Most cited pharmacology, toxicology and pharmaceutics papers
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Predicting Drug-Induced Liver Injury with Bayesian Machine Learning
Williams, D. P., Lazic, S. E., Foster, A. J., Semenova, E., & Morgan, P. (2020) · Chemical Research in Toxicology
Drug-Induced Hepatotoxicity and ProtectionComputational Drug Discovery Methods
Cited by 124
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Oral pharmacokinetics of the anti-HIV efavirenz encapsulated within polymeric micelles
Chiappetta, D. A., Hocht, C., Taira, C., & Sosnik, A. (2011) · Biomaterials
Drug Solubulity and Delivery SystemsAdvanced Drug Delivery Systems
Cited by 124
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Drug-induced liver injury: a clinical update
Ghabril, M., Chalasani, N., & Björnsson, E. (2010) · Current Opinion in Gastroenterology
Drug-Induced Hepatotoxicity and ProtectionDrug-Induced Adverse Reactions
Cited by 123
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CASE-CONTROL STUDIES IN THE EVALUATION OF DRUG-INDUCED ILLNESS
JICK, H., & VESSEY, M. P. (1978) · American Journal of Epidemiology
Pharmacovigilance and Adverse Drug ReactionsStatistical Methods in Epidemiology
Cited by 123
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Examination of some factors responsible for a food‐induced increase in absorption of atovaquone.
Rolan, P., Mercer, A., Weatherley, B., Holdich, T., Meire, H., Peck, R., Ridout, G., & Posner, J. (1994) · British Journal of Clinical Pharmacology
Drug Solubulity and Delivery SystemsPharmacogenetics and Drug Metabolism
Cited by 123
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Oral fluid drug testing: analytical approaches, issues and interpretation of results
Desrosiers, N. A., & Huestis, M. A. (2019) · Journal of Analytical Toxicology
Forensic Toxicology and Drug AnalysisAnalytical chemistry methods development
Cited by 123
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Idiosyncratic Drug-Induced Liver Injury and the Role of Inflammatory Stress with an Emphasis on an Animal Model of Trovafloxacin Hepatotoxicity
Shaw, P. J., Ganey, P. E., & Roth, R. A. (2010) · Toxicological Sciences
Drug-Induced Hepatotoxicity and ProtectionDrug-Induced Adverse Reactions
Cited by 123
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Paclitaxel loaded poly(L-lactic acid) microspheres: Properties of microspheres made with low molecular weight polymers
Liggins, R. T., & Burt, H. M. (2001) · International Journal of Pharmaceutics
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 122
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RNA-Seq Quantification of Hepatic Drug Processing Genes in Germ-Free Mice
Selwyn, F. P., Cui, J. Y., & Klaassen, C. D. (2015) · Drug Metabolism and Disposition
Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms
Cited by 122
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Curcumin relieved cisplatin-induced kidney inflammation through inhibiting Mincle-maintained M1 macrophage phenotype
Tan, R.-Z., Liu, J., Zhang, Y.-Y., Wang, H.-L., Li, J.-C., Liu, Y.-H., Zhong, X., Zhang, Y.-W., Yan, Y., Lan, H.-Y., et al. (2019) · Phytomedicine
Chemotherapy-induced organ toxicity mitigationAcute Kidney Injury Research
Cited by 122
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An Industrial Outbreak of Toxic Hepatitis Due to Methylenedianiline
McGill, D. B., & Motto, J. D. (1974) · New England Journal of Medicine
Drug-Induced Hepatotoxicity and ProtectionMedical Case Reports and Studies
Cited by 122
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Chronic antidepressants potentiate via sigma-1 receptors the brain-derived neurotrophic factor-induced signaling for glutamate release
Yagasaki, Y., Numakawa, T., Kumamaru, E., Hayashi, T., Su, T.-P., & Kunugi, H. (2006) · Journal of Biological Chemistry
Pharmacological Receptor Mechanisms and EffectsTreatment of Major Depression
Cited by 122
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Formulation and evaluation of metformin hydrochloride-loaded niosomes as controlled release drug delivery system
Hasan, A. A., Madkor, H., & Wageh, S. (2013) · Drug Delivery
Advanced Drug Delivery SystemsDrug Solubulity and Delivery Systems
Cited by 122
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Accuracy of Various Human NAT2 SNP Genotyping Panels to Infer Rapid, Intermediate and Slow Acetylator Phenotypes
Hein, D. W., & Doll, M. A. (2012) · Pharmacogenomics
Pharmacogenetics and Drug MetabolismGenetic Associations and Epidemiology
Cited by 121
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Absorption, metabolism and excretion of [14C]pomalidomide in humans following oral administration
Hoffmann, M., Kasserra, C., Reyes, J., Schafer, P., Kosek, J., Capone, L., Parton, A., Kim-Kang, H., Surapaneni, S., & Kumar, G. (2013) · Cancer Chemotherapy and Pharmacology
Pharmacogenetics and Drug MetabolismProtein Degradation and Inhibitors
Cited by 121
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The endogenous hallucinogen and trace amine N.N-dimethyltryptamine (DMT) displays potent protective effects against hypoxia via sigma-1 receptor activation in human primary iPSC-derived cortical neurons and microglia-like immune cells
Szabo, A., Kovacs, A., Riba, J., Djurovic, S., Rajnavolgyi, E., & Frecska, E. (2016) · Frontiers in Neuroscience
Pharmacological Receptor Mechanisms and EffectsPsychedelics and Drug Studies
Cited by 121
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Insect hormones. The structure of ponasterone A, insect-moulting hormone from the leaves of Podocarpus nakaii Hay
Nakanishi, K., Koreeda, M., Sasaki, S., Chang, M. L., & Hsu, H. Y. (1966) · Chemical Communications (London)
Bioactive natural compoundsBioactive Natural Diterpenoids Research
Cited by 121
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Regioselective hydroxylation of steroid hormones by human cytochromes P450
Niwa, T., Murayama, N., Imagawa, Y., & Yamazaki, H. (2015) · Drug Metabolism Reviews
Pharmacogenetics and Drug MetabolismSteroid Chemistry and Biochemistry
Cited by 121
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Extrapyramidal Symptoms Associated with Antidepressants—A Review of the Literature and An Analysis of Spontaneous Reports
Madhusoodanan, S., Alexeenko, L., Sanders, R., & Brenner, R. (2010) · Annals of Clinical Psychiatry
Pharmacovigilance and Adverse Drug ReactionsTreatment of Major Depression
Cited by 121
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Massively parallel variant characterization identifies NUDT15 alleles associated with thiopurine toxicity
Suiter, C. C., Moriyama, T., Matreyek, K. A., Yang, W., Scaletti, E. R., Nishii, R., Yang, W., Hoshitsuki, K., Singh, M., Trehan, A., et al. (2020) · Proceedings of the National Academy of Sciences
Pharmacogenetics and Drug MetabolismGenomics and Rare Diseases
Cited by 121
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Bioinformatics opportunities for identification and study of medicinal plants
Sharma, V., & Sarkar, I. N. (2013) · Briefings in Bioinformatics
Computational Drug Discovery MethodsEthnobotanical and Medicinal Plants Studies
Cited by 121
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GRcalculator: an online tool for calculating and mining dose–response data
Clark, N. A., Hafner, M., Kouril, M., Williams, E. H., Muhlich, J. L., Pilarczyk, M., Niepel, M., Sorger, P. K., & Medvedovic, M. (2017) · BMC Cancer
Computational Drug Discovery MethodsCell Image Analysis Techniques
Cited by 121
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In-silico Prediction of Synergistic Anti-Cancer Drug Combinations Using Multi-omics Data
Celebi, R., Bear Don’t Walk, O., Movva, R., Alpsoy, S., & Dumontier, M. (2019) · Scientific Reports
Computational Drug Discovery MethodsBioinformatics and Genomic Networks
Cited by 120
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Machine learning modeling of family wide enzyme-substrate specificity screens
Goldman, S., Das, R., Yang, K. K., & Coley, C. W. (2022) · PLOS Computational Biology
Computational Drug Discovery MethodsMachine Learning in Bioinformatics
Cited by 120
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