The DOI matches its Crossref record; 640 of the 645 references it cites were found in a registry or an index.
Interventions for enhancing medication adherence
Open accessAbstract
BACKGROUND: People who are prescribed self administered medications typically take only about half their prescribed doses. Efforts to assist patients with adherence to medications might improve the benefits of prescribed medications. OBJECTIVES: The primary objective of this review is to assess the effects of interventions intended to enhance patient adherence to prescribed medications for medical conditions, on both medication adherence and clinical outcomes. SEARCH METHODS: We updated searches of The Cochrane Library, including CENTRAL (via http://onlinelibrary.wiley.com/cochranelibrary/search/), MEDLINE, EMBASE, PsycINFO (all via Ovid), CINAHL (via EBSCO), and Sociological Abstracts (via ProQuest) on 11 January 2013 with no language restriction. We also reviewed bibliographies in articles on patient adherence, and contacted authors of relevant original and review articles. SELECTION CRITERIA: We included unconfounded RCTs of interventions to improve adherence with prescribed medications, measuring both medication adherence and clinical outcome, with at least 80% follow-up of each group studied and, for long-term treatments, at least six months follow-up for studies with positive findings at earlier time points. DATA COLLECTION AND ANALYSIS: Two review authors independently extracted all data and a third author resolved disagreements. The studies differed widely according to medical condition, patient population, intervention, measures of adherence, and clinical outcomes. Pooling results according to one of these characteristics still leaves highly heterogeneous groups, and we could not justify meta-analysis. Instead, we conducted a qualitative analysis with a focus on the RCTs with the lowest risk of bias for study design and the primary clinical outcome. MAIN RESULTS: The present update included 109 new RCTs published since the previous update in January 2007, bringing the total number of RCTs to 182; we found five RCTs from the previous update to be ineligible and excluded them. Studies were heterogeneous for patients, medical problems, treatment regimens, adherence interventions, and adherence and clinical outcome measurements, and most had high risk of bias. The main changes in comparison with the previous update include that we now: 1) report a lack of convincing evidence also specifically among the studies with the lowest risk of bias; 2) do not try to classify studies according to intervention type any more, due to the large heterogeneity; 3) make our database available for collaboration on sub-analyses, in acknowledgement of the need to make collective advancement in this difficult field of research. Of all 182 RCTs, 17 had the lowest risk of bias for study design features and their primary clinical outcome, 11 from the present update and six from the previous update. The RCTs at lowest risk of bias generally involved complex interventions with multiple components, trying to overcome barriers to adherence by means of tailored ongoing support from allied health professionals such as pharmacists, who often delivered intense education, counseling (including motivational interviewing or cognitive behavioral therapy by professionals) or daily treatment support (or both), and sometimes additional support from family or peers. Only five of these RCTs reported improvements in both adherence and clinical outcomes, and no common intervention characteristics were apparent. Even the most effective interventions did not lead to large improvements in adherence or clinical outcomes. AUTHORS' CONCLUSIONS: Across the body of evidence, effects were inconsistent from study to study, and only a minority of lowest risk of bias RCTs improved both adherence and clinical outcomes. Current methods of improving medication adherence for chronic health problems are mostly complex and not very effective, so that the full benefits of treatment cannot be realized. The research in this field needs advances, including improved design of feasible long-term interventions, objective adherence measures, and sufficient study power to detect improvements in patient-important clinical outcomes. By making our comprehensive database available for sharing we hope to contribute to achieving these advances.
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In the citing paper
“Although there is a wealth of controlled trials on interventions to improve adherence, current methods of improving medication adherence for chronic health problems are mostly complex and not effective [2,3,4].”
From Factors Contributing to Medication Adherence in Patients with a Chronic Condition: A Scoping Review of Qualitative Research (2021) · cites this paper as [3]
In the citing paper
“This review is in agreement with other, CF-related reviews and general adherence reviews, which have highlighted the limitations of many included trials in terms of having small sample sizes and being underpowered to detect a meaningful difference in adherence (Goldbeck 2014; Nieuwlaat 2014).”
From Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis (2023) · cites this paper as Nieuwlaat 2014
In the citing paper
“Previous Cochrane Reviews on adherence (Nieuwlaat 2014) and CF-specific reviews (Goldbeck 2014; Savage 2014) have not used a coding framework, so this review has improved on existing methodologies.”
From Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis (2023) · cites this paper as Nieuwlaat 2014
In the citing paper
“Given the complexity of many adherence interventions tested to date (Nieuwlaat 2014), and the way in which complex interventions are reported or described in the literature, it is o en difficult to determine the content, or the 'active ingredients', of effective interventions that bring about change (Michie 2009).”
From Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis (2023) · cites this paper as Nieuwlaat 2014
In the citing paper
“Understanding the 'active ingredients' of promising interventions will make it easier to replicate effective interventions; will reduce the potential waste of time and resources on trials of ineffective techniques (Michie 2009); and will inform adherence research in the future (Nieuwlaat 2014).”
From Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis (2023) · cites this paper as Nieuwlaat 2014
In the citing paper
“A previous Cochrane Review highlighted likely inclusion bias in adherence trials, with participants having higher than average adherence at baseline (Nieuwlaat 2014).”
From Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis (2023) · cites this paper as Nieuwlaat 2014
In the citing paper
“Underpowered trials are more likely to miss a meaningful difference in adherence, even when improving adherence substantially, and showing an effect on clinical outcomes is likely even harder (Nieuwlaat 2014).”
From Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis (2023) · cites this paper as Nieuwlaat 2014
In the citing paper
“Interventions that specifically aim to improve adherence to prescribed medications vary widely (Nieuwlaat 2014).”
From Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis (2023) · cites this paper as Nieuwlaat 2014
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Items 201–400 of 640
Hyder, S. M. Z., Persson, L. Å., Chowdhury, R., & Ekström, E. (2002) · PubMed · Cited by 138
de Bruin, M., Hospers, H. J., van Breukelen, G., Kok, G., Koevoets, W. M., & Prins, J. M. (2010) · Health Psychology · doi:10.1037/a0020335 · Cited by 136
DeJesus, E., Young, B., Morales-Ramirez, J. O., Sloan, L. M., Ward, D. J., Flaherty, J. F., Ebrahimi, R., Maa, J., Reilly, K., Ecker, J., et al. (2009) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e3181a572cf · Cited by 135
Penicillin V for Group A Streptococcal Pharyngotonsillitis
Schwartz, R. H. (1981) · JAMA · doi:10.1001/jama.1981.03320160022023 · Cited by 135
Bonner, S., Zimmerman, B. J., Evans, D. J., Irigoyen, M., Resnick, D. J., & Mellins, R. B. (2002) · Journal of Asthma · doi:10.1081/jas-120002198 · Cited by 133
Seal, K. (2003) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(03)00074-7 · Cited by 133
Adherence Feedback to Improve Asthma Outcomes Among Inner-City Children: A Randomized Trial
Otsuki, M., Eakin, M. N., Rand, C. S., Butz, A. M., Hsu, V. D., Zuckerman, I. H., Ogborn, J., Bilderback, A. L., & Riekert, K. A. (2009) · PEDIATRICS · doi:10.1542/peds.2008-2961 · Cited by 132
Feinstein, A. R., Wood, H. F., Epstein, J. A., Taranta, A., Simpson, R., Tursky, E., Argyros, T. G., Frieden, J. H., Haas, R. C., Hirschfeld, I., et al. (1959) · New England Journal of Medicine · doi:10.1056/nejm195904022601405 · Cited by 132
Effectiveness of Collaborative Care for Depression in Human Immunodeficiency Virus Clinics
Pyne, J. M., Fortney, J. C., Curran, G. M., Tripathi, S., Atkinson, J. H., Kilbourne, A. M., Hagedorn, H. J., Rimland, D., Rodriguez-Barradas, M. C., Monson, T., et al. (2010) · Archives of Internal Medicine · doi:10.1001/archinternmed.2010.395 · Cited by 132
Pradier, C., Laurence, B. L., Spire, B., Tourette-Turgis, C., Michel, M., Souville, M., Rébillon, M., Jean-Gabriel, F., Pesce, A., Dellamonica, P., et al. (2003) · HIV Clinical Trials · doi:10.1310/brbv-3941-h1pp-ndry · Cited by 131
Brus, H. L. M., van de Laar, M. A. F. J., Taal, E., Rasker, J. J., & Wiegman, O. (1998) · Annals of the Rheumatic Diseases · doi:10.1136/ard.57.3.146 · Cited by 131
Using Motivational Interviewing to Promote Adherence to Antiretroviral Medications: A Pilot Study
DiIorio, C. K., Resnicow, K., McDonnell, M., Soet, J. E., McCarty, F., & Yeager, K. A. (2003) · Journal of the Association of Nurses in AIDS Care · doi:10.1177/1055329002250996 · Cited by 129
Electronic monitoring and counseling to improve medication adherence
Rosen, M. I., Rigsby, M. O., Salahi, J. T., Ryan, C. E., & Cramer, J. A. (2003) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(03)00149-9 · Cited by 129
Pearson, C. R., Micek, M. A., Simoni, J. M., Hoff, P. D., Matediana, E., Martin, D. P., & Gloyd, S. S. (2007) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e318153f7ba · Cited by 129
Randomized Trial of Depression Follow-Up Care by Online Messaging
Simon, G. E., Ralston, J. D., Savarino, J. E., Pabiniak, C. J., Wentzel, C., & Operskalski, B. H. (2011) · Journal of General Internal Medicine · doi:10.1007/s11606-011-1679-8 · Cited by 127
Jiang, X., Sit, J. W. H., & Wong, T. K. (2007) · Journal of Clinical Nursing · doi:10.1111/j.1365-2702.2007.01838.x · Cited by 127
Caring for Poorly Controlled Diabetes Mellitus: A Randomized Pharmacist Intervention
Odegard, P. S., Goo, A., Hummel, J., Williams, K. L., & Gray, S. L. (2005) · Annals of Pharmacotherapy · doi:10.1345/aph.1e438 · Cited by 126
A critical review of interventions to improve compliance with prescribed medications
Haynes, R. B., Wang, E., & Gomes, M. D. M. (1987) · Patient Education and Counseling · doi:10.1016/0738-3991(87)90095-4 · Cited by 126
Self-citationSamet, J. H., Horton, N. J., Meli, S. M., Dukes, K., Tripp, T. J., SULLIVAN, L. M., & Freedberg, K. A. (2005) · Antiviral Therapy · doi:10.1177/135965350501000106 · Cited by 125
Simmons, S. F., Alessi, C., & Schnelle, J. F. (2001) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2001.49183.x · Cited by 125
Chien, W. T., Chan, S. W., & Thompson, D. R. (2006) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.105.008375 · Cited by 125
Barbanel, D. (2003) · Thorax · doi:10.1136/thorax.58.10.851 · Cited by 125
Psychodynamic psychotherapy and clomipramine in the treatment of major depression.
Burnand, Y., Andreoli, A., Kolatte, E., Venturini, A., & Rosset, N. (2002) · Psychiatric Services · doi:10.1176/appi.ps.53.5.585 · Cited by 125
Pharmaceutical Care Research and Education Project: Patient Outcomes
Volume, C. I., Farris, K. B., Kassam, R., Cox, C. E., & Cave, A. (2001) · Journal of the American Pharmaceutical Association (1996) · doi:10.1016/s1086-5802(16)31255-4 · Cited by 125
Improving primary care in rural Alabama with a pharmacy initiative
Taylor, C. T., Byrd, D. C., & Krueger, K. P. (2003) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/60.11.1123 · Cited by 123
Penicillin Treatment of Streptococcal Pharyngitis
Colcher, I. S. (1972) · JAMA · doi:10.1001/jama.1972.03210060015003 · Cited by 123
Impact of pharmaceutical care on health outcomes in patients with COPD
Jarab, A. S., Alqudah, S., Khdour, M. R., Shamssain, M., & Mukattash, T. L. (2011) · International Journal of Clinical Pharmacy · doi:10.1007/s11096-011-9585-z · Cited by 123
A medication self-management program to improve adherence to HIV therapy regimens
Smith, S. R., Rublein, J. C., Marcus, C., Brock, T. P., & Chesney, M. A. (2003) · Patient Education and Counseling · doi:10.1016/s0738-3991(02)00127-1 · Cited by 123
Merinder, L. B., Viuff, A. G., Laugesen, H., Clemmensen, K., Misfelt, S., & Espensen, B. (1999) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s001270050146 · Cited by 123
DOES ENCOURAGING GOOD COMPLIANCE IMPROVE PATIENTS' CLINICAL CONDITION IN HEART FAILURE?
Goodyer, L., Miskelly, F. G., & Milligan, P. J. (1995) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.1995.tb09942.x · Cited by 122
Leenen, F. H. H., Wilson, T. W., Bolli, P., Larochelle, P. M., Myers, M. G., Handa, S., Boileau, G., & Tanner, J. (1997) · PubMed · Cited by 121
Purcell, D. W., Latka, M. H., Metsch, L. R., Latkin, C. A., Gomez, C. A., Mizuno, Y., Arnsten, J. H., Wilkinson, J. D., Knight, K. R., Knowlton, A. R., et al. (2007) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e31815767c4 · Cited by 121
Andrade, A. S., McGruder, H. F., Wu, A. W., Celano, S. A., Skolasky, R. L., Selnes, O. A., Huang, I., & McArthur, J. C. (2005) · Clinical Infectious Diseases · doi:10.1086/432877 · Cited by 121
A study of a multi-level intervention to improve non-adherence in difficult to control asthma
Gamble, J., Stevenson, M., & Heaney, L. G. (2011) · Respiratory Medicine · doi:10.1016/j.rmed.2011.03.019 · Cited by 120
Ting, T. V., Kudalkar, D., Nelson, S. M., Cortina, S., Pendl, J. D., Budhani, S., NEVILLE, J., Taylor, J., Huggins, J., Drotar, D., et al. (2011) · The Journal of Rheumatology · doi:10.3899/jrheum.110771 · Cited by 120
Effects of computer generated reminder charts on patients' compliance with drug regimens.
Raynor, D. K., Booth, T. G., & Blenkinsopp, A. (1993) · BMJ · doi:10.1136/bmj.306.6886.1158 · Cited by 119
Self-recording of blood pressure in the management of hypertension.
Johnson, A. L., Taylor, D. W., Sackett, D. L., Dunnett, C. W., & Shimizu, A. (1978) · PubMed Central · Cited by 118
Gwadry-Sridhar, F. H., Arnold, J. M. O., Zhang, Y., Brown, J. E., Marchiori, G. E., & Guyatt, G. H. (2005) · American Heart Journal · doi:10.1016/j.ahj.2005.08.016 · Cited by 118
Ngoh, L. N., & Shepherd, M. D. (1997) · Patient Education and Counseling · doi:10.1016/s0738-3991(96)00976-7 · Cited by 117
The Community Pharmacy Medicines Management Project Evaluation Team (2007) · Family Practice · doi:10.1093/fampra/cml075 · Cited by 116
Ponnusankar, S., Mallayasamy, S., Anandamoorthy, N., & Suresh, B. (2003) · Patient Education and Counseling · doi:10.1016/s0738-3991(03)00193-9 · Cited by 115
Treiber, G., Wittig, J., Ammon, S., Walker, S., van Doorn, L., & Klotz, U. E. (2002) · Archives of Internal Medicine · doi:10.1001/archinte.162.2.153 · Cited by 115
Direct clinician-to-patient feedback discussion of inhaled steroid use: its effect on adherence
Onyirimba, F., Apter, A. J., Reisine, S., Litt, M. D., McCusker, C., Connors, M., & ZuWallack, R. (2003) · Annals of Allergy Asthma & Immunology · doi:10.1016/s1081-1206(10)61825-x · Cited by 115
Márquez Contreras, E., de la Figuera von Wichmann, M., Gil Guillén, V., Ylla-Catalá, A., Figueras, M., Balaña, M., & Naval, J. (2004) · Atención Primaria · doi:10.1016/s0212-6567(04)78922-2 · Cited by 115
Treatment adherence therapy in people with psychotic disorders: randomised controlled trial
Staring, A. B. P., van der Gaag, M., Koopmans, G. T., Selten, J., Beveren, J. M. V., Hengeveld, M. W., LOONEN, A. J. M., & Mulder, C. L. (2010) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.110.077289 · Cited by 115
Information, compliance and side‐effects: a study of patients on antidepressant medication.
Myers, E. D., & Calvert, E. J. (1984) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1984.tb04993.x · Cited by 114
Comparing compliance patterns between randomized treatments
Vrijens, B., & Goetghebeur, E. (1997) · Controlled Clinical Trials · doi:10.1016/s0197-2456(96)00235-8 · Cited by 114
Windsor, R. A., Bailey, W. C., Richards, J. M., Manzella, B. A., Soong, S.-J., & Brooks, M. (1990) · American Journal of Public Health · doi:10.2105/ajph.80.12.1519 · Cited by 114
Pharmaceutical care of patients with heart failure
Sadik, A., Yousif, M. A., & McElnay, J. C. (2005) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2005.02387.x · Cited by 114
Duncan, L. G., Moskowitz, J. T., Neilands, T. B., Dilworth, S. E., Hecht, F. M., & Johnson, M. O. (2011) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2011.04.007 · Cited by 114
Sclar, D. A., Chin, A., Skaer, T. L., Okamoto, M. P., Nakahiro, R. K., & Gill, M. A. (1991) · PubMed · Cited by 113
Ansah, E. K., Gyapong, J. O., Agyepong, I. A., & Evans, D. B. (2001) · Tropical Medicine & International Health · doi:10.1046/j.1365-3156.2001.00740.x · Cited by 113
Enhancing cancer pain control regimens through patient education
Rimer, B. K., Levy, M., Keintz, M. K., Fox, L., Engstrom, P. F., & MacElwee, N. (1987) · Patient Education and Counseling · doi:10.1016/0738-3991(87)90128-5 · Cited by 112
Community pharmacy based provision of pharmaceutical care to older patients.
Sturgess, I., McElnay, J. C., Hughes, C. M., & Crealey, G. (2003) · Pharmacy World & Science · doi:10.1023/a:1025860402256 · Cited by 111
Compliance with antiretroviral regimens to prevent perinatal HIV-1 transmission in Kenya
Kiarie, J. N., Kreiss, J. K., Richardson, B. A., & John-Stewart, G. C. (2003) · AIDS · doi:10.1097/00002030-200301030-00009 · Cited by 111
Osteoporosis Telephonic Intervention to Improve Medication Regimen Adherence
Solomon, D. H. (2012) · Archives of Internal Medicine · doi:10.1001/archinternmed.2011.1977 · Cited by 111
Use of an on-line pager system to increase adherence to antiretroviral medications
Safren, S. A., Hendriksen, E. S., Desousa, N., Boswell, S. L., & Mayer, K. H. (2003) · AIDS Care · doi:10.1080/09540120310001618630 · Cited by 110
Pladevall, M., Brotons, C., Gabriel, R., Arnau, A., Suárez, C., de la Figuera, M., Marquez, E., Coca, A., Sobrino, J., Divine, G., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.892778 · Cited by 109
Allen, J. K., Blumenthal, R. S., Margolis, S., Young, D. R., Miller, E. R., & Kelly, K. J. (2002) · American Heart Journal · doi:10.1067/mhj.2002.124837 · Cited by 109
Randomized trial of lottery-based incentives to improve warfarin adherence
Kimmel, S. E., Troxel, A. B., Loewenstein, G. F., Brensinger, C. M., Jaskowiak, J., Doshi, J. A., Laskin, M. S., & Volpp, K. G. M. (2012) · American Heart Journal · doi:10.1016/j.ahj.2012.05.005 · Cited by 109
Chung, M. H., Richardson, B. A., Tapia, K., Benki-Nugent, S., Kiarie, J. N., Simoni, J. M., Overbaugh, J., Attwa, M., & John-Stewart, G. C. (2011) · PLoS Medicine · doi:10.1371/journal.pmed.1000422 · Cited by 109
de Bruin, M., Hospers, H. J., van den Borne, H. W., Kok, G., & Prins, J. M. (2005) · AIDS Patient Care and STDs · doi:10.1089/apc.2005.19.384 · Cited by 108
Chaisson, R. E., Barnes, G. L., Hackman, J., Watkinson, L., Lucree Kimbrough, L. P. N., Metha, S. D., Cavalcante, S. C., & Moore, R. D. (2001) · The American Journal of Medicine · doi:10.1016/s0002-9343(01)00695-7 · Cited by 108
Gustafson, D. H., Wise, M. E., Bhattacharya, A., Pulvermacher, A., Shanovich, K., Phillips, B. R., Lehman, E. B., Chinchilli, V. M., Hawkins, R. P., & Kim, J.-S. (2012) · Journal of Medical Internet Research · doi:10.2196/jmir.1964 · Cited by 108
Sustained Benefit From a Long-Term Antiretroviral Adherence Intervention
Mannheimer, S., Morse, E. V., Matts, J. P., Andrews, L., Child, C. C., Schmetter, B., & FRIEDLAND, G. H. (2006) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/01.qai.0000245887.58886.ac · Cited by 107
Pharmacist Telemonitoring of Antidepressant Use: Effects on Pharmacist–Patient Collaboration
Rickles, N. M., Svarstad, B. L., Statz-Paynter, J. L., Taylor, L. V. H., & Kobak, K. A. (2005) · Journal of the American Pharmacists Association · doi:10.1331/1544345054003732 · Cited by 105
Baker, R., Reddish, S., Robertson, N., Hearnshaw, H., & Jones, B. (2001) · Europe PMC (PubMed Central) · Cited by 105
Sabin, L., DeSilva, M. B., Hamer, D. H., Xu, K., Zhang, J., Li, T., Wilson, I. B., & Gill, C. J. (2009) · AIDS and Behavior · doi:10.1007/s10461-009-9615-1 · Cited by 104
Obreli-Neto, P. R., Guidoni, C. M., Baldoni, A. O., Pilger, D. A., Cruciol-Souza, J. M., Gaeti, W. P., & Cuman, R. K. N. (2011) · International Journal of Clinical Pharmacy · doi:10.1007/s11096-011-9518-x · Cited by 103
A Randomised Trial of Strategies to Improve Patient Compliance with Anticonvulsant Therapy
Peterson, G. M., McLean, S., & Millingen, K. S. (1984) · Epilepsia · doi:10.1111/j.1528-1157.1984.tb03436.x · Cited by 103
Health Coaching to Improve Hypertension Treatment in a Low-Income, Minority Population
Margolius, D., Bodenheimer, T., Bennett, H., Wong, J. S., Ngo, V., Padilla, G., & Thom, D. H. (2012) · The Annals of Family Medicine · doi:10.1370/afm.1369 · Cited by 103
Effects of a School-based Intervention for Urban Adolescents with Asthma: A Controlled Trial
Bruzzese, J., Sheares, B. J., Vincent, E. J., Du, Y. E., Sadeghi, H., Levison, M. J., Mellins, R. B., & Evans, D. (2010) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201003-0429oc · Cited by 102
A Controlled Evaluation of Psychoeducational Family Intervention in a Rural Chinese Community
Xiang, M., Ran, M., & Li, S. (1994) · British Journal of Psychiatry · doi:10.1192/bjp.165.4.544 · Cited by 102
The effects of patient education in COPD in a 1-year follow-up randomised, controlled trial
Gallefoss, F. (2003) · Patient Education and Counseling · doi:10.1016/s0738-3991(03)00100-9 · Cited by 102
Rathbun, R. C., Farmer, K. C., Stephens, J. R., & Lockhart, S. M. (2005) · Clinical Therapeutics · doi:10.1016/j.clinthera.2005.02.010 · Cited by 102
Brown, B. G., Bardsley, J., Poulin, D., Hillger, L. A., Dowdy, A. A., Maher, V. M. G., Zhao, X.-Q., Albers, J. J., & Knopp, R. H. (1997) · The American Journal of Cardiology · doi:10.1016/s0002-9149(97)00303-2 · Cited by 102
Two-year effects of quality improvement programs on medication management for depression
Unützer, J., Rubenstein, L., Katon, W. J., Tang, L., Duan, N., Lagomasino, I. T., & Wells, K. B. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.10.935 · Cited by 102
Riis, B. J., Ise, J., Stein, T. V., Bagger, Y. Z., & Christiansen, C. (2001) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2001.16.10.1871 · Cited by 100
Berg, K. M., Litwin, A. H., Li, X., Heo, M., & Arnsten, J. H. (2010) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2010.07.025 · Cited by 100
Effects of future writing and optimism on health behaviors in HIV-infected women
Mann, T. L. (2001) · Annals of Behavioral Medicine · doi:10.1207/s15324796abm2301_5 · Cited by 99
for the LifeWindows Team, Fisher, J. D., Amico, K. R., Fisher, W. A., Cornman, D. H., Shuper, P. A., Trayling, C., Redding, C. G., Barta, W. D., Lemieux, A. F., et al. (2011) · AIDS and Behavior · doi:10.1007/s10461-011-9926-x · Cited by 99
Birtwhistle, R. (2004) · BMJ · doi:10.1136/bmj.37967.374063.ee · Cited by 99
Martins, N., Morris, P. S., & Kelly, P. M. (2009) · BMJ · doi:10.1136/bmj.b4248 · Cited by 99
A Randomized Study of the Effects of a Home Diabetes Education Program
Rettig, B., Dg, S., Recker, R. R., Gallagher, T. F., & Wiltse, H. E. (1986) · Diabetes Care · doi:10.2337/diacare.9.2.173 · Cited by 99
Ellis, D. A., Naar‐King, S., Chen, X., Moltz, K. C., Cunningham, P. B., & Carcone, A. I. (2012) · Annals of Behavioral Medicine · doi:10.1007/s12160-012-9378-1 · Cited by 99
Berrien, V., Salazar, J. C., Reynolds, E., & McKay, K. (2004) · AIDS Patient Care and STDs · doi:10.1089/1087291041444078 · Cited by 99
Management ofHelicobacter pylorieradication – the influence of structured counselling and follow‐up
Aleidan, F. A. S., McElnay, J. C., Scott, M., & McConnell, J. B. (2002) · British Journal of Clinical Pharmacology · doi:10.1046/j.0306-5251.2001.01531.x · Cited by 98
Wu, J. R., Corley, D., Lennie, T. A., & Moser, D. K. (2011) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2011.09.006 · Cited by 98
Kalichman, S. C., Cherry, C., Kalichman, M. O., Amaral, C. M., White, D., Pope, H. L., Swetzes, C., Eaton, L. A., Macy, R., & Cain, D. N. (2011) · American Journal of Public Health · doi:10.2105/ajph.2010.197608 · Cited by 97
Bodsworth, N., Crooks, R. J., Borelli, S., Vejlsgaard, G. L., Paavonen, J. A., Worm, A. M., Uexkull, N., Esmann, J., Strand, A., Ingamells, A. J., et al. (1997) · Sexually Transmitted Infections · doi:10.1136/sti.73.2.110 · Cited by 96
Nurse-led adherence support in hypertension: a randomized controlled trial
Schroeder, K. (2005) · Family Practice · doi:10.1093/fampra/cmh717 · Cited by 96
Levy, M. L., Robb, M., ALLEN, J., DOHERTY, C., Bland, J. M., & Winter, R. J. D. (2000) · Respiratory Medicine · doi:10.1053/rmed.2000.0861 · Cited by 95
Out-patient Compliance with Antidepressant Medication
Myers, E. D., & Branthwaite, A. (1992) · The British Journal of Psychiatry · doi:10.1192/bjp.160.1.83 · Cited by 94
Nachega, J. B., Chaisson, R. E., Goliath, R. T., Efron, A., Chaudhary, M. A., Ram, M., Morroni, C., Schoeman, H., Knowlton, A. R., & Maartens, G. (2010) · AIDS · doi:10.1097/qad.0b013e328339e20e · Cited by 94
Comparison of once-daily to twice-daily treatment with mometasone furoate dry powder inhaler
Noonan, M. J., Karpel, J. P., Bensch, G. W., Ramsdell, J., Webb, D. R., Nolop, K. B., & Lutsky, B. N. (2001) · Annals of Allergy Asthma & Immunology · doi:10.1016/s1081-1206(10)62353-8 · Cited by 93
Bisserbe, J. C., Lane, R. M., Flament, M. F., & France-Belgian OCD Study Group (1997) · European Psychiatry · doi:10.1016/s0924-9338(97)89646-0 · Cited by 92
Enhancing adherence to prevent depression relapse in primary care
Lin, E. H. B., Korff, M. V., Ludman, E. J., Rutter, C. M., Bush, T. M., Simon, G. E., Unützer, J., Walker, E., & Katon, W. J. (2003) · General Hospital Psychiatry · doi:10.1016/s0163-8343(03)00074-4 · Cited by 92
(1982) · Hypertension · doi:10.1161/01.hyp.4.3.415 · Cited by 92
Interventions for Seropositive Injectors—Research and Evaluation
Purcell, D. W., Metsch, L. R., Latka, M. H., Santibanez, S. S., Gomez, C. A., Eldred, L. J., & Latkin, C. A. (2004) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/01.qai.0000140609.44016.c4 · Cited by 91
Evaluation of a Pharmaceutical Care Program for Hypertensive Patients in Rural Portugal
Garçao, J. A., & Cabrita, J. (2002) · Journal of the American Pharmaceutical Association (1996) · doi:10.1331/108658002762063691 · Cited by 91
Improving Adherence and Reducing Medication Discrepancies in Patients with Diabetes
Grant, R. W., Devita, N. G., Singer, D. E., & Meigs, J. B. (2003) · Annals of Pharmacotherapy · doi:10.1345/aph.1c452 · Cited by 91
Valenstein, M. M., Kavanagh, J., Lee, T. A., Reilly, P., Dalack, G. W., Grabowski, J., Smelson, D. A., Ronis, D. L., Ganoczy, D. A., Woltmann, E. M., et al. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbp121 · Cited by 91
The HAART cell phone adherence trial (WelTel Kenya1): a randomized controlled trial protocol
Lester, R. T., Mills, E. J., Kariri, A., Ritvo, P., Chung, M., Jack, W., Habyarimana, J., Karanja, S., Barasa, S., Nguti, R., et al. (2009) · Trials · doi:10.1186/1745-6215-10-87 · Cited by 91
Combination pharmacotherapy to prevent cardiovascular disease: present status and challenges
Working Group on the Summit on Combination Therapy for CVD (2013) · European Heart Journal · doi:10.1093/eurheartj/eht407 · Cited by 91
Nurse management for hypertensionA systems approach
Rudd, P., Miller, N. H., KAUFMAN, J., KRAEMER, H. C., Bandura, A., Greenwald, G., & DeBusk, R. F. (2004) · American Journal of Hypertension · doi:10.1016/s0895-7061(04)00867-2 · Cited by 91
Impact of medication packaging on adherence and treatment outcomes in older ambulatory patients
Schneider, P. J., Murphy, J. E., & Pedersen, C. A. (2008) · Journal of the American Pharmacists Association · doi:10.1331/japha.2008.07040 · Cited by 90
Cost-effectiveness of a worksite hypertension treatment program.
Logan, A. G., Milne, B. J., Achber, C., Campbell, W., & Haynes, R. B. (1981) · Hypertension · doi:10.1161/01.hyp.3.2.211 · Cited by 90
Self-citationWohl, A. R., Garland, W., Valencia, R., Squires, K., Witt, M. D., Kovács, A., Larsen, R. A., Hader, S., Anthony, M., & Weidle, P. J. (2006) · Clinical Infectious Diseases · doi:10.1086/503906 · Cited by 90
Patient compliance with antibiotic regimens
Sharpe, T. R., & Mikeal, R. L. (1974) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/31.5.479 · Cited by 90
Kunutsor, S. K., Walley, J. D., Katabira, E. T., Muchuro, S., Balidawa, H., Namagala, E., & Ikoona, E. N. (2011) · AIDS and Behavior · doi:10.1007/s10461-011-9927-9 · Cited by 89
McCrindle, B. W., O'Neill, M. B., Cullen-Dean, G., & Helden, E. (1997) · The Journal of Pediatrics · doi:10.1016/s0022-3476(97)70353-6 · Cited by 89
Holstad, M. M., DiIorio, C. K., Kelley, M. E., Resnicow, K., & Sharma, S. (2010) · AIDS and Behavior · doi:10.1007/s10461-010-9865-y · Cited by 88
Brown, C., Wright, R. G., & Christensen, D. B. (1987) · Psychiatric Services · doi:10.1176/ps.38.1.55 · Cited by 88
Hesselink, A. E., Penninx, B. W. J. H., van der Windt, D., van Duin, B. J., de Vries, P. W., Twisk, J. W. R., Bouter, L. M., & van Eijk, J. T. M. (2004) · Patient Education and Counseling · doi:10.1016/j.pec.2003.08.007 · Cited by 88
van Es, S. M., Nagelkerke, A. F., Colland, V. T., Scholten, R. J. P. M., & Bouter, L. M. (2001) · Patient Education and Counseling · doi:10.1016/s0738-3991(00)00195-6 · Cited by 87
Alhalaiqa, F., Deane, K. H., Al-Nawafleh, A. H., Clark, A., & Gray, R. J. (2011) · Journal of Human Hypertension · doi:10.1038/jhh.2010.133 · Cited by 87
Incentives vs outreach workers for latent tuberculosis treatment in drug users
Malotte, C. K., Hollingshead, J. R., & Larro, M. (2001) · American Journal of Preventive Medicine · doi:10.1016/s0749-3797(00)00283-x · Cited by 87
Simon, S. R., Majumdar, S. R., Prosser, L. A., Salem-Schatz, S., Warner, C., Kleinman, K., Miroshnik, I., & Soumerai, S. B. (2005) · The American Journal of Medicine · doi:10.1016/j.amjmed.2004.12.023 · Cited by 87
Diabetes Personal Trainer Outcomes
Nansel, T. R., Iannotti, R. J., Simons‐Morton, B. G., Cox, C., Plotnick, L., Clark, L. M., & Zeitzoff, L. (2007) · Diabetes Care · doi:10.2337/dc06-2621 · Cited by 87
Effect of Computer-Based Learning on Diabetes Knowledge and Control
Wise, P. H., Dowlatshahi, D., Farrant, S., Fromson, S., & Meadows, K. (1986) · Diabetes Care · doi:10.2337/diacare.9.5.504 · Cited by 87
Tan, M. Y., Magarey, J. M., Chee, S. S., Lee, L. F., & Tan, M. H. (2011) · Health Education Research · doi:10.1093/her/cyr047 · Cited by 87
Continuous quality improvement can improve glycemic control for HMO patients with diabetes
O’Connor, P. J. (1996) · Archives of Family Medicine · doi:10.1001/archfami.5.9.502 · Cited by 87
Matsuyama, J. R., Mason, B. J., & Jue, S. G. (1993) · Annals of Pharmacotherapy · doi:10.1177/106002809302700705 · Cited by 87
Testing a Nurse-Tailored HIV Medication Adherence Intervention
Holzemer, W. L., Henry, S. B., Portillo, C. J., Grimes, R., Welch, J., Wantland, D. J., & Mullan, J. T. (2006) · Nursing Research · doi:10.1097/00006199-200605000-00005 · Cited by 86
Increasing compliance. Patient-operated hypertension groups
Nessman, D. G. (1980) · Archives of Internal Medicine · doi:10.1001/archinte.140.11.1427 · Cited by 86
Silverman, B. L., Blethen, S. L., Reiter, E. O., Attie, K. M., Neuwirth, R. B., & Ford, K. M. (2002) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem.2002.15.s2.715 · Cited by 85
Klein, A., Otto, G., & Krämer, I. (2009) · Transplantation · doi:10.1097/tp.0b013e318199d122 · Cited by 84
Swartz, M. S., Swanson, J. W., Wagner, H. R., Burns, B. J., & Hiday, V. A. (2001) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-200109000-00003 · Cited by 84
Christensen, A., Osterberg, L. G., & Hansen, E. (2009) · Journal of Hypertension · doi:10.1097/hjh.0b013e32832d50ef · Cited by 84
Vallès, J. (2003) · Health Policy · doi:10.1016/s0168-8510(03)00018-6 · Cited by 84
Williams, A. F., Manias, E., Walker, R. G., & Gorelik, A. (2012) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.2012.05950.x · Cited by 83
Enhancing commitment improves adherence to a medical regimen.
Putnam, D. E., Finney, J. W., Barkley, P. L., & Bonner, M. J. (1994) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.62.1.191 · Cited by 83
Hovell, M. F., Sipan, C. L., Blumberg, E., Hofstetter, C. R., Slymen, D. J., Friedman, L., Moser, K., Kelley, N. J., & Vera, A. (2003) · American Journal of Public Health · doi:10.2105/ajph.93.11.1871 · Cited by 83
Hodder, S., Mounzer, K., DeJesus, E., Ebrahimi, R., Grimm, K., Esker, S., Ecker, J., Farajallah, A., & Flaherty, J. F. (2010) · AIDS Patient Care and STDs · doi:10.1089/apc.2009.0259 · Cited by 83
Improving Pediatricians' Compliance-Enhancing Practices
Maiman, L. A. (1988) · American journal of diseases of children · doi:10.1001/archpedi.1988.02150070087033 · Cited by 83
Brook, O. H., van Hout, H. P. J., Nieuwenhuyse, H., & Heerdink, E. R. (2002) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(02)00074-3 · Cited by 83
Schaffer, S. D., & Tian, L. (2004) · Clinical Nursing Research · doi:10.1177/1054773803259300 · Cited by 83
Contreras, E. M., Garcia, O. V., Claros, N. M., Gil-Guillén, V. F., von Wichmann, M. D. L. F., Martínez, J. J. C., & Fernández, R. (2005) · Blood Pressure · doi:10.1080/08037050510008977 · Cited by 83
Impact of prepackaging antimalarial drugs on cost to patients and compliance with treatment.
Yeboah‐Antwi, K., Gyapong, J. O., Asare, I. K., Barnish, G., EVANS, D. B., & Adjei, S. (2001) · Europe PMC (PubMed Central) · Cited by 83
Freemantle, N., Nazareth, I., Eccles, M., Wood, J., & Haines, A. (2002) · PubMed Central · Cited by 82
Gialamas, A., Yelland, L. N., Ryan, P., Willson, K. J., Laurence, C., Bubner, T., Tideman, P. A., & Beilby, J. (2009) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.2009.tb02910.x · Cited by 82
Macalino, G. E., Hogan, J. W., Mitty, J. A., Bazerman, L. B., DeLong, A. K., Loewenthal, H. G., Caliendo, A. M., & Flanigan, T. (2007) · AIDS · doi:10.1097/qad.0b013e32811ebf68 · Cited by 82
[Adherence to very active antiretroviral treatment: impact of individualized assessment].
Knobel, H., Carmona, A., López, J. L., Gimeno, J. L., Saballs, P., Gonzalez, A., Guelar, A., & Díez‐Pérez, A. (1999) · PubMed · Cited by 81
Effect on disability outcomes of a depression relapse prevention program
Von Korff, M., Katon, W., Rutter, C., Ludman, E., Simon, G., Lin, E., & Bush, T. (2003) · Psychosomatic Medicine · doi:10.1097/01.psy.0000097336.95046.0c · Cited by 81
Comprehensive discharge follow-up in patients’ homes by GPs and district nurses of elderly patients
Rytter, L., Jakobsen, H. N., Rønholt, F., Hammer, A. V., Andreasen, A. H., Nissen, A., & Kjellberg, J. (2010) · Scandinavian Journal of Primary Health Care · doi:10.3109/02813431003764466 · Cited by 81
Grancelli, H., Varini, S. D., Ferrante, D., Schwartzman, R., Zambrano, C., Soifer, S., Nul, D. R., & Doval, H. C. (2003) · Journal of Cardiac Failure · doi:10.1054/jcaf.2003.33 · Cited by 81
Howe, C. J., Jawad, A. F., Tuttle, A., Moser, J. T., Preis, C., Buzby, M., & Murphy, K. M. (2005) · Journal of Pediatric Nursing · doi:10.1016/j.pedn.2004.12.010 · Cited by 81
Zermansky, A. G., Petty, D., Raynor, D. T., Lowe, C. M., Freemantle, N., & Vail, A. (2002) · Health Technology Assessment · doi:10.3310/hta6200 · Cited by 81
Nieuwkerk, P. T., Nierman, M. C., Vissers, M. N., Locadia, M., Greggers-Peusch, P., Knape, L. P. M., Kastelein, J. J. P., Sprangers, M. A. G., de Haes, J. C. J. M., & Stroes, E. S. G. (2012) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2012.04.045 · Cited by 80
Home Visits to Improve Adherence to Highly Active Antiretroviral Therapy
Williams, A. B., Fennie, K., Bova, C., Burgess, J. D., Danvers, K., & Dieckhaus, K. D. (2006) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/01.qai.0000221681.60187.88 · Cited by 80
Shames, R. S., Sharek, P. J., Mayer, M. L., Robinson, T. N., Hoyte, E. G., Gonzalez-Hensley, F., Bergman, D. A., & Umetsu, D. T. (2004) · Annals of Allergy Asthma & Immunology · doi:10.1016/s1081-1206(10)61426-3 · Cited by 80
The impact of a pharmacotherapy consultation on the cost and outcome of medical therapy.
Jameson, J., VanNoord, G. R., & Vanderwoud, K. (1995) · PubMed · Cited by 79
Sellwood, W., Barrowclough, C., Tarrier, N., Quinn, J., Mainwaring, J., & Lewis, S. W. (2001) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.2001.00502.x · Cited by 79
van Servellen, G. M., Nyamathi, A., Carpio, F., Pearce, D. D., Garcia-Teague, L., Herrera, G., & Lombardi, E. L. (2005) · AIDS Patient Care and STDs · doi:10.1089/apc.2005.19.745 · Cited by 78
Mundt, J. C., Clarke, G. N., Burroughs, D., Brenneman, D. O., & Griest, J. H. (2001) · Depression and Anxiety · doi:10.1002/1520-6394(2001)13:1 · Cited by 77
Ogedegbe, G. G., Schoenthaler, A., Richardson, T., Lewis, L. M., BeLue, R., Espinosa, E., Spencer, J. K., Allegrante, J. P., & Charlson, M. E. (2006) · Contemporary Clinical Trials · doi:10.1016/j.cct.2006.04.002 · Cited by 77
Farooq, S., Nazar, Z., Irfan, M., Akhter, J., Gul, E., Irfan, U. M., & Naeem, F. (2011) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.110.085340 · Cited by 77
Compliance differences following administration of theophylline at six- and twelve-hour intervals.
Dg, T., Vanderpool, G. E., Ms, C., Eg, P., & Dl, S. (1980) · PubMed · Cited by 77
The Effect of Packaging and Instruction on Outpatient Compliance with Medication Regimens
Linkewich, J. A., Catalano, R. B., & Flack, H. L. (1974) · Annals of Pharmacotherapy · doi:10.1177/106002807400800102 · Cited by 77
Study, T. S. H. C., Weber, R. K., Christen, L., Christen, S., Tschopp, S., Znoj, H., Schneider, C. B., Schmitt, J., Opravil, M., Günthard, H. F., et al. (2004) · Antiviral Therapy · doi:10.1177/135965350400900111 · Cited by 76
Azrin, N. H., & Teichner, G. A. (1998) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(98)00036-9 · Cited by 76
Brook, O. H., van Hout, H. P. J., Stalman, W. A. B., Nieuwenhuyse, H., Bakker, B., Heerdink, E. R., & de Haan, M. (2005) · Psychiatric Services · doi:10.1176/appi.ps.56.4.487 · Cited by 76
Murphy, D. A., Lu, M. C., MARTIN, D. J., Hoffman, D., & Marelich, W. D. (2002) · Journal of the Association of Nurses in AIDS Care · doi:10.1177/1055329002238026 · Cited by 76
An Evaluation of a Self-Management Program for Adults with Asthma
Berg, J. P., Dunbar‐Jacob, J. M., & Sereika, S. M. (1997) · Clinical Nursing Research · doi:10.1177/105477389700600304 · Cited by 76
Wang, H., Zhou, J., Huang, L., Li, X., Fennie, K., & Williams, A. B. (2010) · Journal of Clinical Nursing · doi:10.1111/j.1365-2702.2009.03048.x · Cited by 75
Gupta, A. K., Konnikov, N., & Lynde, C. W. (2001) · Journal of the American Academy of Dermatology · doi:10.1067/mjd.2001.110874 · Cited by 75
Electronic monitoring: Adherence assessment or intervention?
Wagner, G. J., & Ghosh‐Dastidar, B. (2002) · HIV Clinical Trials · doi:10.1310/xgxu-fudk-a9qt-mptf · Cited by 75
Evaluation of Home‐Based Follow‐Up of High‐Risk Elderly Patients Discharged from Hospital
Naunton, M., & Peterson, G. M. (2003) · Journal of Pharmacy Practice and Research · doi:10.1002/jppr2003333176 · Cited by 74
Informing patients about tardive dyskinesia
Chaplin, R., & Kent, A. (1998) · The British Journal of Psychiatry · doi:10.1192/bjp.172.1.78 · Cited by 74
Improving Medication Compliance by Counseling and Special Prescription Container
Rehder, T. L., McCoy, L. K., Blackwell, B., Whitehead, W., & Robinson, A. (1980) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/37.3.379 · Cited by 74
Sarna, A., Luchters, S. M. F., Geibel, S., Chersich, M., Munyao, P., Kaai, S., Mandaliya, K. N., Shikely, K., Temmerman, M., & Rutenberg, N. (2008) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e3181806bf1 · Cited by 73
Adherence to Oral Montelukast and Inhaled Fluticasone in Children with Persistent Asthma
Sherman, J., Patel, P., Hutson, A. D., Chesrown, S. E., & Hendeles, L. (2001) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.21.20.1464.34485 · Cited by 73
Wu, A. W., Snyder, C. F., Huang, I., Skolasky, R. L., McGruder, H. F., Celano, S. A., Selnes, O. A., & Andrade, A. S. (2006) · AIDS Patient Care and STDs · doi:10.1089/apc.2006.20.773 · Cited by 73
Multidisciplinary HIV Adherence Intervention: A Randomized Study
Levy, R., Rayner, C. R., Fairley, C. K., Kong, D. C. M., Mijch, A. M., Costello, K., McArthur, C. J., & Melbourne Adherence Group (2004) · AIDS Patient Care and STDs · doi:10.1089/apc.2004.18.728 · Cited by 73
Efficacy and Safety of Oral Weekly Ibandronate in the Treatment of Postmenopausal Osteoporosis
Cooper, C. C., Emkey, R. D., McDonald, R. H., HAWKER, G. A., Bianchi, G., Wilson, K., & Schimmer, R. C. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-022029 · Cited by 72
Impact of pharmacist-conducted home visits on the outcomes of lipid-lowering drug therapy
Peterson, G. M., Fitzmaurice, K. D., Naunton, M., Vial, J. H., Stewart, K., & Krum, H. (2004) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1046/j.1365-2710.2003.00532.x · Cited by 72
Influencing medication adherence among women with AIDS
Jones, D. L., Ishii, M., LaPerriere, A. R., Stanley, H., Antoni, M. H., Ironson, G. H., Schneiderman, N., Splunteren, F. V., Cassells, A. N., Alexander, K., et al. (2003) · AIDS Care · doi:10.1080/0954012031000134700 · Cited by 72
Rawlings, M. K., Thompson, M., Farthing, C., Brown, L. S., Racine, J., Scott, R. C., Crawford, K. H., Goodwin, S., Tolson, J. M., Williams, V. C., et al. (2003) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/00126334-200310010-00007 · Cited by 72
Harvey, E., Glenny, A., Kirk, S., & Summerbell, C. (2001) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000984 · Cited by 71
“Real-world” effectiveness of daily controller medicine in children with mild persistent asthma
Bukstein, D. A., Luskin, A. T., & Bernstein, A. J. (2003) · Annals of Allergy Asthma & Immunology · doi:10.1016/s1081-1206(10)61848-0 · Cited by 71
Compliance in depressed patients treated with fluoxetine or amitriptyline
Demyttenaere, K., Ganse, E. H. V., Grégoire, J. C., Gaens, E., & Mesters, P. (1998) · International Clinical Psychopharmacology · doi:10.1097/00004850-199801000-00002 · Cited by 71
Guthrie, R. M. (2001) · Clinical Therapeutics · doi:10.1016/s0149-2918(01)80084-9 · Cited by 71
Apter, A. J., Wang, X., Bogen, D. K., Rand, C. S., McElligott, S. C., Polsky, D. E., Gonzalez, R., Priolo, C., Adam, B. I., Geer, S., et al. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.05.010 · Cited by 70
Rapoff, M. A., Belmont, J. M., Lindsley, C. B., Olson, N. Y., Morris, J., & Padur, J. (2002) · Health Psychology · doi:10.1037//0278-6133.21.6.620 · Cited by 69
The effectiveness of personalized coronary heart disease and stroke risk communication
Powers, B. J., Danus, S. M., Grubber, J. M., Olsen, M. K., Oddone, E. Ž., & Bosworth, H. B. (2011) · American Heart Journal · doi:10.1016/j.ahj.2010.12.021 · Cited by 69
Wong, B. S. M., & Norman, D. C. (1987) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1987.tb01314.x · Cited by 69
Scott, M. K., Widmer, L. B., Stacey, S., & Popovich, N. G. (1995) · The Science of Diabetes Self-Management and Care · doi:10.1177/014572179502100207 · Cited by 69
Johnson, M. O., Dilworth, S. E., Taylor, J. M., & Neilands, T. B. (2010) · Annals of Behavioral Medicine · doi:10.1007/s12160-010-9230-4 · Cited by 69
Bailey, W. C., Kohler, C. L., Richards, J. M., Windsor, R. A., Brooks, C. M., Gerald, L. B., Martin, B., Higgins, D. M., & Liu, T. (1999) · Archives of Internal Medicine · doi:10.1001/archinte.159.20.2422 · Cited by 69
Knowledge and adherence to antihypertensive therapy in primary care: results of a randomized trial
Amado, E., Ribera, E. P., Pacheco‐Huergo, V., & Borràs, J. M. (2011) · Gaceta Sanitaria · doi:10.1016/j.gaceta.2010.09.015 · Cited by 69
Edworthy, S. M., & Devins, G. M. (1999) · PubMed · Cited by 68
Schmaling, K. B., Blume, A. W., & Afari, N. (2001) · Journal of Clinical Psychology in Medical Settings · doi:10.1023/a:1011365519345 · Cited by 68
Stringer, J. S. A., Sinkala, M., Stout, J. P., Goldenberg, R. L., Acosta, E. P., Chapman, V., Kumwenda, R., & Vermund, S. H. (2003) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/00126334-200304150-00007 · Cited by 68
Santschi, V., Rodondi, N., Bugnon, O., & Burnier, M. (2008) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2007.12.007 · Cited by 68
Hornung, W. P., Klingberg, S., Feldmann, R., Schonauer, K., & Mönking, H. S. (1998) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1998.tb09990.x · Cited by 68
Maspero, J. F., & Leff, J. A. (2001) · Current Medical Research and Opinion · doi:10.1185/0300799039117037 · Cited by 68
Telemonitoring of Medication Adherence in Patients with Schizophrenia
Frangou, S., Sachpazidis, I., Stassinakis, A., & Sakas, G. (2005) · Telemedicine Journal and e-Health · doi:10.1089/tmj.2005.11.675 · Cited by 68
Tobari, H., Arimoto, T., Shimojo, N., Yuhara, K., Noda, H., Yamagishi, K., & Iso, H. (2010) · American Journal of Hypertension · doi:10.1038/ajh.2010.127 · Cited by 68
Gray, T. A., Fenerty, C., Harper, R. A., Spencer, A. F., Campbell, M., Henson, D. B., & Waterman, H. A. (2011) · Eye · doi:10.1038/eye.2011.269 · Cited by 68
Randomised controlled trial of general practice based asthma clinics
Heard, A. R., Richards, I., Alpers, J. H., Pilotto, L., Smith, B. J., & Black, J. A. (1999) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1999.tb123522.x · Cited by 67
Flagged first, then by citations
5 of the 645 references couldn’t be matched to a known paper.
Research works printed but not linked: 33
- Chamorro, 2011, Effect of pharmacist involvement in adherence to medications in patients with high to moderate cardiovascular risk (Study EMDADER-CV-INCUMPLIMIENTO), Atencion Primaria, 43, 245
- Marquez Contreras, 2004, Efficacy of an intervention to improve treatment compliance in hyperlipidemias, Atencion Primaria, 33, 443
- Marquez Contreras, 2007, Therapy compliance in cases of hyperlipaemia, as measured through electronic monitors. Is a reminder calendar to avoid forgetfulness effective?, Atencion Primaria, 39, 661
- Strang, 1981, The effects of family therapy on treatment compliance in schizophrenia, Psychopharmacology Bulletin, 17, 87
- Yopp, 2004, The Impact of Family Functioning on Treatment Adherence and Metabolic Control for Adolescents with Poorly Controlled T1DM [dissertation]
- Barcelo, 2001, An intervention to improve diabetes control in Chile, Revista Panamericana de Salud Publica/Pan American Journal of Public Health, 10, 328
- Binstock, 1986, Therapeutic adherence programme improves compliance and lowers blood pressure, Journal of Hypertension, 4 Suppl, 375
- Birrer, 1984, Hypertension: a double-blind study of compliance in an urban community, Family Practice Research Journal, 3, 251
- Bonner, 2002, An individualized intervention to improve asthma management among urban Latino and African-American families, Journal of Asthma, 39, 167, 10.1081/JAS-120002198 · DOI
- Bouvy, 2003, Guidance improves compliance. Pharmacist stimulates proper use of loop diuretics in patient with heart failure, Pharmaceutisch Weekblad, 138, 1432
- Celik, 1997, Comparison of the clinical efficacy of azithromycin and cerufoxime axetile in the treatment of patients with acute otitis media, Mikrobiyoloji Bulteni, 31, 253
- Edworthy, 1999, Improving medication adherence through patients education distinguishing between appropriate and inappropriate utilization, Journal of Rheumatology, 26, 1793
- Kelly, 1991, Medication compliance and health education among outpatients with chronic mental disorders [erratum], Medical Care, 29, 889
- Leal, 2004, Written information on the use of aerosols in COPD patients. Can we improve their use? [see comment], Atencion Primaria, 33, 6
- Levesque, 1983, Comparative efficacy of two dosage regimens of cimetidine in the treatment of symptomatic duodenal ulcer: results of a multicenter clinical trial, Current Therapeutic Research, Clinical and Experimental, 33, 70
- Marquez Contreras, 2004, Effectiveness of an intervention to provide information to patients with hypertension as short text messages and reminders sent to their mobile phone (HTA-Alert), Atencion Primaria, 34, 399
- Ogedegbe, 2007, An RCT of the effect of motivational interviewing on medication adherence in hypertensive African Americans: rationale and design, Contemporary Clinical Trials, 28, 169, 10.1016/j.cct.2006.04.002 · DOI
- Phan, 1995, Enhancing client adherence to psychotropic medication regimens: a psychosocial nursing approach, International Journal of Psychiatric Nursing Research, 2, 146
- Purcell, 2004, Interventions for seropositive injectors-research and evaluation: an integrated behavioral intervention with HIV-positive injection drug users to address medical care, adherence, and risk reduction, Journal of Acquired Immune Deficiency Syndromes, 37, S110, 10.1097/01.qai.0000140609.44016.c4 · DOI
- Razali, 1997, Health education and drug counseling for schizophrenia, International Medical Journal, 4, 187
- Rickheim, 2002, Assessment of group versus individual diabetes education: a randomized study, Diabetes Care, 25, 269, 10.2337/diacare.25.2.269 · DOI
- Rodriguez, 2003, Effectiveness of a group educational intervention in patients with chronic obstructive pulmonary disease, Enfermeria Clinica, 13, 131
- Sanchez, 2002, Treatment of latent tuberculosis infection in injecting drug users co-infected by HIV, Enfermedades Emergentes, 4, 62
- Tapanya S A biopsychosocial intervention program to improve medical regimen adherence and glycemic control in type II diabetic patients Dissertation Abstracts International: Section B: the Sciences and Engineering 1997
- Vander Stichele, 1992, Measuring patient compliance with electronic monitoring: lisinopril versus atenolol in essential hypertension, Post Market Surveillance, 6, 77
- Vetter, 1999, Efficacy and safety of once-daily and twice-daily clarithromycin formulations in the treatment of acute exacerbations of chronic bronchitis, Advances in Therapy, 16, 13
- Andres Rodriguez, 2007, Assessment of knowledge/compliance in a drug therapy follow-up program involving type 2 diabetic patients in community pharmacy: a randomized study, Pharmaceutical Care Espana, 9, 2
- Marquez Contreras, 2000, Therapeutic compliance in hypertension. Trial of two-year health education intervention, Atencion Primaria, 26, 5
- Marquez Contreras, 2009, Non-pharmacological intervention as a strategy to improve antihypertensive treatment compliance, Atencion Primaria, 41, 501
- Gordis, 1979, Conceptual and methodologic problems in measuring compliance, 23
- Haynes, 1979, Determinants of compliance: the disease and the mechanics of treatment, 49
- Sackett, 1979, The magnitude of adherence and nonadherence, 11
- Stephenson, 1993, Is this patient taking their medication?, JAMA, 269, 2779, 10.1001/jama.1993.03500210079036 · DOI
Cited by
Sorted by citations
Ibanez, B., James, S., Agewall, S., Antunes, M. J., Bucciarelli-Ducci, C., Bueno, H., Caforio, A. L. P., Crea, F., Goudevenos, J. A., Halvorsen, S., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehx393 · Cited by 9,728
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000065 · Cited by 7,391
2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes
Knuuti, J., Wijns, W., Saraste, A., Capodanno, D., Barbato, E., Funck-Brentano, C., Prescott, E., Storey, R. F., Deaton, C., Cuisset, T., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz425 · Cited by 7,166
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.11.006 · Cited by 6,616
Kirk, J. M. W., MacDonald, A., Lavender, P., Dean, J. M., & Rubin, G. (2017) · Biomedicine Hub · doi:10.1159/000480347 · Cited by 3,902
Metadata
- Authors
- Nieuwlaat, R., Wilczynski, N., Navarro, T., Hobson, N., Jeffery, R., Keepanasseril, A., Agoritsas, T., Mistry, N., Iorio, A., Jack, S., Sivaramalingam, B., Iserman, E., Mustafa, R. A., Jedraszewski, D., Cotoi, C., & Haynes, R. B.
- Affiliations
- Hamilton General Hospital (CA)
- McMaster University (CA)
- St. Michael's Hospital (CA)
- University of Guelph (CA)
- ORCID
- Venue
- Cochrane Database of Systematic Reviews
- Publisher
- Wiley
- Published
- 2014-11-20
- Volume
- 2014
- Issue
- 11
- Pages
- CD000011-CD000011
- ISSN
- 1361-6137 (ISSN-L)
- 1465-1858
- PMC
- PMC7263418
- OpenAlex
- W1594567624
- Cited by
- 2,945
- References
- 645
- Citations by year
- 2026: 64 · 2025: 119 · 2024: 108 · 2023: 147 · 2022: 157 · 2021: 177 · 2020: 200 · 2019: 190 · 2018: 209 · 2017: 244 · 2016: 224 · 2015: 191 · 2014: 214
- FWCI
- 37.90
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Cochrane Database of Systematic Reviews (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Archive ouverte UNIGE (University of Geneva) (publishedVersion)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
- Funders
- Canadian Institutes of Health Research
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Health Professions › Pharmacy › Pharmacy and Medical Practices
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Patient Safety and Medication Errors
- Keywords
- medication adherence, adherence interventions, self-administered medication, clinical outcomes, risk of bias, quality of evidence, pill organizers, pharmacists
- MeSH terms
- Drug Therapy, Humans, Patient Education as Topic, Self Administration, Randomized Controlled Trials as Topic, Publication Bias, Medication Adherence
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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