Most cited medicine papers
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Enlarged perivascular spaces on MRI are a feature of cerebral small vessel disease
Doubal, F. N., MacLullich, A. M. J., Ferguson, K. J., Dennis, M. S., & Wardlaw, J. M. (2010) · Stroke
Cerebrovascular and genetic disordersIntracerebral and Subarachnoid Hemorrhage Research
Cited by 904
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Skeletal muscle performance and ageing
Tieland, M., Trouwborst, I., & Clark, B. C. (2018) · Journal of Cachexia, Sarcopenia and Muscle
Nutrition and Health in AgingMuscle Physiology and Disorders
Cited by 904
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A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage
Tanaka, H., Arakawa, H., Yamaguchi, T., Shiraishi, K., Fukuda, S., Matsui, K., Takei, Y., & Nakamura, Y. (2000) · Nature
Cancer-related Molecular PathwaysDNA Repair Mechanisms
Cited by 904
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Causes and frequency of blindness in patients with intraocular inflammatory disease.
Rothova, A., Suttorp-van Schulten, M. S., Frits Treffers, W., & Kijlstra, A. (1996) · British Journal of Ophthalmology
Ocular Diseases and Behçet’s SyndromeOcular Infections and Treatments
Cited by 904
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SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
Rui, L., Yuan, M., Frantz, D., Shoelson, S., & White, M. F. (2002) · Journal of Biological Chemistry
Adipokines, Inflammation, and Metabolic DiseasesCytokine Signaling Pathways and Interactions
Cited by 904
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Hypothalamic insulin signaling is required for inhibition of glucose production
Obici, S., Zhang, B. B., Karkanias, G., & Rossetti, L. (2002) · Nature Medicine
Pancreatic function and diabetesRegulation of Appetite and Obesity
Cited by 904
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Life Expectancy of Patients With Chronic Myeloid Leukemia Approaches the Life Expectancy of the General Population
Bower, H., Björkholm, M., Dickman, P. W., Höglund, M., Lambert, P. C., & Andersson, T. M.-L. (2016) · Journal of Clinical Oncology
Chronic Myeloid Leukemia TreatmentsGlobal Cancer Incidence and Screening
Cited by 904
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New clues about vitamin D functions in the nervous system
Garcion, E., Wion-Barbot, N., Montero-Menei, C. N., Berger, F., & Wion, D. (2002) · Trends in Endocrinology & Metabolism
Vitamin D Research StudiesNeurological Disease Mechanisms and Treatments
Cited by 904
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Chronic Autoimmune Thyroiditis
Dayan, C. M., & Daniels, G. H. (1996) · New England Journal of Medicine
Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment
Cited by 904
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Overview of resistance to systemic therapy in patients with breast cancer
Gonzalez-Angulo, A. M., Morales-Vasquez, F., & Hortobagyi, G. N. (2007) · Advances in Experimental Medicine and Biology
Drug Transport and Resistance MechanismsBreast Cancer Treatment Studies
Cited by 904
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Fecal microbiota transplantation for Clostridium difficile infection: systematic review and meta-analysis
Kassam, Z., Lee, C. H., Yuan, Y., & Hunt, R. H. (2013) · American Journal of Gastroenterology
Clostridium difficile and Clostridium perfringens researchGut microbiota and health
Cited by 904
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Appropriate waist circumference cutoff points for central obesity in Korean adults
Lee, S. Y., Park, H. S., Kim, D. J., Han, J. H., Kim, S. M., Cho, G. J., Kim, D. Y., Kwon, H. S., Kim, S. R., Lee, C. B., et al. (2007) · Diabetes Research and Clinical Practice
Diabetes, Cardiovascular Risks, and LipoproteinsBody Composition Measurement Techniques
Cited by 904
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Classification of amyloidosis by laser microdissection and mass spectrometry–based proteomic analysis in clinical biopsy specimens
Vrana, J. A., Gamez, J. D., Madden, B. J., Theis, J. D., Bergen, H. R., & Dogan, A. (2009) · Blood
Amyloidosis: Diagnosis, Treatment, OutcomesAdvanced Proteomics Techniques and Applications
Cited by 904
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Efficacy and Safety of Flexibly Dosed Esketamine Nasal Spray Combined With a Newly Initiated Oral Antidepressant in Treatment-Resistant Depression: A Randomized Double-Blind Active-Controlled Study
Popova, V., Daly, E. J., Trivedi, M., Cooper, K., Lane, R., Lim, P., Mazzucco, C., Hough, D., Thase, M. E., Shelton, R. C., et al. (2019) · American Journal of Psychiatry
Treatment of Major DepressionElectroconvulsive Therapy Studies
Cited by 904
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Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment
Pfaller, M. A. (2012) · The American Journal of Medicine
Antifungal resistance and susceptibilityFungal Plant Pathogen Control
Cited by 903
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Patient and Caregiver Characteristics and Nursing Home Placement in Patients With Dementia
Yaffe, K. (2002) · JAMA
Geriatric Care and Nursing HomesDementia and Cognitive Impairment Research
Cited by 903
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Using the rat forced swim test to assess antidepressant-like activity in rodents
Slattery, D. A., & Cryan, J. F. (2012) · Nature Protocols
Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior
Cited by 903
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Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma
Zhao, J., Chen, A. X., Gartrell, R. D., Silverman, A. M., Aparicio, L., Chu, T., Bordbar, D., Shan, D., Samanamud, J., Mahajan, A., et al. (2019) · Nature Medicine
Cancer Immunotherapy and BiomarkersGlioma Diagnosis and Treatment
Cited by 903
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Subclinical hypothyroidism and pregnancy outcomes
Casey, B. M., Dashe, J. S., Wells, C. E., McIntire, D. D., Byrd, W., Leveno, K. J., & Cunningham, F. G. (2005) · Obstetrics & Gynecology
Thyroid Disorders and TreatmentsPregnancy and preeclampsia studies
Cited by 903
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Nitric oxide in health and disease of the respiratory system
Ricciardolo, F. L. M., Sterk, P. J., Gaston, B., & Folkerts, G. (2004) · Physiological Reviews
Nitric Oxide and Endothelin EffectsAsthma and respiratory diseases
Cited by 903
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Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line.
Drucker, D. J., Philippe, J., Mojsov, S., Chick, W. L., & Habener, J. F. (1987) · Proceedings of the National Academy of Sciences
Pancreatic function and diabetesDiabetes Treatment and Management
Cited by 903
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AMPK and SIRT1: a long-standing partnership?
Ruderman, N. B., Julia Xu, X., Nelson, L., Cacicedo, J. M., Saha, A. K., Lan, F., & Ido, Y. (2010) · American Journal of Physiology-Endocrinology and Metabolism
Sirtuins and Resveratrol in MedicineMetabolism, Diabetes, and Cancer
Cited by 903
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Efficacy and adverse effects of atypical antipsychotics for dementia: meta-analysis of randomized, placebo-controlled trials
Schneider, L. S., Dagerman, K., & Insel, P. S. (2006) · The American Journal of Geriatric Psychiatry
Dementia and Cognitive Impairment ResearchSchizophrenia research and treatment
Cited by 903
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Molecular mechanisms of diabetic cardiomyopathy
Bugger, H., & Abel, E. D. (2014) · Diabetologia
Cardiovascular Function and Risk FactorsCardiac Fibrosis and Remodeling
Cited by 903
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