Most cited biochemistry, genetics and molecular biology papers
- Verified
Xenome—a tool for classifying reads from xenograft samples
Conway, T., Wazny, J., Bromage, A., Tymms, M., Sooraj, D., Williams, E. D., & Beresford-Smith, B. (2012) · Bioinformatics
Genomics and Phylogenetic StudiesGene expression and cancer classification
Cited by 276
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Feedback control of cyclooxygenase-2 expression through PPARγ
Inoue, H., Tanabe, T., & Umesono, K. (2000) · Journal of Biological Chemistry
Peroxisome Proliferator-Activated ReceptorsInflammatory mediators and NSAID effects
Cited by 276
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MicroRNAs acting in a double-negative feedback loop to control a neuronal cell fate decision
Johnston, R. J., Chang, S., Etchberger, J. F., Ortiz, C. O., & Hobert, O. (2005) · Proceedings of the National Academy of Sciences
Developmental Biology and Gene RegulationMicroRNA in disease regulation
Cited by 276
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Purification and properties of NADP-dependent formate dehydrogenase from Clostridium thermoaceticum, a tungsten–selenium–iron protein
Yamamoto, I., Saiki, T., Liu, S. M., & Ljungdahl, L. G. (1983) · Journal of Biological Chemistry
Metalloenzymes and iron-sulfur proteinsMicrobial metabolism and enzyme function
Cited by 276
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Retinoic acid signaling pathways in development and diseases
Das, B. C., Thapa, P., Karki, R., Das, S., Mahapatra, S., Liu, T.-C., Torregroza, I., Wallace, D. P., Kambhampati, S., Van Veldhuizen, P., et al. (2014) · Bioorganic & Medicinal Chemistry
Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors
Cited by 276
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Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen
Li, X., Li, J., Harrington, J., Lieber, M. R., & Burgers, P. M. J. (1995) · Journal of Biological Chemistry
DNA Repair MechanismsDNA and Nucleic Acid Chemistry
Cited by 276
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The p16INK4a-RB pathway : molecular link between cellular senescence and tumor suppression
Ohtani, N., Yamakoshi, K., Takahashi, A., & Hara, E. (2004) · The Journal of Medical Investigation
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 276
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Risk of tumorigenesis in overgrowth syndromes: a comprehensive review
Lapunzina, P. (2005) · American Journal of Medical Genetics Part C Seminars in Medical Genetics
Genetic Syndromes and ImprintingSarcoma Diagnosis and Treatment
Cited by 276
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Targeting Transcription Factors in Cancer
Bhagwat, A. S., & Vakoc, C. R. (2015) · Trends in Cancer
Protein Degradation and InhibitorsChromatin Remodeling and Cancer
Cited by 276
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Structural Basis for Regulation of Phosphoinositide Kinases and Their Involvement in Human Disease
Burke, J. E. (2018) · Molecular Cell
PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling
Cited by 276
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Elevation of Mitochondrial Transmembrane Potential and Reactive Oxygen Intermediate Levels Are Early Events and Occur Independently from Activation of Caspases in Fas Signaling
Banki, K., Hutter, E., Gonchoroff, N. J., & Perl, A. (1999) · The Journal of Immunology
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 276
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Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity
Akbari, P., Gilani, A., Sosina, O., Kosmicki, J. A., Khrimian, L., Fang, Y.-Y., Persaud, T., Garcia, V., Sun, D., Li, A., et al. (2021) · Science
Genetic Associations and EpidemiologyRegulation of Appetite and Obesity
Cited by 276
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Inflammation induced loss of skeletal muscle
Londhe, P., & Guttridge, D. C. (2015) · Bone
Muscle Physiology and DisordersInflammatory Myopathies and Dermatomyositis
Cited by 276
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Galactose Enhances Oxidative Metabolism and Reveals Mitochondrial Dysfunction in Human Primary Muscle Cells
Aguer, C., Gambarotta, D., Mailloux, R. J., Moffat, C., Dent, R., McPherson, R., & Harper, M.-E. (2011) · PLoS ONE
Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer
Cited by 276
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Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
Osorio, F. G., Bárcena, C., Soria-Valles, C., Ramsay, A. J., de Carlos, F., Cobo, J., Fueyo, A., Freije, J. M. P., & López-Otín, C. (2012) · Genes & Development
Nuclear Structure and FunctionGenetics, Aging, and Longevity in Model Organisms
Cited by 276
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RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors
Willnow, T. E., Rohlmann, A., Horton, J., Otani, H., Braun, J. R., Hammer, R. E., & Herz, J. (1996) · The EMBO Journal
Cholesterol and Lipid MetabolismHeat shock proteins research
Cited by 276
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Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways †
Nishimura, Y., Martin, C. L., Vazquez-Lopez, A., Spence, S. J., Alvarez-Retuerto, A. I., Sigman, M., Steindler, C., Pellegrini, S., Schanen, N. C., Warren, S. T., et al. (2007) · Human Molecular Genetics
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 276
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WRM-1 Activates the LIT-1 Protein Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans
Rocheleau, C. E., Yasuda, J., Shin, T. H., Lin, R., Sawa, H., Okano, H., Priess, J. R., Davis, R. J., & Mello, C. C. (1999) · Cell
Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation
Cited by 276
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Mitochondrial complex I: structure, function and pathology
Janssen, R. J. R. J., Nijtmans, L. G., Heuvel, L. P. V. D., & Smeitink, J. A. M. (2006) · Journal of Inherited Metabolic Disease
Mitochondrial Function and PathologyEnzyme Structure and Function
Cited by 276
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Multistationarity, the basis of cell differentiation and memory. I. Structural conditions of multistationarity and other nontrivial behavior
Thomas, R., & Kaufman, M. (2001) · Chaos: An Interdisciplinary Journal of Nonlinear Science
Gene Regulatory Network AnalysisAdvanced Differential Equations and Dynamical Systems
Cited by 276
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LC3-Associated Phagocytosis and Inflammation
Heckmann, B. L., Boada-Romero, E., Cunha, L. D., Magne, J., & Green, D. R. (2017) · Journal of Molecular Biology
Autophagy in Disease and TherapyPhagocytosis and Immune Regulation
Cited by 276
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In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9-activator transgenic mice
Zhou, H., Liu, J., Zhou, C., Gao, N., Rao, Z., Li, H., Hu, X., Li, C., Yao, X., Shen, X., et al. (2018) · Nature Neuroscience
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 276
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Digital RNA sequencing minimizes sequence-dependent bias and amplification noise with optimized single-molecule barcodes
Shiroguchi, K., Jia, T. Z., Sims, P. A., & Xie, X. S. (2012) · Proceedings of the National Academy of Sciences
Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics
Cited by 276
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Glucocorticoids: exemplars of multi-tasking
Buckingham, J. C. (2006) · British Journal of Pharmacology
Estrogen and related hormone effectsAdrenal Hormones and Disorders
Cited by 276
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