Cited by 1,070Health Policy Implementation ScienceHealth Sciences Research and EducationClinical practice guidelines implementation

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Local opinion leaders: effects on professional practice and health care outcomes

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Flodgren, Gerd, Parmelli, Elena, Doumit, Gaby, Gattellari, Melina, O'Brien, Mary Ann, Grimshaw, Jeremy, Eccles, Martin P·2011·Cochrane Database of Systematic Reviews

DOI 10.1002/14651858.cd000125.pub4PMC PMC4172331

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Abstract

BACKGROUND: Clinical practice is not always evidence-based and, therefore, may not optimise patient outcomes. Opinion leaders disseminating and implementing 'best evidence' is one method that holds promise as a strategy to bridge evidence-practice gaps. OBJECTIVES: To assess the effectiveness of the use of local opinion leaders in improving professional practice and patient outcomes. SEARCH STRATEGY: We searched Cochrane EPOC Group Trials Register, the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, HMIC, Science Citation Index, Social Science Citation Index, ISI Conference Proceedings and World Cat Dissertations up to 5 May 2009. In addition, we searched reference lists of included articles. SELECTION CRITERIA: Studies eligible for inclusion were randomised controlled trials investigating the effectiveness of using opinion leaders to disseminate evidence-based practice and reporting objective measures of professional performance and/or health outcomes. DATA COLLECTION AND ANALYSIS: Two review authors independently extracted data from each study and assessed its risk of bias. For each trial, we calculated the median risk difference (RD) for compliance with desired practice, adjusting for baseline where data were available. We reported the median adjusted RD for each of the main comparisons. MAIN RESULTS: We included 18 studies involving more than 296 hospitals and 318 PCPs. Fifteen studies (18 comparisons) contributed to the calculations of the median adjusted RD for the main comparisons. The effects of interventions varied across the 63 outcomes from 15% decrease in compliance to 72% increase in compliance with desired practice. The median adjusted RD for the main comparisons were: i) Opinion leaders compared to no intervention, +0.09; ii) Opinion leaders alone compared to a single intervention, +0.14; iii) Opinion leaders with one or more additional intervention(s) compared to the one or more additional intervention(s), +0.10; iv) Opinion leaders as part of multiple interventions compared to no intervention, +0.10. Overall, across all 18 studies the median adjusted RD was +0.12 representing a 12% absolute increase in compliance in the intervention group. AUTHORS' CONCLUSIONS: Opinion leaders alone or in combination with other interventions may successfully promote evidence-based practice, but effectiveness varies both within and between studies. These results are based on heterogeneous studies differing in terms of type of intervention, setting, and outcomes measured. In most of the studies the role of the opinion leader was not clearly described, and it is therefore not possible to say what the best way is to optimise the effectiveness of opinion leaders.

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Diffusion of Innovations 1
Rogers, E. M., Singhal, A., & Quinlan, M. M. (2019) · Routledge eBooks · doi:10.4324/9780203710753-35 · Cited by 37,670
Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
(2008) · doi:10.1002/9780470712184 · Cited by 25,048
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Guyatt, G. H., Oxman, A. D., Vist, G. E., Kunz, R., Falck-Ytter, Y., Alonso-Coello, P., & Schünemann, H. J. (2008) · BMJ · doi:10.1136/bmj.39489.470347.ad · Cited by 23,305
Pharmacological interventions for somatoform disorders in adults
Kleinstäuber, M., Witthöft, M., Steffanowski, A., van Marwijk, H., Hiller, W., & Lambert, M. J. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010628.pub2 · Cited by 11,369
Audit and feedback: effects on professional practice and healthcare outcomes
Ivers, N., Jamtvedt, G., Flottorp, S., Young, J. M., Odgaard-Jensen, J., French, S. D., O'Brien, M. A., Johansen, M., Grimshaw, J., & Oxman, A. D. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000259.pub3 · Cited by 5,485
Self-citation
Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement
Moher, D., Cook, D. J., Eastwood, S., Olkin, I., Rennie, D., & Stroup, D. F. (1999) · The Lancet · doi:10.1016/s0140-6736(99)04149-5 · Cited by 4,826
Untitled work
(2008) · Cited by 3,790
Assessing Risk of Bias in Included Studies
Higgins, J. P., & Altman, D. G. (2008) · Cochrane Handbook for Systematic Reviews of Interventions · doi:10.1002/9780470712184.ch8 · Cited by 3,396
The answer is 17 years, what is the question: understanding time lags in translational research
Morris, Z. S., Wooding, S., & Grant, J. (2011) · Journal of the Royal Society of Medicine · doi:10.1258/jrsm.2011.110180 · Cited by 3,340
Effectiveness and efficiency of guideline dissemination and implementation strategies
Grimshaw, J., Thomas, R., MacLennan, G., Fraser, C., Ramsay, C., Vale, L., Whitty, P., Eccles, M., Matowe, L., Shirran, L., et al. (2004) · Health Technology Assessment · doi:10.3310/hta8060 · Cited by 3,044
Self-citation

Show all 117 references

Research works printed but not linked: 5

Hodnett, 1994, A strategy to promote research-based nursing care: effects on childbirth outcomes. Final report of project no. 6606-4076-57E
Nicolas, 1996, Cost analysis, consensus conference, medical audit, Journal D'Economie Medicale, 14
Doumit, 2006, Opinion leaders - Effectiveness, Identification, Stability, Specificity, and Mechanism of Action
Hiss RG MacDonald R David WR Identification of physician educational influentials in small community hospitals Washington DC Proceedings of the Seventeenth Annual Conference on Research in Medical Education 1978 283 8
Doumit, 2007, Local opinion leaders: effects on professional practice and heath care outcomes, Cochrane Database of Systematic Reviews, 10.1002/14651858.MR000006.pub3 · DOI · Paper page

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BackgroundMethod
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Novak, I., & McIntyre, S. J. (2010) · Australian Occupational Therapy Journal · doi:10.1111/j.1440-1630.2010.00861.x · Cited by 68
Statins for primary prevention of cardiovascular disease
French, L., & Smith, J. W. (2012) · Australian Prescriber · doi:10.18773/austprescr.2012.034 · Cited by 66
Multi-level factors influence the implementation and use of complex innovations in cancer care: a multiple case study of synoptic reporting
Urquhart, R., Porter, G. A., Sargeant, J. M., Jackson, L. A., & Grunfeld, E. (2014) · Implementation Science · doi:10.1186/s13012-014-0121-0 · Cited by 65
“Systematic reviews [9, 10, 33-36] on the movement of”
Background
Knowledge Translation: Putting the “Practice” in Evidence-Based Practice
MacDermid, J. C., & Graham, I. D. (2009) · Hand Clinics · doi:10.1016/j.hcl.2008.10.003 · Cited by 64
Assessing organisational readiness for change: use of diagnostic analysis prior to the implementation of a multidisciplinary assessment for acute stroke care
Hamilton, S., McLaren, S., & Mulhall, A. (2007) · Implementation Science · doi:10.1186/1748-5908-2-21 · Cited by 64
“More bang for the buck”: exploring optimal approaches for guideline implementation through interviews with international developers
Gagliardi, A. R. (2012) · BMC Health Services Research · doi:10.1186/1472-6963-12-404 · Cited by 63
Development of a theory-informed implementation intervention to improve the triage, treatment and transfer of stroke patients in emergency departments using the Theoretical Domains Framework (TDF): the T3 Trial
Craig, L., Taylor, N. J., Grimley, R., Cadilhac, D. A.-M., McInnes, E., Phillips, R., Dale, S., O’Connor, D. A., Levi, C. R., Fitzgerald, M., et al. (2017) · Implementation Science · doi:10.1186/s13012-017-0616-6 · Cited by 62
“These were as follows: multidisciplinary barrier and enabler workshop [31], interactive and didactic education programme [32, 33], use of opinion leaders [25], reminders [34] and site support [34].”
MethodSelf-citation
Putting the network in network interventions
Valente, T. W. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1712473114 · Cited by 61
Opposing expectations and suboptimal use of a local antibiotic hospital guideline: a qualitative study
Cortoos, P., Witte, K. D., Peetermans, W. E., Simoens, S., & Laekeman, G. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn143 · Cited by 61
Evidence-based practice implementation in healthcare in China: a living scoping review
Zhao, J., Bai, W., Zhang, Q., Su, Y., Wang, J., Xiao-ning, D., Zhou, Y., Kong, C., Qing, Y., Gong, S., et al. (2022) · The Lancet Regional Health - Western Pacific · doi:10.1016/j.lanwpc.2021.100355 · Cited by 63
Examining the complementarity between the ERIC compilation of implementation strategies and the behaviour change technique taxonomy: a qualitative analysis
McHugh, S., Presseau, J., Luecking, C. T., & Powell, B. J. (2022) · Implementation Science · doi:10.1186/s13012-022-01227-2 · Cited by 64
Implementation Strategies for Improving Survival After Out-of-Hospital Cardiac Arrest in the United States
Neumar, R. W., Barnhart, J., Berg, R. A., Chan, P. S., Geocadin, R. G., Luepker, R. V., Newby, L. K., Sayre, M. R., & Nichol, G. (2011) · Circulation · doi:10.1161/cir.0b013e31821d79f3 · Cited by 60
Challenges in Systematic Reviews: Synthesis of Topics Related to the Delivery, Organization, and Financing of Health Care
Bravata, D. M., McDonald, K. M., Shojania, K. G., H, V. S. M. P., & Owens, D. K. (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-142-12_part_2-200506211-00005 · Cited by 59
Measurement of a model of implementation for health care: toward a testable theory
Cook, J. M., O’Donnell, C., Dinnen, S., Coyne, J. C., Ruzek, J. I., & Schnurr, P. P. (2012) · Implementation Science · doi:10.1186/1748-5908-7-59 · Cited by 62
“Relatedly although there are several ways that peer opinion leaders have been assessed [3,71], the most common is to ask respondents from whom”
Background
Improving the Prescription of Oral Anticoagulants in Atrial Fibrillation: A Systematic Review
Pritchett, R., Bem, D., Turner, G., Thomas, G. N., Clarke, J. L., Fellows, R., Lane, D. A., & Jolly, K. B. (2019) · Thrombosis and Haemostasis · doi:10.1055/s-0038-1676835 · Cited by 59
Nursing best practice statements: an exploration of their implementation in clinical practice
Ring, N., Malcolm, C. A., Coull, A. F., Murphy‐Black, T., & Watterson, A. E. (2005) · Journal of Clinical Nursing · doi:10.1111/j.1365-2702.2005.01225.x · Cited by 58
Ventilator-associated pneumonia: Improving outcomes through guideline implementation
Sinuff, T., Muscedere, J., Cook, D., Dodek, P., & Heyland, D. K. (2008) · Journal of Critical Care · doi:10.1016/j.jcrc.2007.11.013 · Cited by 56
Leadership and Cultural Competence of Healthcare Professionals
Dauvrin, M., & Lorant, V. (2015) · Nursing Research · doi:10.1097/nnr.0000000000000092 · Cited by 56
“…(Kaplan et al., 2010) and as having a positive effect on the prevention of nosocomial infections (Ferguson, 2009), the implementation of a hand-washing culture (Roberts, Sieczkowski, Campbell, Balla, &Keenan, 2012), andonprofessional practices and healthcare outcomes (Flodgren et al., 2011).”
Background
Role for Opinion Leaders in Promoting Evidence-Based Surgery
Young, J. M. (2003) · Archives of Surgery · doi:10.1001/archsurg.138.7.785 · Cited by 56
The role of the dementia specialist nurse in acute care: a scoping review
Griffiths, P., Bridges, J., Sheldon, H., & Thompson, R. (2014) · Journal of Clinical Nursing · doi:10.1111/jocn.12717 · Cited by 55
“To succeed they would need significant expertise, seniority and authority and to be recognised as opinion leaders by senior colleagues from other disciplines (Flodgren et al. 2011).”
Background
Implementation of multidimensional knowledge translation strategies to improve procedural pain in hospitalized children
Stevens, B., Yamada, J., Promislow, S., Stinson, J., Harrison, D. M., & Victor, J. C. (2014) · Implementation Science · doi:10.1186/s13012-014-0120-1 · Cited by 55
Effectiveness of implementation strategies for the improvement of guideline and protocol adherence in emergency care: a systematic review
Ebben, R. H. A., Siqeca, F., Madsen, U. R., Vloet, L. C. M., & van Achterberg, T. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-017572 · Cited by 58
Clinical Practice Guideline Implementation Strategy Patterns in Veterans Affairs Primary Care Clinics
Hysong, S. J., Best, R. G., & Pugh, J. A. (2007) · Health Services Research · doi:10.1111/j.1475-6773.2006.00610.x · Cited by 55
Improving Test Ordering in Primary Care: The Added Value of a Small-Group Quality Improvement Strategy Compared With Classic Feedback Only
Verstappen, W. H. J. M. (2004) · The Annals of Family Medicine · doi:10.1370/afm.244 · Cited by 55
Use of Evidence-Based Practice in School Nursing: Survey of School Nurses at a National Conference
Adams, S. L. (2009) · The Journal of School Nursing · doi:10.1177/1059840509335008 · Cited by 54
Putting evidence into practice: how middle and low income countries “get it together”
Garner, P., Meremikwu, M. M., Volmink, J. A., Qian, X., & Smith, H. J. J. (2004) · BMJ · doi:10.1136/bmj.329.7473.1036 · Cited by 54
Strategies for guideline implementation in primary care focusing on patients with cardiovascular disease: a systematic review
Unverzagt, S., Oemler, M., Braun, K., & Klement, A. (2013) · Family Practice · doi:10.1093/fampra/cmt080 · Cited by 53
Public Pharmacovigilance Communication
Bahri, P. (2010) · Drug Safety · doi:10.2165/11539040-000000000-00000 · Cited by 54
Evaluation of a knowledge translation initiative for physical therapists treating patients with work disability
Gross, D. P., & Lowe, A. (2009) · Disability and Rehabilitation · doi:10.1080/01443610802355965 · Cited by 42
“Although some evidence indicate that this method is effective in hospital settings, within community-based rehabilitation settings opinion leaders may change more frequently leading to unreliable identification of these clinicians [23,28].”
Background
Effectiveness of a multifaceted intervention to improve emergency department care of low back pain: a stepped-wedge, cluster-randomised trial
Coombs, D., Machado, G. C., Richards, B. L., Needs, C., Buchbinder, R., Harris, I. A., Howard, K., McCaffery, K. J., Billot, L., Edwards, J., et al. (2021) · BMJ Quality & Safety · doi:10.1136/bmjqs-2020-012337 · Cited by 52
Strategies for improving the quality of care in psoriasis with the use of treatment goals – a report on an implementation meeting
Mrowietz, U., Kragballe, K., Nast, A., & Reich, K. (2011) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2011.04033.x · Cited by 53
The Use of a Knowledge Translation Program to Increase Use of Standardized Outcome Measures in an Outpatient Pediatric Physical Therapy Clinic: Administrative Case Report
Schreiber, J., Marchetti, G. F., Racicot, B., & Kaminski, E. (2014) · Physical Therapy · doi:10.2522/ptj.20130434 · Cited by 53
Prescription peer academic detailing to reduce inappropriate prescribing for older patients: a cluster randomised controlled trial
Rognstad, S., Brekke, M., Fetveit, A., Dalen, I., & Straand, J. (2013) · British Journal of General Practice · doi:10.3399/bjgp13x670688 · Cited by 53
Manually-generated reminders delivered on paper: effects on professional practice and patient outcomes
Tomás Pantoja, C., Grimshaw, J., Colomer, N., Castañón, C., & Léniz, J. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001174.pub4 · Cited by 57
Self-citation
Integration of patient-reported outcomes (PROs) for personalized symptom management in “real-world” oncology practices: a population-based cohort comparison study of impact on healthcare utilization
Howell, D., Li, M., Sutradhar, R., Gu, S., Iqbal, J., O’Brien, M. A., Seow, H. Y., Dudgeon, D. J., Atzema, C. L., Earle, C. C., et al. (2020) · Supportive Care in Cancer · doi:10.1007/s00520-020-05313-3 · Cited by 53
“, interactive case-based educational meetings, audit and feedback, disease site champions) [22, 23].”
BackgroundSelf-citation
The changing nature of consultation-liaison in primary care: bridging the gap between research and practice
Bower, P., & Gask, L. (2002) · General Hospital Psychiatry · doi:10.1016/s0163-8343(01)00183-9 · Cited by 53
Implementation Science
Wilson, P. M., & Kislov, R. (2022) · Cambridge University Press eBooks · doi:10.1017/9781009237055 · Cited by 58
Clinical effectiveness of a staff training intervention in mental health inpatient rehabilitation units designed to increase patients' engagement in activities (the Rehabilitation Effectiveness for Activities for Life [REAL] study): single-blind, cluster-randomised controlled trial
Killaspy, H. T., Marston, L., Green, N., Harrison, I., Lean, M., Cook, S., Mundy, T., Craig, T., Holloway, F. A., Leavey, G., et al. (2015) · The Lancet Psychiatry · doi:10.1016/s2215-0366(14)00050-9 · Cited by 55
Evaluating the impact of an intensive education workshop on evidence-informed decision making knowledge, skills, and behaviours: a mixed methods study
Yost, J., Ciliska, D. K., & Dobbins, M. (2014) · BMC Medical Education · doi:10.1186/1472-6920-14-13 · Cited by 58
The impact of social networks on knowledge transfer in long-term care facilities: Protocol for a study
Sales, A. E., Estabrooks, C. A., & Valente, T. W. (2010) · Implementation Science · doi:10.1186/1748-5908-5-49 · Cited by 50
“A class of interventions designed to promote knowledge translation, using opinion leaders, uses aspects of social network theory to foster planned behavior change or knowledge translation [17,20,25-27,45-56].”
Background
Implementation interventions to promote the uptake of evidence-based practices in stroke rehabilitation
Cahill, L. S., Carey, L. M., Lannin, N. A., Turville, M. L., Neilson, C., Lynch, E. A., McKinstry, C., Han, J. X., & O’Connor, D. A. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012575.pub2 · Cited by 51
Disseminating healthcare information: getting the message across
Marriott, S., Palmer, C., & Lelliott, P. (2000) · BMJ Quality & Safety · doi:10.1136/qhc.9.1.58 · Cited by 51

Authors: Flodgren, G., Parmelli, E., Doumit, G., Gattellari, M., O'Brien, M. A., Grimshaw, J., & Eccles, M. P.
Affiliations: University of Oxford (GB)
University of Modena and Reggio Emilia (IT)
Cleveland Clinic (US)
UNSW Sydney (AU)
McMaster University; School of Rehabilitation Science, Institute for Applied Health Sciences, Faculty of Health Sciences; 1400 Main Street West Room 403 Hamilton Ontario Canada L8S 1C7
Ottawa Health Research Institute; Clinical Epidemiology Program; 1053 Carling Avenue Ottawa ON Canada K1Y 4E9
Newcastle University (GB)
ORCID: Flodgren, Gerd
Parmelli, Elena
Doumit, Gaby
Gattellari, Melina
Grimshaw, Jeremy
Venue: Cochrane Database of Systematic Reviews
Publisher: Wiley
Published: 2011-08-10
Volume: 6
Issue: 8
Pages: CD000125-CD000125
ISSN: 1361-6137 (ISSN-L)
1465-1858
DOI: 10.1002/14651858.cd000125.pub4
PMC: PMC4172331
OpenAlex: W1656816330
Cited by: 1,070
References: 117
Citations by year: 2026: 4 · 2025: 25 · 2024: 33 · 2023: 57 · 2022: 52 · 2021: 62 · 2020: 59 · 2019: 52 · 2018: 51 · 2017: 57 · 2016: 53 · 2015: 64 · 2014: 71 · 2013: 69 · 2012: 55
FWCI: 13.05
Type: journal article
Language: en
Update notices: new_version (2019-06-24)
Open access: green
www.ncbi.nlm.nih.gov
Locations: Cochrane Database of Systematic Reviews (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
NORA - Norwegian Open Research Archives (submittedVersion, other-oa)
Newcastle University ePrints (Newcastle Univesity)
Funders: National Institute for Health and Care Research (10/4001/03)
Topics: Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
Health Sciences › Health Professions › General Health Professions › Health Sciences Research and Education
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
Keywords: opinion leaders, evidence-based practice, knowledge-practice gap, professional practice change, health care outcomes, clinical teaching, primary care, hospital care, patient outcomes, evidence dissemination, health professions education, patient safety, quality of care, health professional confidence
MeSH terms: Humans, Leadership, Practice Patterns, Physicians', Policy Making, Professional Practice, Randomized Controlled Trials as Topic, Process Assessment, Health Care, Evidence-Based Medicine, Information Dissemination

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Local opinion leaders: effects on professional practice and health care outcomes

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