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases
Singh, N., Thangaraju, M., Prasad, P. D., Martin, P. M., Lambert, N. A., Boettger, T., Offermanns, S., & Ganapathy, V. (2010) · Journal of Biological Chemistry
Gut microbiota and healthImmunotherapy and Immune Responses
Cited by 293
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Constitutively Active Inflammasome in Human Melanoma Cells Mediating Autoinflammation via Caspase-1 Processing and Secretion of Interleukin-1β
Okamoto, M., Liu, W., Luo, Y., Tanaka, A., Cai, X., Norris, D. A., Dinarello, C. A., & Fujita, M. (2010) · Journal of Biological Chemistry
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 293
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Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not?
De Bock, K., Mazzone, M., & Carmeliet, P. (2011) · Nature Reviews Clinical Oncology
Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism
Cited by 293
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Structural & functional consequences of chronic psychosocial stress on the microbiome & host
Bharwani, A., Mian, M. F., Foster, J. A., Surette, M. G., Bienenstock, J., & Forsythe, P. (2016) · Psychoneuroendocrinology
Gut microbiota and healthTryptophan and brain disorders
Cited by 293
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Predominant α2/β2/γ3 AMPK activation during exercise in human skeletal muscle
Birk, J. B., & Wojtaszewski, J. F. P. (2006) · The Journal of Physiology
Metabolism, Diabetes, and CancerCardiovascular and exercise physiology
Cited by 293
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Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform
Denning, C., Borgdorff, V., Crutchley, J., Firth, K. S. A., George, V., Kalra, S., Kondrashov, A., Hoang, M. D., Mosqueira, D., Patel, A., et al. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias
Cited by 293
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Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells
d'Adda di Fagagna, F., Hande, M. P., Tong, W.-M., Roth, D., Lansdorp, P. M., Wang, Z.-Q., & Jackson, S. P. (2001) · Current Biology
Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms
Cited by 293
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Human apolipoprotein E3 in aqueous solution. I. Evidence for two structural domains.
Wetterau, J. R., Aggerbeck, L. P., Rall, S. C., & Weisgraber, K. H. (1988) · Journal of Biological Chemistry
Protein Structure and DynamicsProtein purification and stability
Cited by 293
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Life without a wall or division machine in Bacillus subtilis
Leaver, M., Domínguez-Cuevas, P., Coxhead, J. M., Daniel, R. A., & Errington, J. (2009) · Nature
Bacterial Genetics and BiotechnologyBiochemical and Structural Characterization
Cited by 293
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Calorie restriction and prevention of age‐associated chronic disease
Omodei, D., & Fontana, L. (2011) · FEBS Letters
Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health
Cited by 293
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Association of DNA Polymerase μ (pol μ) with Ku and Ligase IV: Role for pol μ in End-Joining Double-Strand Break Repair
Mahajan, K. N., Nick McElhinny, S. A., Mitchell, B. S., & Ramsden, D. A. (2002) · Molecular and Cellular Biology
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 293
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Mutation analysis of peroxisome proliferator-activated receptor-γ coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus
Ek, J., Andersen, G., Urhammer, S. A., Gæde, P. H., Drivsholm, T., Borch-Johnsen, K., Hansen, T., & Pedersen, O. (2001) · Diabetologia
Peroxisome Proliferator-Activated ReceptorsGenetic Associations and Epidemiology
Cited by 293
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A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9
Dagdas, Y. S., Chen, J. S., Sternberg, S. H., Doudna, J. A., & Yildiz, A. (2017) · Science Advances
CRISPR and Genetic EngineeringDNA and Nucleic Acid Chemistry
Cited by 293
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Inhibition of tumor propellant glutathione peroxidase 4 induces ferroptosis in cancer cells and enhances anticancer effect of cisplatin
Zhang, X., Sui, S., Wang, L., Li, H., Zhang, L., Xu, S., & Zheng, X. (2020) · Journal of Cellular Physiology
Ferroptosis and cancer prognosisSelenium in Biological Systems
Cited by 293
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Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice
Halliday, M., Radford, H., Zents, K. A. M., Molloy, C., Moreno, J. A., Verity, N. C., Smith, E., Ortori, C. A., Barrett, D. A., Bushell, M., et al. (2017) · Brain
Endoplasmic Reticulum Stress and DiseaseAlzheimer's disease research and treatments
Cited by 293
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Arabidopsis OR proteins are the major posttranscriptional regulators of phytoene synthase in controlling carotenoid biosynthesis
Zhou, X., Welsch, R., Yang, Y., Álvarez, D., Riediger, M., Yuan, H., Fish, T., Liu, J., Thannhauser, T. W., & Li, L. (2015) · Proceedings of the National Academy of Sciences
Plant biochemistry and biosynthesisPlant Gene Expression Analysis
Cited by 293
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Small nucleolar RNA signatures as biomarkers for non-small-cell lung cancer
Liao, J., Yu, L., Mei, Y., Guarnera, M., Shen, J., Li, R., Liu, Z., & Jiang, F. (2010) · Molecular Cancer
Cancer-related molecular mechanisms researchLung Cancer Research Studies
Cited by 293
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Shared Synaptic Pathophysiology in Syndromic and Nonsyndromic Rodent Models of Autism
Baudouin, S. J., Gaudias, J., Gerharz, S., Hatstatt, L., Zhou, K., Punnakkal, P., Tanaka, K. F., Spooren, W., Hen, R., De Zeeuw, C. I., et al. (2012) · Science
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 293
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Molecular crowding limits translation and cell growth
Klumpp, S., Scott, M., Pedersen, S., & Hwa, T. (2013) · Proceedings of the National Academy of Sciences
RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology
Cited by 293
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Genome‐Wide Association Study of Alcohol Dependence Implicates a Region on Chromosome 11
Edenberg, H. J., Koller, D. L., Xuei, X., Wetherill, L., McClintick, J. N., Almasy, L., Bierut, L. J., Bucholz, K. K., Goate, A., Aliev, F., et al. (2010) · Alcoholism: Clinical and Experimental Research
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 293
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ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness through Activation of the Unfolded Protein Response
Heijmans, J., van Lidth de Jeude, J. F., Koo, B.-K., Rosekrans, S. L., Wielenga, M. C. B., van de Wetering, M., Ferrante, M., Lee, A. S., Onderwater, J. J. M., Paton, J. C., et al. (2013) · Cell Reports
Endoplasmic Reticulum Stress and DiseaseIon Channels and Receptors
Cited by 293
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A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes
Lage, K., Hansen, N. T., Karlberg, E. O., Eklund, A. C., Roque, F. S., Donahoe, P. K., Szallasi, Z., Jensen, T. S., & Brunak, S. (2008) · Proceedings of the National Academy of Sciences
Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies
Cited by 292
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