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Cited by 253

The DOI matches its Crossref record; 147 of the 147 references it cites were found in a registry or an index.

Advanced Biomaterials for Regulating Polarization of Macrophages in Wound Healing

Mao, Jiayi, Chen, Lu, Cai, Zhengwei, Qian, Shutong, Liu, Zhimo, Zhao, Binfan, Zhang, Yuguang, Sun, Xiaoming, Cui, Wenguo·2022·Advanced Functional Materials

Abstract

Macrophage immunotherapy is an emerging treatment strategy that modulates the immune system to promote wound healing. The functionality and regeneration of tissue depend on spatially and temporally regulating the biophysical and biochemical microenvironmental with poorly understood mechanisms. Biomaterials are carefully crafted to display and deliver macrophage regulatory signals in a precise and near‐physiological way, serving as powerful artificial microenvironments in which to explore and direct the fate of macrophages. The review starts with discussing the classification and function of macrophages, and then introduces the polarization of macrophages in different microenvironments of conventional wounds and chronic wounds. Recent advances in biomaterials that balance the phenotypes of macrophages in wound healing are emphasized. Finally, looking ahead, the potential ability of biomaterial scaffolds to modulate immune signaling to produce an environment conducive to regeneration is discussed.

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Crossref · 10.1002/adfm.202111003

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Metadata

Authors
Mao, J., Chen, L., Cai, Z., Qian, S., Liu, Z., Zhao, B., Zhang, Y., Sun, X., & Cui, W.
Venue
Advanced Functional Materials
Publisher
Wiley
Published
2021-12-05
Volume
32
Issue
12
ISSN
  • 1616-301X (ISSN-L)
  • 1616-3028
OpenAlex
W4200450281
Cited by
253
References
147
FWCI
13.44
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Advanced Biomaterials for Regulating Polarization of Macrophages in Wound Healing. https://app.cochat.ai/papers/10.1002/adfm.202111003
The paper
Mao, J., Chen, L., Cai, Z., Qian, S., Liu, Z., Zhao, B., Zhang, Y., Sun, X., & Cui, W. (2022). Advanced Biomaterials for Regulating Polarization of Macrophages in Wound Healing. Advanced Functional Materials. https://doi.org/10.1002/adfm.202111003

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.