Check pharmacology, toxicology and pharmaceutics papers: citations, claims and retractions

Artificial intelligence in drug discovery: recent advances and future perspectives

Jiménez-Luna, J., Grisoni, F., Weskamp, N., & Schneider, G. (2021) · Expert Opinion on Drug Discovery

Computational Drug Discovery MethodsMachine Learning in Materials Science

Cited by 464

Fragment-Based Approaches in Drug Discovery and Chemical Biology

Scott, D. E., Coyne, A. G., Hudson, S. A., & Abell, C. (2012) · Biochemistry

Computational Drug Discovery MethodsChemical Synthesis and Analysis

Cited by 460

Machine Learning Methods in Drug Discovery

Patel, L., Shukla, T., Huang, X., Ussery, D. W., & Wang, S. (2020) · Molecules

Computational Drug Discovery MethodsMachine Learning in Materials Science

Cited by 460

Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver

Barter, Z., Bayliss, M., Beaune, P., Boobis, A., Carlile, D., Edwards, R., Brian Houston, J., Lake, B., Lipscomb, J., Pelkonen, O., et al. (2007) · Current Drug Metabolism

Pharmacogenetics and Drug MetabolismPharmaceutical studies and practices

Cited by 459

Small-molecule kinase inhibitors: an analysis of FDA-approved drugs

Wu, P., Nielsen, T. E., & Clausen, M. H. (2016) · Drug Discovery Today

Computational Drug Discovery MethodsProtein Kinase Regulation and GTPase Signaling

Cited by 457

Effects of St. John's wort on irinotecan metabolism.

Mathijssen, R. H. J. (2002) · CancerSpectrum Knowledge Environment

Pharmacogenetics and Drug MetabolismComplementary and Alternative Medicine Studies

Cited by 457

Attention-deficit/hyperactivity disorder and urinary metabolites of organophosphate pesticides

Bouchard, M. F., Bellinger, D. C., Wright, R. O., & Weisskopf, M. G. (2010) · Pediatrics

Pesticide Exposure and ToxicityAttention Deficit Hyperactivity Disorder

Cited by 457

Big data and artificial intelligence modeling for drug discovery

Zhu, H. (2020) · Annual Review of Pharmacology and Toxicology

Computational Drug Discovery MethodsMachine Learning in Materials Science

Cited by 455

Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier

Tang, B. C., Dawson, M., Lai, S. K., Wang, Y.-Y., Suk, J. S., Yang, M., Zeitlin, P., Boyle, M. P., Fu, J., & Hanes, J. (2009) · Proceedings of the National Academy of Sciences

Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery

Cited by 453

Population-Based Mechanistic Prediction of Oral Drug Absorption

Jamei, M., Turner, D., Yang, J., Neuhoff, S., Polak, S., Rostami-Hodjegan, A., & Tucker, G. (2009) · The AAPS Journal

Drug Solubulity and Delivery SystemsPharmaceutical studies and practices

Cited by 452

Tailoring Formulations for Intranasal Nose-to-Brain Delivery: A Review on Architecture, Physico-Chemical Characteristics and Mucociliary Clearance of the Nasal Olfactory Mucosa

Gänger, S., & Schindowski, K. (2018) · Pharmaceutics

Advanced Drug Delivery SystemsInhalation and Respiratory Drug Delivery

Cited by 447

Multi-pulse drug delivery from a resorbable polymeric microchip device

Grayson, A. C. R., Choi, I. S., Tyler, B. M., Wang, P. P., Brem, H., Cima, M. J., & Langer, R. (2003) · Nature Materials

Advanced Drug Delivery SystemsMicrofluidic and Capillary Electrophoresis Applications

Cited by 444

Drug repurposing for cancer therapy

Xia, Y., Sun, M., Huang, H., & Jin, W.-L. (2024) · Signal Transduction and Targeted Therapy

Computational Drug Discovery MethodsCancer Mechanisms and Therapy

Cited by 443

Lipid-Based Delivery Systems and Intestinal Lymphatic Drug Transport: A Mechanistic Update

Trevaskis, N. L., Charman, W. N., & Porter, C. J. H. (2008) · Advanced Drug Delivery Reviews

Drug Solubulity and Delivery SystemsAdvanced Drug Delivery Systems

Cited by 442

The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial

Rouphael, N. G., Paine, M., Mosley, R., Henry, S., McAllister, D. V., Kalluri, H., Pewin, W., Frew, P. M., Yu, T., Thornburg, N. J., et al. (2017) · The Lancet

Advancements in Transdermal Drug DeliveryInfluenza Virus Research Studies

Cited by 442

MolGAN: An implicit generative model for small molecular graphs

De Cao, N., & Kipf, T. (2018) · arXiv

Computational Drug Discovery MethodsMachine Learning in Materials Science

Cited by 442

Maternal residence near agricultural pesticide applications and autism spectrum disorders among children in the California central valley

Roberts, E. M., English, P. B., Grether, J. K., Windham, G. C., Somberg, L., & Wolff, C. (2007) · Environmental Health Perspectives

Pesticide Exposure and ToxicityAutism Spectrum Disorder Research

Cited by 442

Advancing the Science for Active Surveillance: Rationale and Design for the Observational Medical Outcomes Partnership

Stang, P. E., Ryan, P. B., Racoosin, J. A., Overhage, J. M., Hartzema, A. G., Reich, C., Welebob, E., Scarnecchia, T., & Woodcock, J. (2010) · Annals of Internal Medicine

Pharmacovigilance and Adverse Drug ReactionsData-Driven Disease Surveillance

Cited by 441

Ocular drug delivery: present innovations and future challenges

Gote, V., Sikder, S., Sicotte, J., & Pal, D. (2019) · The Journal of Pharmacology and Experimental Therapeutics

Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery

Cited by 441

Patients with elevated liver enzymes are not at higher risk for statin hepatotoxicity

Chalasani, N., Aljadhey, H., Kesterson, J., Murray, M. D., & Hall, S. D. (2004) · Gastroenterology

Drug-Induced Hepatotoxicity and ProtectionLipoproteins and Cardiovascular Health

Cited by 441

Risk of first‐generation H 1 ‐antihistamines: a GA 2 LEN position paper

Church, M. K., Maurer, M., Simons, F. E. R., Bindslev‐Jensen, C., Van Cauwenberge, P., Bousquet, J., Holgate, S. T., & Zuberbier, T. (2010) · Allergy

Pharmacovigilance and Adverse Drug ReactionsMast cells and histamine

Cited by 440

Interpreting non-linear drug diffusion data: Utilizing Korsmeyer-Peppas model to study drug release from liposomes

Wu, I. Y., Bala, S., Škalko-Basnet, N., & di Cagno, M. P. (2019) · European Journal of Pharmaceutical Sciences

Advanced Drug Delivery SystemsAdvancements in Transdermal Drug Delivery

Cited by 439

A review of disintegration mechanisms and measurement techniques

Markl, D., & Zeitler, J. A. (2017) · Pharmaceutical Research

Drug Solubulity and Delivery SystemsGranular flow and fluidized beds

Cited by 439

Recognizing Pitfalls in Virtual Screening: A Critical Review

Scior, T., Bender, A., Tresadern, G., Medina-Franco, J. L., Martínez-Mayorga, K., Langer, T., Cuanalo-Contreras, K., & Agrafiotis, D. K. (2012) · Journal of Chemical Information and Modeling

Computational Drug Discovery MethodsSynthesis and Characterization of Heterocyclic Compounds

Cited by 438