Most cited pharmacology, toxicology and pharmaceutics papers
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GENE EXPRESSION IN HUMAN HEPATOCYTES IN SUSPENSION AFTER ISOLATION IS SIMILAR TO THE LIVER OF ORIGIN, IS NOT AFFECTED BY HEPATOCYTE COLD STORAGE AND CRYOPRESERVATION, BUT IS STRONGLY CHANGED AFTER HEPATOCYTE PLATING
Richert, L., Liguori, M. J., Abadie, C., Heyd, B., Mantion, G., Halkic, N., & Waring, J. F. (2006) · Drug Metabolism and Disposition
Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology
Cited by 136
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M-cell targeted biodegradable PLGA nanoparticles for oral immunization against hepatitis B
Gupta, P. N., Khatri, K., Goyal, A. K., Mishra, N., & Vyas, S. P. (2007) · Journal of Drug Targeting
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 136
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Is dialysis a reliable method for studying drug release from nanoparticulate systems?—A case study
Zambito, Y., Pedreschi, E., & Di Colo, G. (2012) · International Journal of Pharmaceutics
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 136
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Isolation, characterization and antioxidative effect of phyllanthin against CCl4-induced toxicity in HepG2 cell line
Krithika, R., Mohankumar, R., Verma, R. J., Shrivastav, P. S., Mohamad, I. L., Gunasekaran, P., & Narasimhan, S. (2009) · Chemico-Biological Interactions
Phytochemistry and Bioactivity StudiesDrug-Induced Hepatotoxicity and Protection
Cited by 136
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Variability of CYP3A7 expression in human fetal liver
Leeder, J. S., Gaedigk, R., Marcucci, K. A., Gaedigk, A., Vyhlidal, C. A., Schindel, B. P., & Pearce, R. E. (2005) · The Journal of Pharmacology and Experimental Therapeutics
Pharmacogenetics and Drug MetabolismMetal-Catalyzed Oxygenation Mechanisms
Cited by 136
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Trials and tribulations of skin iontophoresis in therapeutics
Roustit, M., Blaise, S., & Cracowski, J. (2014) · British Journal of Clinical Pharmacology
Advancements in Transdermal Drug DeliveryAdvanced Drug Delivery Systems
Cited by 136
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Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects
Volpi, S., Bult, C. J., Chisholm, R. L., Deverka, P. A., Ginsburg, G. S., Jacob, H. J., Kasapi, M., McLeod, H. L., Roden, D. M., Williams, M. S., et al. (2018) · Clinical Pharmacology & Therapeutics
Pharmacogenetics and Drug MetabolismGenetic Associations and Epidemiology
Cited by 135
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Oral and Intravenous Acetylcysteine for Treatment of Acetaminophen Toxicity: A Systematic Review and Meta-analysis
Green, J., Heard, K., Reynolds, K., & Albert, D. (2013) · Western Journal of Emergency Medicine
Drug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments
Cited by 135
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Sex Differences in the Expression of Drug-Metabolizing and Transporter Genes in Human Liver
Yang, L., & Li, Y. (2012) · Journal of Drug Metabolism & Toxicology
Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms
Cited by 135
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Molecular Docking Screens Using Comparative Models of Proteins
Fan, H., Irwin, J. J., Webb, B. M., Klebe, G., Shoichet, B. K., & Sali, A. (2009) · Journal of Chemical Information and Modeling
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 135
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Pharmacokinetic comparison of sublingual lorazepam with intravenous, intramuscular, and oral lorazepam
Greenblatt, D. J., Divoll, M., Harmatz, J. S., & Shader, R. I. (1982) · Journal of Pharmaceutical Sciences
Pharmacogenetics and Drug MetabolismAnesthesia and Sedative Agents
Cited by 134
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Combination of argan oil and phospholipids for the development of an effective liposome-like formulation able to improve skin hydration and allantoin dermal delivery
Manca, M. L., Matricardi, P., Cencetti, C., Peris, J. E., Melis, V., Carbone, C., Escribano, E., Zaru, M., Fadda, A. M., & Manconi, M. (2016) · International Journal of Pharmaceutics
Advancements in Transdermal Drug DeliveryAdvanced Drug Delivery Systems
Cited by 134
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Post-Marketing Safety Concerns with Esketamine: A Disproportionality Analysis of Spontaneous Reports Submitted to the FDA Adverse Event Reporting System
Gastaldon, C., Raschi, E., Kane, J. M., Barbui, C., & Schoretsanitis, G. (2021) · Psychotherapy and Psychosomatics
Pharmacovigilance and Adverse Drug ReactionsTreatment of Major Depression
Cited by 134
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Development of proteo-chemometrics: a novel technology for the analysis of drug-receptor interactions
Lapinsh, M., Prusis, P., Gutcaits, A., Lundstedt, T., & Wikberg, J. E. S. (2001) · Biochimica et Biophysica Acta (BBA) - General Subjects
Computational Drug Discovery MethodsReceptor Mechanisms and Signaling
Cited by 134
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Developing a Multi-Dose Computational Model for Drug-Induced Hepatotoxicity Prediction Based on Toxicogenomics Data
Su, R., Wu, H., Xu, B., Liu, X., & Wei, L. (2019) · IEEE/ACM Transactions on Computational Biology and Bioinformatics
Drug-Induced Hepatotoxicity and ProtectionComputational Drug Discovery Methods
Cited by 134
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Poly(ethylene glycol) as stabilizer and emulsifying agent: a novel stabilization approach preventing aggregation and inactivation of proteins upon encapsulation in bioerodible polyester microspheres
Castellanos, I. (2003) · Journal of Controlled Release
Advanced Drug Delivery SystemsProteins in Food Systems
Cited by 134
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CovalentDock: Automated covalent docking with parameterized covalent linkage energy estimation and molecular geometry constraints
Ouyang, X., Zhou, S., Su, C. T. T., Ge, Z., Li, R., & Kwoh, C. K. (2013) · Journal of Computational Chemistry
Computational Drug Discovery MethodsCholinesterase and Neurodegenerative Diseases
Cited by 134
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Parallel Optimization of Synthetic Pathways within the Network of Organic Chemistry
Kowalik, M., Gothard, C. M., Drews, A. M., Gothard, N. A., Weckiewicz, A., Fuller, P. E., Grzybowski, B. A., & Bishop, K. J. M. (2012) · Angewandte Chemie International Edition
Computational Drug Discovery MethodsMicrobial Metabolic Engineering and Bioproduction
Cited by 134
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A learning-based method for drug-target interaction prediction based on feature representation learning and deep neural network
Peng, J., Li, J., & Shang, X. (2020) · BMC Bioinformatics
Computational Drug Discovery MethodsBioinformatics and Genomic Networks
Cited by 133
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PON1 and Neurodevelopment in Children from the CHAMACOS Study Exposed to Organophosphate Pesticides in Utero
Eskenazi, B., Huen, K., Marks, A., Harley, K. G., Bradman, A., Barr, D. B., & Holland, N. (2010) · Environmental Health Perspectives
Pesticide Exposure and ToxicityParaoxonase enzyme and polymorphisms
Cited by 133
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Small‐molecule protein–protein interaction inhibitors: Therapeutic potential in light of molecular size, chemical space, and ligand binding efficiency considerations
Buchwald, P. (2010) · IUBMB Life
Computational Drug Discovery MethodsChemical Synthesis and Analysis
Cited by 133
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Alarms about structural alerts
Alves, V. M., Muratov, E. N., Capuzzi, S. J., Politi, R., Low, Y., Braga, R. C., Zakharov, A. V., Sedykh, A., Mokshyna, E., Farag, S., et al. (2016) · Green Chemistry
Computational Drug Discovery MethodsEnvironmental Toxicology and Ecotoxicology
Cited by 133
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CSAR benchmark exercise 2011–2012: evaluation of results from docking and relative ranking of blinded congeneric series.
Damm-Ganamet, K. L., Smith, R. D., Dunbar, J. B., Stuckey, J. A., & Carlson, H. A. (2013) · Journal of Chemical Information and Modeling
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 133
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DeepDrug3D: Classification of ligand-binding pockets in proteins with a convolutional neural network
Pu, L., Govindaraj, R. G., Lemoine, J. M., Wu, H.-C., & Brylinski, M. (2019) · PLOS Computational Biology
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 133
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