The DOI matches its Crossref record; 147 of the 147 references it cites were found in a registry or an index.
Advanced Biomaterials for Regulating Polarization of Macrophages in Wound Healing
Abstract
Macrophage immunotherapy is an emerging treatment strategy that modulates the immune system to promote wound healing. The functionality and regeneration of tissue depend on spatially and temporally regulating the biophysical and biochemical microenvironmental with poorly understood mechanisms. Biomaterials are carefully crafted to display and deliver macrophage regulatory signals in a precise and near‐physiological way, serving as powerful artificial microenvironments in which to explore and direct the fate of macrophages. The review starts with discussing the classification and function of macrophages, and then introduces the polarization of macrophages in different microenvironments of conventional wounds and chronic wounds. Recent advances in biomaterials that balance the phenotypes of macrophages in wound healing are emphasized. Finally, looking ahead, the potential ability of biomaterial scaffolds to modulate immune signaling to produce an environment conducive to regeneration is discussed.
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Citations
Cites
1 retracted
Cellular responses to thermoresponsive stiffness memory elastomer nanohybrid scaffolds by 3D-TIPS
Wu, L., Magaz, A., Maughan, E. F., Oliver, N., Darbyshire, A., Loizidou, M., Emberton, M., Birchall, M., & Song, W. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.12.019 · Cited by 29
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Immunology of Acute and Chronic Wound Healing
Raziyeva, K., Kim, Y., Zharkinbekov, Z., Kassymbek, K., Jimi, S., & Saparov, A. (2021) · Biomolecules · doi:10.3390/biom11050700 · Cited by 1,049
Mesenchymal stem cell-macrophage crosstalk and bone healing
Pajarinen, J., Lin, T., Gibon, E., Kohno, Y., Maruyama, M., Nathan, K., Lu, L., Yao, Z., & Goodman, S. B. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2017.12.025 · Cited by 999
ROS-scavenging hydrogel to promote healing of bacteria infected diabetic wounds
Zhao, H., Huang, J., Li, Y., Lv, X., Zhou, H., Wang, H., Xu, Y., Wang, C., Wang, J., & Liu, Z. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120286 · Cited by 841
Self-citationTitanium surface characteristics, including topography and wettability, alter macrophage activation
Hotchkiss, K. M., Reddy, G. B., Hyzy, S. L., Schwartz, Z., Boyan, B. D., & Olivares-Navarrete, R. (2016) · Acta Biomaterialia · doi:10.1016/j.actbio.2015.12.003 · Cited by 680
Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing
Atcha, H., Jairaman, A., Holt, J. R., Meli, V. S., Nagalla, R. R., Veerasubramanian, P. K., Brumm, K. T., Lim, H. E., Othy, S., Cahalan, M. D., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-23482-5 · Cited by 644
Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells
Sadtler, K., Estrellas, K., Allen, B. W., Wolf, M. T., Fan, H., Tam, A. J., Patel, C. H., Luber, B. S., Wang, H., Wagner, K. R., et al. (2016) · Science · doi:10.1126/science.aad9272 · Cited by 605
Regulation of Macrophage Polarization and Wound Healing
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Cited by
Fu, M., Zhao, Y., Wang, Y., Li, Y., Wu, M., Liu, Q., Hou, Z., Lu, Z., Wu, K., & Guo, J. (2023) · Small · doi:10.1002/smll.202205489 · Cited by 107
Ben Amara, H., Martinez, D. C., Shah, F. A., Loo, A. J., Emanuelsson, L., Norlindh, B., Willumeit-Römer, R., Plocinski, T., Swieszkowski, W., Palmquist, A., et al. (2023) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.02.014 · Cited by 42
Metadata
- Authors
- Mao, J., Chen, L., Cai, Z., Qian, S., Liu, Z., Zhao, B., Zhang, Y., Sun, X., & Cui, W.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2021-12-05
- Volume
- 32
- Issue
- 12
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W4200450281
- Cited by
- 253
- References
- 147
- FWCI
- 13.44
- Type
- journal article
- Language
- en
- Open access
- closed
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- Mao, J., Chen, L., Cai, Z., Qian, S., Liu, Z., Zhao, B., Zhang, Y., Sun, X., & Cui, W. (2022). Advanced Biomaterials for Regulating Polarization of Macrophages in Wound Healing. Advanced Functional Materials. https://doi.org/10.1002/adfm.202111003
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.