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Mechanisms of aging: an appraisal of the oxidative stress hypothesis1,2 1This article is part of a series of reviews on “Oxidative Stress and Aging.” The full list of papers may be found on the homepage of the journal. 2Guest Editor: Rajindar S. Sohal

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Brain IRS2 Signaling Coordinates Life Span and Nutrient Homeostasis

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Transgenic Mice with a Reduced Core Body Temperature Have an Increased Life Span

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Long-term caloric restriction ameliorates the decline in diastolic function in humans

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Calorie restriction and cancer prevention: metabolic and molecular mechanisms

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Caloric Restriction, the Traditional Okinawan Diet, and Healthy Aging: The Diet of the World's Longest‐Lived People and Its Potential Impact on Morbidity and Life Span

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Type 5 Adenylyl Cyclase Disruption Increases Longevity and Protects Against Stress

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The overexpression of major antioxidant enzymes does not extend the lifespan of mice

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ENERGY INTAKE, MEAL FREQUENCY, AND HEALTH: A Neurobiological Perspective

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Hormone-Treated Snell Dwarf Mice Regain Fertility But Remain Long Lived and Disease Resistant

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Effect of Long-Term Calorie Restriction With Adequate Protein and Micronutrients on Thyroid Hormones

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Attenuation of sarcopenia by dietary restriction in rhesus monkeys

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Dietary Restriction Reduces Atherosclerosis and Oxidative Stress in the Aorta of Apolipoprotein E-Deficient Mice

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Long‐term effects of calorie restriction on serum sex‐hormone concentrations in men

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