Cited by 549Attention Deficit Hyperactivity DisorderChild and Adolescent Psychosocial and Emotional DevelopmentPsychopathy, Forensic Psychiatry, Sexual Offending

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Hyperactive Boys Almost Grown Up: V. Replication of Psychiatric Status

Mannuzza, Salvatore·1991·Archives of General Psychiatry

DOI 10.1001/archpsyc.1991.01810250079012

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Abstract

We previously reported a prospective follow-up study of 101 young adult males whose conditions had been diagnosed as hyperactivity in childhood. Compared with controls, probands had significantly higher rates of attention-deficit, antisocial, and drug use disorders at follow-up (mean age, 18 years). The present study was an attempt to replicate these findings on an independent sample of 94 hyperactive boys who were seen at the same clinic, compared with 78 normal controls. Assessments were made by clinicians who were blind to group membership. Information was obtained for 90% of the original cohort. As in the previous study, significantly more probands than controls were given ongoing diagnoses of attention-deficit disorder (43% vs 4%), antisocial disorders (32% vs 8%), and drug use disorders (10% vs 1%). Furthermore, the absolute rates of these disorders were comparable for corresponding groups across studies, and the adjusted odds ratios did not differ significantly. As previously, there was no increased risk for affective disorders in the grown hyperactive children. The present study provides a powerful replication of the nature of the young adult outcome of childhood hyperactivity.

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Hyperactive Boys Almost Grown Up: I. Psychiatric Status
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Result
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Method
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“The percentage of children who retain the diagnosis into adulthood varies across studies from 30% to 60% according to the criteria used to assess ADHD symptoms in the adult population [Barkley et al., 1990; Mannuzza et al., 1991; Weiss et al., 2000].”
Background
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Uso de un cuestionario breve para el diagnóstico de deficiencia atencional
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Explanatory Models of ADHD
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“, 1996; Slomkowski, Klein, & Mannuzza, 1995), and investigators have indicated that problems due to ADHD are not just transient phenomena, but can adversely affect the developmental path of affected youngsters, resulting in impaired adult productivity and well-being (Mannuzza, Klein, Bessler, Malloy, & LaPadula, 1993;…”
Background
The role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and attention-deficit/hyperactivity disorder
Sukhodolsky, D. G., Leckman, J. F., Rothenberger, A., & Scahill, L. D. (2007) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-007-1007-3 · Cited by 49
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“Once considered a childhood disease, it is now known that approximately 40% to 70% of children with ADHD will have symptoms persist into adolescence and adulthood.(3,4) ADHD is characterized by various symptoms of inattention and/or hyperactivity and impulsivity.”
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“(Gittelman et al., 1985; Mannuzza et al. 1991, 1993; Hechtman, 1992).”
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“The evidence for this association comes from crosssectional (Molina, Smith, & Pelham, 1999) and prospective studies (Mannuzza et al., 1991) demonstrating higher rates of illicit substance use (ISU) and/or substance use disorders (SUDs) in individuals with ADHD.”
Background
Detection of malingered attention deficit hyperactivity disorder
Tucha, L., Sontag, T. A., Walitza, S., & Lange, K. W. (2009) · ADHD Attention Deficit and Hyperactivity Disorders · doi:10.1007/s12402-009-0007-1 · Cited by 37
A transmission disequilibrium test of the Ser9/Gly dopamine D3 receptor gene polymorphism in adult attention-deficit hyperactivity disorder
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The Neuroscience of Adolescence
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Hyperactivity-inattention symptoms in childhood and substance use in adolescence: The youth gazel cohort
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Authors: Mannuzza, S.
Affiliations: Long Island Jewish Medical Center (US)
Corresponding author: Mannuzza, Salvatore
Venue: Archives of General Psychiatry
Publisher: American Medical Association (AMA)
Published: 1991-01-01
Volume: 48
Issue: 1
Pages: 77
ISSN: 0003-990X (ISSN-L)
DOI: 10.1001/archpsyc.1991.01810250079012
OpenAlex: W2108483316
Cited by: 549
References: 0
Citations by year: 2026: 2 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 6 · 2019: 3 · 2018: 5 · 2017: 3 · 2016: 4 · 2015: 12 · 2014: 16 · 2013: 18 · 2012: 21
FWCI: 14.99
Type: journal article
Language: en
Open access: closed
Locations: Archives of General Psychiatry (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Mental Health (MH-18579, R01MH018579, MH30906)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
Keywords: hyperactive children, adult outcomes, attention deficit disorder, antisocial personality disorder, drug use disorders, mood disorders, replication study, young men, long-term follow-up
MeSH terms: Adolescent, Age Factors, Alcoholism, Antisocial Personality Disorder, Attention Deficit Disorder with Hyperactivity, Mental Disorders, Child, Child Behavior Disorders, Child, Preschool, Female, Follow-Up Studies, Humans, Infant, Male, Psychiatric Status Rating Scales, Psychometrics, Regression Analysis, Comorbidity, Prevalence, Substance-Related Disorders

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Hyperactive Boys Almost Grown Up: V. Replication of Psychiatric Status

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