Cited by 161Adrenal and Paraganglionic TumorsHormonal Regulation and HypertensionAdrenal Hormones and Disorders

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SMALL ADENOMAS OF THE ADRENAL CORTEX IN HYPERTENSION AND DIABETES

RUSSI, SIMON·1945·Archives of Internal Medicine

DOI 10.1001/archinte.1945.00210350030005

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Abstract

The principal observations generally reported concerning persons with tumors of the adrenal cortex consist of obesity, purple striae of the skin, acne, polycythemia,is, imbalanceplasma electrolytes, diabetes, hypertension genital dystrophy. These signs and symptoms have been observed in persons with adenohyperplasiasin those with carcinomas of the adrenal cortex, and the total picture is usually referred to as Cushing's disease or adrenogenital syndrome. In general, even the benign tumors which produce this clinical entity occupy a large portion of the adrenal gland. There are, in addition, as Kepler and Keating 1 pointed out, a large number of small cortical adenomasre encountereddentally in the course of routine autopsiespersons in whom there was no apparent clinical evidence of endocrine disease during life. The investigations presented here were undertaken in order to determine whether or not an examination of the clinical and pathologic data, in retrospect, would show the presence of certain endocrinologie disturbances not noted during the

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Authors: RUSSI, S.
Corresponding author: RUSSI, SIMON
Venue: Archives of Internal Medicine
Publisher: American Medical Association (AMA)
Published: 1945-11-01
Volume: 76
Issue: 5
Pages: 284
ISSN: 0003-9926 (ISSN-L)
DOI: 10.1001/archinte.1945.00210350030005
OpenAlex: W2074901715
Cited by: 161
References: 21
Citations by year: 2026: 1 · 2025: 1 · 2024: 1 · 2022: 2 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 3 · 2014: 3 · 2013: 2 · 2012: 1
FWCI: 7.49
Type: journal article
Language: en
Open access: closed
Locations: Archives of Internal Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords: adrenal adenoma, hypertension, diabetes mellitus, Cushing's disease, adrenogenital syndrome, endocrine disorders, autopsy findings, adrenal hyperplasia
MeSH terms: Adenoma, Adrenal Cortex, Adrenal Gland Neoplasms, Adrenal Glands, Blood Pressure, Diabetes Mellitus, Humans, Hypertension, Neoplasms

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SMALL ADENOMAS OF THE ADRENAL CORTEX IN HYPERTENSION AND DIABETES

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