UKPDS 26: sulphonylurea failure in non-insulin-dependent diabetic patients over six years
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In the UKPDS cohort of subjects with recently diagnosed Type 2 diabetes, there is an ongoing decline in beta-cell function without a change in insulin sensitivity.
“in this cohort of subjects with recently diagnosed Type 2 diabetes, an ongoing decline in beta-cell function without a change in insulin sensitivity was occurring [17, 18].”
From The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes (2003) · cites this paper as [17]
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- Authors
- UK Prospective Diabetes Study (UKPDS) Group, Matthews, D. R., Cull, C. A., Stratton, I. M., Holman, R. R., & Turner, R. C.
- Venue
- Diabetic Medicine
- Published
- 1998
- References
- 0
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