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Cited by 544Photodynamic Therapy Research StudiesNanoplatforms for cancer theranosticsLuminescence and Fluorescent Materials

Activatable Photosensitizers: Agents for Selective Photodynamic Therapy

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Li, Xingshu, Kolemen, Safacan, Yoon, Juyoung, Akkaya, Engin U.·2017·Advanced Functional Materials
DOI 10.1002/adfm.201604053
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Abstract

Recent developments in the design of bifunctional and activatable photosensitizers rejuvenate the aging field of photodynamic sensitization and photodynamic therapy. While systematic studies have uncovered new dyes that can serve as potential photosensitizers, the most promising results have come from studies aimed at gaining precise control over the location and rate of cytotoxic singlet oxygen generation. As a consequence, higher selectivities and efficiencies in photodynamic treatment protocols are now within reach. This feature article highlights the variety of approaches that have been pursued to improve photodynamic therapy and to transform simple photosensitizers into smarter theranostic agents.

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Authors
Li, X., Kolemen, S., Yoon, J., & Akkaya, E. U.
Affiliations
  • Ewha Womans University (KR)
  • UNAM‐Institute of Material Science and Nanotechnology Bilkent University Ankara 06800 Turkey
  • Bilkent University (TR)
Corresponding author
  • Yoon, Juyoung
  • Akkaya, Engin U.
ORCID
Venue
Advanced Functional Materials
Publisher
Wiley
Published
2016-12-09
Volume
27
Issue
5
ISSN
  • 1616-301X (ISSN-L)
  • 1616-3028
DOI
10.1002/adfm.201604053
OpenAlex
W2560297620
Cited by
544
References
82
Citations by year
2026: 12 · 2025: 59 · 2024: 46 · 2023: 58 · 2022: 73 · 2021: 76 · 2020: 85 · 2019: 61 · 2018: 53 · 2017: 20 · 2016: 1
FWCI
40.25
Type
journal article
Language
en
Open access
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Advanced Functional Materials (publishedVersion)
  • Bilkent University Institutional Repository (Bilkent University) (submittedVersion)
Funders
National Research Foundation of Korea (2012R1A3A2048814)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Photodynamic Therapy Research Studies
  • Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
  • Physical Sciences › Materials Science › Materials Chemistry › Luminescence and Fluorescent Materials
Keywords
activatable photosensitizers, photodynamic therapy, singlet oxygen generation, theranostic agents, selective cytotoxicity, photosensitizer design

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