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A Bioprinted Cardiac Patch Composed of Cardiac‐Specific Extracellular Matrix and Progenitor Cells for Heart Repair
Open accessAbstract
Congenital heart defects are present in 8 of 1000 newborns and palliative surgical therapy has increased survival. Despite improved outcomes, many children develop reduced cardiac function and heart failure requiring transplantation. Human cardiac progenitor cell (hCPC) therapy has potential to repair the pediatric myocardium through release of reparative factors, but therapy suffers from limited hCPC retention and functionality. Decellularized cardiac extracellular matrix hydrogel (cECM) improves heart function in animals, and human trials are ongoing. In the present study, a 3D‐bioprinted patch containing cECM for delivery of pediatric hCPCs is developed. Cardiac patches are printed with bioinks composed of cECM, hCPCs, and gelatin methacrylate (GelMA). GelMA‐cECM bioinks print uniformly with a homogeneous distribution of cECM and hCPCs. hCPCs maintain >75% viability and incorporation of cECM within patches results in a 30‐fold increase in cardiogenic gene expression of hCPCs compared to hCPCs grown in pure GelMA patches. Conditioned media from GelMA‐cECM patches show increased angiogenic potential (>2‐fold) over GelMA alone, as seen by improved endothelial cell tube formation. Finally, patches are retained on rat hearts and show vascularization over 14 d in vivo. This work shows the successful bioprinting and implementation of cECM‐hCPC patches for potential use in repairing damaged myocardium.
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“The concept is gaining traction, as the ability to print tissues composed entirely of native proteins, cells and/or biocompatible synthetic components is possible and accessible to many laboratories9–17.”
From In situ expansion, differentiation, and electromechanical coupling of human cardiac muscle in a 3D bioprinted, chambered organoid (2020) · cites this paper as [10]
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“Models that replicate the geometrically complex structure of the heart, harboring chambers and large vessels with soft biomaterials, can be achieved using 3D bioprinting.”
From In situ expansion, differentiation, and electromechanical coupling of human cardiac muscle in a 3D bioprinted, chambered organoid (2020) · cites this paper as [10]
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Bolli, R., Chugh, A. R., D’Amario, D., Loughran, J. H., Stoddard, M. F., Ikram, S., Beache, G. M., Wagner, S. G., Leri, A., Hosoda, T., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(11)61590-0 · Cited by 1,287
RetractedLutolf, M. P., & Hubbell, J. A. (2005) · Nature Biotechnology · doi:10.1038/nbt1055 · Cited by 4,551
Cell-laden microengineered gelatin methacrylate hydrogels
Nichol, J. W., Koshy, S. T., Bae, H., Hwang, C. M., Yamanlar, S., & Khademhosseini, A. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.03.064 · Cited by 2,377
Paracrine Mechanisms in Adult Stem Cell Signaling and Therapy
Gnecchi, M., Zhang, Z., Ni, A., & Dzau, V. J. (2008) · Circulation Research · doi:10.1161/circresaha.108.176826 · Cited by 2,069
Printing three-dimensional tissue analogues with decellularized extracellular matrix bioink
Pati, F., Jang, J., Ha, D.-H., Won Kim, S., Rhie, J.-W., Shim, J.-H., Kim, D.-H., & Cho, D.-W. (2014) · Nature Communications · doi:10.1038/ncomms4935 · Cited by 1,904
Extracellular-matrix tethering regulates stem-cell fate
Trappmann, B., Gautrot, J. E., Connelly, J. T., Strange, D. G. T., Li, Y., Oyen, M. L., Stuart, M. A. C., Boehm, H., Li, B., Viola Vogel, B., et al. (2012) · Nature Materials · doi:10.1038/nmat3339 · Cited by 1,570
Injectable hydrogels as unique biomedical materials
Yu, L., & Ding, J. (2008) · Chemical Society Reviews · doi:10.1039/b713009k · Cited by 1,545
Makkar, R., Smith, R. R., Cheng, K., Malliaras, K. G., Thomson, L., Berman, D. S., Czer, L. S. C., Marbán, L., Mendizabal, A. M., Johnston, P. V., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60195-0 · Cited by 1,423
Stem-cell therapy for cardiac disease
Segers, V. F. M., & Lee, R. T. (2008) · Nature · doi:10.1038/nature06800 · Cited by 1,192
Bioink properties before, during and after 3D bioprinting
Hölzl, K., Lin, S., Tytgat, L., Vlierberghe, S. V., Gu, L., & Ovsianikov, A. (2016) · Biofabrication · doi:10.1088/1758-5090/8/3/032002 · Cited by 1,129
Research works printed but not linked: 5
- Rossano J. W., 2010, Circulation, 122, A1374
- Robbins J. M., 2007, MMWR, 56, 25
- French K. M., 2016, Stem Cell Transl. Med.
- Stastna M., 2012, Circ. Genom. Precis. Med., 5, 8
- DeCicco‐Skinner K. L., 2014, J. Visualized Exp., e51312
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Lim, K. S., Galarraga, J. H., Cui, X., Lindberg, G. C. J., Burdick, J. A., & Woodfield, T. B. F. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00812 · Cited by 449
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Kupfer, M. E., Lin, W.-H., Ravikumar, V., Qiu, K., Wang, L., Gao, L., Bhuiyan, D. B., Lenz, M., Ai, J., Mahutga, R. R., et al. (2020) · Circulation Research · doi:10.1161/circresaha.119.316155 · Cited by 329
Porzionato, A., Stocco, E., Barbon, S., Grandi, F., Macchi, V., & De Caro, R. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19124117 · Cited by 319
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Zhang, F., & King, M. W. (2020) · Advanced Healthcare Materials · doi:10.1002/adhm.201901358 · Cited by 320
Traverse, J. H., Henry, T. D., Dib, N., Patel, A. N., Pepine, C. J., Schaer, G. L., DeQuach, J. A., Kinsey, A. M., Chamberlin, P., & Christman, K. L. (2019) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2019.07.012 · Cited by 309
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Brown, M., Li, J., Moraes, C., Tabrizian, M., & Li-Jessen, N. Y. K. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121786 · Cited by 282
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Golebiowska, A. A., Intravaia, J. T., Sathe, V. M., Kumbar, S. G., & Nukavarapu, S. P. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.09.017 · Cited by 236
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Self-citationHuang, K., Ozpinar, E. W., Su, T., Tang, J., Shen, D., Qiao, L., Hu, S., Li, Z., Liang, H., Mathews, K. G., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aat9683 · Cited by 216
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Basara, G., Saeidi‐Javash, M., Ren, X., Bahçecioğlu, G., Wyatt, B. C., Anasori, B., Zhang, Y., & Zorlutuna, P. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.12.033 · Cited by 171
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Liu, N., Ye, X., Yao, B., Zhao, M., Wu, P., Liu, G., Zhuang, D., Jiang, H., Chen, X., He, Y., et al. (2020) · Bioactive Materials · doi:10.1016/j.bioactmat.2020.10.021 · Cited by 156
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Han, W., Singh, N. K., Kim, J. J., Kim, H., Kim, B. S., Park, J. Y., Jang, J., & Cho, D. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119496 · Cited by 132
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Liao, J., Xu, B., Zhang, R., Fan, Y., Xie, H., & Li, X. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb01534b · Cited by 133
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Ghosh, R. N., Thomas, J., Vaidehi, B. R., G., D. N., Janardanan, A., Namboothiri, P. K., & Peter, M. (2023) · Materials Advances · doi:10.1039/d3ma00715d · Cited by 125
Ng, W. L., An, J., & Chua, C. K. (2024) · Engineering · doi:10.1016/j.eng.2024.01.028 · Cited by 122
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Yang, Z., Xu, H., & Zhao, X. (2020) · Advanced Science · doi:10.1002/advs.201903718 · Cited by 124
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Yang, X., Ma, Y., Wang, X., Yuan, S., Huo, F., Yi, G., Zhang, J., Yang, B., & Tian, W. (2022) · Advanced Science · doi:10.1002/advs.202205041 · Cited by 92
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Wu, C. A., Zhu, Y., & Woo, Y.-P. J. (2023) · Bioengineering · doi:10.3390/bioengineering10070842 · Cited by 87
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Agarwal, T., Fortunato, G. M., Hann, S.-Y., Ayan, B., Vajanthri, K. Y., Presutti, D., Cui, H., Chan, A., Costantini, M., Onesto, V., et al. (2021) · Materials Science and Engineering C · doi:10.1016/j.msec.2021.112057 · Cited by 68
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Theus, A. S., Tomov, M. L., Cetnar, A. C., Lima, B., Nish, J., McCoy, K., Mahmoudi, M., & Serpooshan, V. (2019) · Emergent Materials · doi:10.1007/s42247-019-00039-3 · Cited by 58
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He, L., & Chen, D. (2020) · Advanced Healthcare Materials · doi:10.1002/adhm.202001175 · Cited by 52
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Lee, J. S., Choi, Y. S., Lee, J. S., Jeon, E. J., An, S., Lee, M. S., Yang, H. S., & Cho, S. (2021) · Chemical Engineering Journal · doi:10.1016/j.cej.2021.130926 · Cited by 48
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Tan, X., Zhang, J., Heng, Y., Chen, L., Wang, Y., Wu, S., Liu, X., Xu, B., Yu, Z., & Gu, R. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.02.035 · Cited by 47
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Liu, H., Gong, Y., Zhang, K., Ke, S., Wang, Y., Wang, J., & Wang, H. (2023) · Gels · doi:10.3390/gels9030195 · Cited by 50
Gregory, D. A., Fricker, A. T. R., Mitrev, P., Ray, M., Asare, E., Sim, D., Larpnimitchai, S., Zhang, Z., Ma, J., Tetali, S. S. V., et al. (2023) · Journal of Functional Biomaterials · doi:10.3390/jfb14010040 · Cited by 46
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Metadata
- Authors
- Bejleri, D., Streeter, B. W., Nachlas, A. L. Y., Brown, M. E., Gaetani, R., Christman, K. L., & Davis, M. E.
- Affiliations
- Georgia Institute of Technology (US)
- University of California San Diego (US)
- Corresponding author
- Davis, Michael E.
- Venue
- Advanced Healthcare Materials
- Publisher
- Wiley
- Published
- 2018-10-31
- Volume
- 7
- Issue
- 23
- Pages
- e1800672-e1800672
- ISSN
- 2192-2640 (ISSN-L)
- 2192-2659
- PMC
- PMC6521871
- OpenAlex
- W2899402424
- Cited by
- 255
- References
- 60
- Citations by year
- 2026: 14 · 2025: 28 · 2024: 29 · 2023: 46 · 2022: 36 · 2021: 41 · 2020: 41 · 2019: 17 · 2018: 3
- FWCI
- 26.50
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Advanced Healthcare Materials (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- IRIS Research product catalog (Sapienza University of Rome) (submittedVersion, other-oa)
- Funders
- National Heart, Lung, and Blood Institute (R01HL113468)
- Topics
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
- Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
- Keywords
- 3D bioprinting, cardiac patch, congenital heart disease, pediatric heart failure, gelatin methacryloyl, bioinks, cardiomyocyte differentiation, angiogenesis, endothelial tube formation, vascularization, myocardial repair, cell retention
- MeSH terms
- Animals, Cells, Cultured, Extracellular Matrix, Gelatin, Heart Diseases, Humans, Myocardium, Stem Cells, Rats, Sprague-Dawley, Hydrogels, Tissue Engineering, Myocytes, Cardiac, Stem Cell Transplantation, Rats, Tissue Scaffolds, Elastic Modulus, Bioprinting, Printing, Three-Dimensional
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