Check pharmacology, toxicology and pharmaceutics papers: citations, claims and retractions

Crystal structure of the human σ1 receptor

Schmidt, H. R., Zheng, S., Gurpinar, E., Koehl, A., Manglik, A., & Kruse, A. C. (2016) · Nature

Pharmacological Receptor Mechanisms and EffectsReceptor Mechanisms and Signaling

Cited by 482

Direct nose to brain drug delivery via integrated nerve pathways bypassing the blood–brain barrier: an excellent platform for brain targeting

Pardeshi, C. V., & Belgamwar, V. S. (2013) · Expert Opinion on Drug Delivery

Advanced Drug Delivery SystemsBarrier Structure and Function Studies

Cited by 482

A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose

Cooper, G. M., Johnson, J. A., Langaee, T. Y., Feng, H., Stanaway, I. B., Schwarz, U. I., Ritchie, M. D., Stein, C. M., Roden, D. M., Smith, J. D., et al. (2008) · Blood

Pharmacogenetics and Drug MetabolismGenetic Associations and Epidemiology

Cited by 481

Polymeric micelles for ocular drug delivery: From structural frameworks to recent preclinical studies

Mandal, A., Bisht, R., Rupenthal, I. D., & Mitra, A. K. (2017) · Journal of Controlled Release

Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery

Cited by 481

Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data

Iwatsubo, T., Hirota, N., Ooie, T., Suzuki, H., Shimada, N., Chiba, K., Ishizaki, T., Green, C. E., Tyson, C. A., & Sugiyama, Y. (1997) · Pharmacology & Therapeutics

Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection

Cited by 479

DDT and breast cancer in young women: new data on the significance of age at exposure

Cohn, B. A., Wolff, M. S., Cirillo, P. M., & Sholtz, R. I. (2007) · Environmental Health Perspectives

Pesticide Exposure and ToxicityEffects and risks of endocrine disrupting chemicals

Cited by 477

Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation

LeCluyse, E. L. (2001) · European Journal of Pharmaceutical Sciences

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 477

Potency Trends of Δ 9 ‐THC and Other Cannabinoids in Confiscated Cannabis Preparations from 1993 to 2008*

Mehmedic, Z., Chandra, S., Slade, D., Denham, H., Foster, S., Patel, A. S., Ross, S. A., Khan, I. A., & ElSohly, M. A. (2010) · Journal of Forensic Sciences

Forensic Toxicology and Drug AnalysisCannabis and Cannabinoid Research

Cited by 475

Automated docking to multiple target structures: Incorporation of protein mobility and structural water heterogeneity in AutoDock

Österberg, F., Morris, G. M., Sanner, M. F., Olson, A. J., & Goodsell, D. S. (2002) · Proteins: Structure, Function, and Bioinformatics

Computational Drug Discovery MethodsProtein Structure and Dynamics

Cited by 474

Adverse Drug Event Surveillance and Drug Withdrawals in the United States, 1969-2002: The Importance of Reporting Suspected Reactions

Wysowski, D. K., & Swartz, L. (2005) · Archives of Internal Medicine

Pharmacovigilance and Adverse Drug ReactionsPharmaceutical industry and healthcare

Cited by 471

C-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity

Gunawan, B. K., Liu, Z., Han, D., Hanawa, N., Gaarde, W. A., & Kaplowitz, N. (2006) · Gastroenterology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 471

Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7

Williams, J. A., Ring, B. J., Cantrell, V. E., Jones, D. R., Eckstein, J., Ruterbories, K., Hamman, M. A., Hall, S. D., & Wrighton, S. A. (2002) · Drug Metabolism and Disposition

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 471

Drug repositioning: a brief overview

Jourdan, J.-P., Bureau, R., Rochais, C., & Dallemagne, P. (2020) · Journal of Pharmacy and Pharmacology

Computational Drug Discovery MethodsPharmaceutical Economics and Policy

Cited by 470

Convolutional embedding of attributed molecular graphs for physical property prediction

Coley, C. W., Barzilay, R., Green, W. H., Jaakkola, T. S., & Jensen, K. F. (2017) · Journal of Chemical Information and Modeling

Computational Drug Discovery MethodsGraph theory and applications

Cited by 470

Association of Acetaminophen Hepatotoxicity With Fasting and Ethanol Use

Whitcomb, D. C. (1994) · JAMA: The Journal of the American Medical Association

Drug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments

Cited by 470

SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid

Pasanen, M. K., Neuvonen, M., Neuvonen, P. J., & Niemi, M. (2006) · Pharmacogenetics and Genomics

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 470

Antioxidant activity of rosemary (Rosmarinus officinalis L.) essential oil and its hepatoprotective potential

Rašković, A., Milanović, I., Pavlović, N., Ćebović, T., Vukmirović, S., & Mikov, M. (2014) · BMC Complementary and Alternative Medicine

Drug-Induced Hepatotoxicity and ProtectionEssential Oils and Antimicrobial Activity

Cited by 470

Can we rationally design promiscuous drugs?

HOPKINS, A., MASON, J., & OVERINGTON, J. (2006) · Current Opinion in Structural Biology

Computational Drug Discovery MethodsProtein Degradation and Inhibitors

Cited by 469

Effective drug combinations in breast, colon and pancreatic cancer cells

Jaaks, P., Coker, E. A., Vis, D. J., Edwards, O., Carpenter, E. F., Leto, S. M., Dwane, L., Sassi, F., Lightfoot, H., Barthorpe, S., et al. (2022) · Nature

Computational Drug Discovery MethodsCancer Genomics and Diagnostics

Cited by 469

Variability in docking success rates due to dataset preparation.

Corbeil, C. R., Williams, C. I., & Labute, P. (2012) · Journal of Computer-Aided Molecular Design

Computational Drug Discovery MethodsProtein Structure and Dynamics

Cited by 469

Nasal mucociliary clearance as a factor in nasal drug delivery

Marttin, E., Schipper, N. G. M., Verhoef, J. C., & Merkus, F. W. H. M. (1998) · Advanced Drug Delivery Reviews

Advanced Drug Delivery SystemsInhalation and Respiratory Drug Delivery

Cited by 469

How not to develop a quantitative structure–activity or structure–property relationship (QSAR/QSPR)

Dearden, J. C., Cronin, M. T. D., & Kaiser, K. L. E. (2009) · SAR and QSAR in Environmental Research

Computational Drug Discovery MethodsAdvanced Chemical Physics Studies

Cited by 468

An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease

Zhang, S., Ermann, J., Succi, M. D., Zhou, A., Hamilton, M. J., Cao, B., Korzenik, J. R., Glickman, J. N., Vemula, P. K., Glimcher, L. H., et al. (2015) · Science Translational Medicine

Advanced Drug Delivery SystemsInflammatory Bowel Disease

Cited by 467

IBM Watson: How Cognitive Computing Can Be Applied to Big Data Challenges in Life Sciences Research

Chen, Y., Elenee Argentinis, J., & Weber, G. (2016) · Clinical Therapeutics

Computational Drug Discovery MethodsBiomedical Text Mining and Ontologies

Cited by 466